The Differential Contribution of the Innate Immune System to a Good Pathological Response in the Breast and Axillary Lymph Nodes Induced by Neoadjuvant Chemotherapy in Women with Large and Locally Advanced Breast Cancers

Perils of the Pathologic Complete Response

(2016) Brent S. Rose et al.   JOURNAL OF CLINICAL ONCOLOGY

Crucial Contributions by T Lymphocytes (Effector, Regulatory, and Checkpoint Inhibitor) and Cytokines (TH1, TH2, and TH17) to a Pathological Complete Response Induced by Neoadjuvant Chemotherapy in Women with Breast Cancer

(2016) Viriya Kaewkangsadan et al.   Journal of Immunology Research

Classifying Cancers Based on T-cell Infiltration and PD-L1

(2015) Michele W.L. Teng et al.   CANCER RESEARCH

Natural killer (NK) cell profiles in blood and tumour in women with large and locally advanced breast cancer (LLABC) and their contribution to a pathological complete response (PCR) in the tumour following neoadjuvant chemotherapy (NAC): differential restoration of blood profiles by NAC and surgery

(2015) Chandan Verma et al.   Journal of Translational Medicine

Women with large (≥3 cm) and locally advanced breast cancers (T3, 4, N1, 2, M0) receiving neoadjuvant chemotherapy (NAC: cyclophosphamide, doxorubicin, docetaxel): addition of capecitabine improves 4-year disease-free survival

(2015) Jennifer Eremin et al.   SpringerPlus

CD8+ Tumor-Infiltrating T Cells Are Trapped in the Tumor-Dendritic Cell Network

(2015) Alexandre Boissonnas et al.   NEOPLASIA

Prognostic value of tumor-infiltrating lymphocytes on residual disease after primary chemotherapy for triple-negative breast cancer: a retrospective multicenter study

(2014) M. V. Dieci et al.   ANNALS OF ONCOLOGY

SnapShot: Cancer Vaccines

(2014) Karolina Palucka et al.   CELL

Tumor-Associated Macrophages: From Mechanisms to Therapy

(2014) Roy Noy et al.   IMMUNITY

Pathological complete response and long-term clinical benefit in breast cancer: the CTNeoBC pooled analysis

(2014) Patricia Cortazar et al.   LANCET

Breast cancer subtyping by immunohistochemistry and histological grade outperforms breast cancer intrinsic subtypes in predicting neoadjuvant chemotherapy response

(2013) E. H. Lips et al.   BREAST CANCER RESEARCH AND TREATMENT

Tumour-infiltrating CD8+ lymphocytes as an independent predictive factor for pathological complete response to primary systemic therapy in breast cancer

(2013) A N Seo et al.   BRITISH JOURNAL OF CANCER

Predictive and prognostic factors in locally advanced breast cancer: effect of intratumoral FOXP3+ Tregs

(2013) Lutfiye Demir et al.   CLINICAL & EXPERIMENTAL METASTASIS

From the immune contexture to the Immunoscore: the role of prognostic and predictive immune markers in cancer

(2013) Helen Angell et al.   CURRENT OPINION IN IMMUNOLOGY

The Continuum of Cancer Immunosurveillance: Prognostic, Predictive, and Mechanistic Signatures

(2013) Jérôme Galon et al.   IMMUNITY

Abnormal T regulatory cells (Tregs: FOXP3+, CTLA-4+), myeloid-derived suppressor cells (MDSCs: monocytic, granulocytic) and polarised T helper cell profiles (Th1, Th2, Th17) in women with large and locally advanced breast cancers undergoing neoadjuvant chemotherapy (NAC) and surgery: failure of abolition of abnormal treg profile with treatment and correlation of treg levels with pathological response to NAC

(2013) Chandan Verma et al.   Journal of Translational Medicine

Pathological Mobilization and Activities of Dendritic Cells in Tumor-Bearing Hosts: Challenges and Opportunities for Immunotherapy of Cancer

(2013) Amelia J. Tesone et al.   Frontiers in Immunology

Human Plasmacytoid Dendritic Cells: From Molecules to Intercellular Communication Network

(2013) Till S. M. Manuel Mathan et al.   Frontiers in Immunology

Immunogenic Cell Death in Cancer Therapy

(2012) Guido Kroemer et al.   Annual Review of Immunology

Characterisation of tumour-infiltrating macrophages: impact on response and survival in patients receiving primary chemotherapy for breast cancer

(2012) Steven D. Heys et al.   BREAST CANCER RESEARCH AND TREATMENT

Peritumoral FOXP3+ regulatory T cell is sensitive to chemotherapy while intratumoral FOXP3+ regulatory T cell is prognostic predictor of breast cancer patients

(2012) Fangfang Liu et al.   BREAST CANCER RESEARCH AND TREATMENT

Intratumoral regulatory T cells as an independent predictive factor for pathological complete response to neoadjuvant paclitaxel followed by 5-FU/epirubicin/cyclophosphamide in breast cancer patients

(2012) Naofumi Oda et al.   BREAST CANCER RESEARCH AND TREATMENT

Neutrophils and granulocytic myeloid-derived suppressor cells: immunophenotyping, cell biology and clinical relevance in human oncology

(2012) Claudia A. Dumitru et al.   CANCER IMMUNOLOGY IMMUNOTHERAPY

A novel pathway combining calreticulin exposure and ATP secretion in immunogenic cancer cell death

(2012) Abhishek D Garg et al.   EMBO JOURNAL

Tumor-infiltrating lymphocytes are important pathologic predictors for neoadjuvant chemotherapy in patients with breast cancer

