Pathogenic Roles of Glutamic Acid Decarboxylase 65 Autoantibodies in Cerebellar Ataxias

The physiological basis of therapies for cerebellar ataxias

(2016) Hiroshi Mitoma et al.   Therapeutic Advances in Neurological Disorders

Consensus Paper: Neuroimmune Mechanisms of Cerebellar Ataxias

(2015) Hiroshi Mitoma et al.   CEREBELLUM

Main path and byways: non-vesicular glutamate release by system xc−as an important modifier of glutamatergic neurotransmission

(2015) Ann Massie et al.   JOURNAL OF NEUROCHEMISTRY

GAD65 epitope mapping and search for novel autoantibodies in GAD-associated neurological disorders

(2015) P. Fouka et al.   JOURNAL OF NEUROIMMUNOLOGY

Experiencia en el tratamiento con inmunoterapia en 3 pacientes con ataxia cerebelosa asociada a anticuerpos anticarboxilasa del ácido glutámico

(2015) I. Rouco et al.   NEUROLOGIA

Implications of glial nitric oxide in neurodegenerative diseases

(2015) Jose Enrique Yuste et al.   Frontiers in Cellular Neuroscience

Disease-specific monoclonal antibodies targeting glutamate decarboxylase impair GABAergic neurotransmission and affect motor learning and behavioral functions

(2015) Mario Manto et al.   Frontiers in Behavioral Neuroscience

Paraneoplastic Neurological Syndromes and Glutamic Acid Decarboxylase Antibodies

(2015) Helena Ariño et al.   JAMA Neurology

The Role of Excitotoxic Programmed Necrosis in Acute Brain Injury

(2015) Denson G. Fujikawa   Computational and Structural Biotechnology Journal

Antibodies to Inhibitory Synaptic Proteins in Neurological Syndromes Associated with Glutamic Acid Decarboxylase Autoimmunity

(2015) Nuria Gresa-Arribas et al.   PLoS One

Progressive cerebellar ataxia and new-onset diabetes

(2014) Marie-France Kong et al.   LANCET

Tumor Necrosis Factor Alpha: A Link between Neuroinflammation and Excitotoxicity

(2014) Gabriel Olmos et al.   MEDIATORS OF INFLAMMATION

Releasing Dentate Nucleus Cells from Purkinje Cell Inhibition Generates Output from the Cerebrocerebellum

(2014) Takahiro Ishikawa et al.   PLoS One

Cerebellar Ataxia and Glutamic Acid Decarboxylase Antibodies

(2014) Helena Ariño et al.   JAMA Neurology

Intravenous Immunoglobulin and Rituximab for Cerebellar Ataxia with Glutamic Acid Decarboxylase Autoantibodies

(2013) Vincent Planche et al.   CEREBELLUM

The GABAergic Septohippocampal Pathway Is Directly Involved in Internal Processes Related to Operant Reward Learning

(2013) G. Vega-Flores et al.   CEREBRAL CORTEX

Neuron-Microglia Interaction in Neuroinflammation

(2013) Akio Suzumura   CURRENT PROTEIN & PEPTIDE SCIENCE

Interleukin-1  Alters Glutamate Transmission at Purkinje Cell Synapses in a Mouse Model of Multiple Sclerosis

(2013) G. Mandolesi et al.   JOURNAL OF NEUROSCIENCE

Monoclonal antibodies to 65kDa glutamate decarboxylase induce epitope specific effects on motor and cognitive functions in rats

(2013) Christiane S Hampe et al.   Orphanet Journal of Rare Diseases

Neuronal autoantigens—pathogenesis, associated disorders and antibody testing

(2012) Eric Lancaster et al.   Nature Reviews Neurology

Consensus Paper: Roles of the Cerebellum in Motor Control—The Diversity of Ideas on Cerebellar Involvement in Movement

(2011) Mario Manto et al.   CEREBELLUM

Regulation of microglia by ionotropic glutamatergic and GABAergic neurotransmission

(2011) Wai T. Wong et al.   Neuron Glia Biology

In vivo effects of antibodies from patients with anti-NMDA receptor encephalitis: further evidence of synaptic glutamatergic dysfunction

(2011) Mario Manto et al.   Orphanet Journal of Rare Diseases

Respective implications of glutamate decarboxylase antibodies in stiff person syndrome and cerebellar ataxia

(2011) Mario U Manto et al.   Orphanet Journal of Rare Diseases

Stiff person syndrome-associated autoantibodies to amphiphysin mediate reduced GABAergic inhibition

(2010) Christian Geis et al.   BRAIN

Clinico-pathological findings in a patient with progressive cerebellar ataxia, autoimmune polyendocrine syndrome, hepatocellular carcinoma and anti-GAD autoantibodies

(2010) Giovanni Piccolo et al.   JOURNAL OF THE NEUROLOGICAL SCIENCES

Refractory generalized seizures and cerebellar ataxia associated with anti-GAD antibodies responsive to immunosuppressive treatment

(2009) V. Nociti et al.   EUROPEAN JOURNAL OF NEUROLOGY

Cerebellar Purkinje cells incorporate immunoglobulins and immunotoxins in vitro: implications for human neurological disease and immunotherapeutics

(2009) Kenneth E Hill et al.   Journal of Neuroinflammation

Increased spontaneous activity of a network of hippocampal neurons in culture caused by suppression of inhibitory potentials mediated by anti-gad antibodies

(2008) Marika Vianello et al.   AUTOIMMUNITY

COOH-Terminal Clustering of Autoantibody and T-Cell Determinants on the Structure of GAD65 Provide Insights Into the Molecular Basis of Autoreactivity

(2008) G. Fenalti et al.   DIABETES

Auto-immune cerebellar ataxia with anti-GAD antibodies accompanied by de novo late-onset type 1 diabetes mellitus

(2008) C. Bayreuther et al.   DIABETES & METABOLISM

Reversibility of cerebellar GABAergic synapse impairment induced by anti-glutamic acid decarboxylase autoantibodies

(2008) Kazuyuki Ishida et al.   JOURNAL OF THE NEUROLOGICAL SCIENCES

Cerebellar ataxia as a possible organ-specific autoimmune disease

(2008) Marios Hadjivassiliou et al.   MOVEMENT DISORDERS