(2012) Rin Yamaguchi et al.   HUMAN PATHOLOGY

The multi-faceted roles of prostaglandin E2 in cancer-infiltrating mononuclear phagocyte biology

(2012) Weixiao Sha et al.   IMMUNOBIOLOGY

Definition and Impact of Pathologic Complete Response on Prognosis After Neoadjuvant Chemotherapy in Various Intrinsic Breast Cancer Subtypes

(2012) Gunter von Minckwitz et al.   JOURNAL OF CLINICAL ONCOLOGY

Pathologic Complete Response Predicts Recurrence-Free Survival More Effectively by Cancer Subset: Results From the I-SPY 1 TRIAL—CALGB 150007/150012, ACRIN 6657

(2012) Laura J. Esserman et al.   JOURNAL OF CLINICAL ONCOLOGY

The Distribution of Macrophages with a M1 or M2 Phenotype in Relation to Prognosis and the Molecular Characteristics of Colorectal Cancer

(2012) Sofia Edin et al.   PLoS One

Cardiac Glycosides Exert Anticancer Effects by Inducing Immunogenic Cell Death

(2012) L. Menger et al.   Science Translational Medicine

The presence of sinusoidal CD163+ macrophages in lymph nodes is associated with favorable nodal status in patients with breast cancer

(2012) Aaron S. Mansfield et al.   VIRCHOWS ARCHIV

Effects on quality of life, anti-cancer responses, breast conserving surgery and survival with neoadjuvant docetaxel: a randomised study of sequential weekly versus three-weekly docetaxel following neoadjuvant doxorubicin and cyclophosphamide in women with primary breast cancer

(2011) Leslie G Walker et al.   BMC CANCER

Tumor-infiltrating lymphocytes are correlated with response to neoadjuvant chemotherapy in triple-negative breast cancer

(2011) Makiko Ono et al.   BREAST CANCER RESEARCH AND TREATMENT

Predictive clinical outcome of the intratumoral CD66b-positive neutrophil-to-CD8-positive T-cell ratio in patients with resectable nonsmall cell lung cancer

(2011) Marius Ilie et al.   CANCER

Pivotal Role of Innate and Adaptive Immunity in Anthracycline Chemotherapy of Established Tumors

(2011) S. R. Mattarollo et al.   CANCER RESEARCH

Prognostic and Predictive Impact of Intra- and Peritumoral Immune Infiltrates

(2011) W. H. Fridman et al.   CANCER RESEARCH

SnapShot: Dendritic Cells

(2011) Juliana Idoyaga et al.   CELL

In situ immune response after neoadjuvant chemotherapy for breast cancer predicts survival

(2011) Sylvain Ladoire et al.   JOURNAL OF PATHOLOGY

Metastasis to sentinel lymph nodes in breast cancer is associated with maturation arrest of dendritic cells and poor co-localization of dendritic cells and CD8+ T cells

(2011) Aaron Scott Mansfield et al.   VIRCHOWS ARCHIV

Immune Modulation by Chemotherapy or Immunotherapy to Enhance Cancer Vaccines

(2011) Genevieve M. Weir et al.   Cancers

5-Fluorouracil Selectively Kills Tumor-Associated Myeloid-Derived Suppressor Cells Resulting in Enhanced T Cell-Dependent Antitumor Immunity

(2010) J. Vincent et al.   CANCER RESEARCH

Macrophage Diversity Enhances Tumor Progression and Metastasis

(2010) Bin-Zhi Qian et al.   CELL

The paradox of tumor-associated neutrophils: Fueling tumor growth with cytotoxic substances

(2010) A. McGarry Houghton   CELL CYCLE

Consecutive low doses of cyclophosphamide preferentially target Tregs and potentiate T cell responses induced by DNA PLG microparticle immunization

(2010) Christine M. Barbon et al.   CELLULAR IMMUNOLOGY

Neutrophils responsive to endogenous IFN-β regulate tumor angiogenesis and growth in a mouse tumor model

(2010) Jadwiga Jablonska et al.   JOURNAL OF CLINICAL INVESTIGATION

Intratumoral neutrophils: A poor prognostic factor for hepatocellular carcinoma following resection

(2010) Yi-Wei Li et al.   JOURNAL OF HEPATOLOGY

The density of macrophages in the invasive front is inversely correlated to liver metastasis in colon cancer

(2010) Qiang Zhou et al.   Journal of Translational Medicine

Doxorubicin enhances CD4+ T-cell immune responses by inducing expression of CD40 ligand and 4-1BB

(2009) Jae Yeo Park et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Presence of Intratumoral Neutrophils Is an Independent Prognostic Factor in Localized Renal Cell Carcinoma

(2009) Hanne Krogh Jensen et al.   JOURNAL OF CLINICAL ONCOLOGY

Tumor-Associated Lymphocytes As an Independent Predictor of Response to Neoadjuvant Chemotherapy in Breast Cancer

(2009) Carsten Denkert et al.   JOURNAL OF CLINICAL ONCOLOGY

Human Dendritic Cells Produce TGF- 1 under the Influence of Lung Carcinoma Cells and Prime the Differentiation of CD4+CD25+Foxp3+ Regulatory T Cells

(2009) I. E. Dumitriu et al.   JOURNAL OF IMMUNOLOGY

Macrophages define the invasive microenvironment in breast cancer

(2008) Jeffrey W. Pollard   JOURNAL OF LEUKOCYTE BIOLOGY

Cancer-related inflammation

(2008) Alberto Mantovani et al.   NATURE