Microbial Regulation of Glucose Metabolism and Insulin Resistance

Transfer of dysbiotic gut microbiota has beneficial effects on host liver metabolism

(2017) Simon Nicolas et al.   Molecular Systems Biology

Metformin alters the gut microbiome of individuals with treatment-naive type 2 diabetes, contributing to the therapeutic effects of the drug

(2017) Hao Wu et al.   NATURE MEDICINE

Lactobacillus casei CCFM419 attenuates type 2 diabetes via a gut microbiota dependent mechanism

(2017) Gang Wang et al.   Food & Function

Effects of Lactobacillus casei CCFM419 on insulin resistance and gut microbiota in type 2 diabetic mice

(2017) X. Li et al.   Beneficial Microbes

Effect of multi-strain probiotics (multi-strain microbial cell preparation) on glycemic control and other diabetes-related outcomes in people with type 2 diabetes: a randomized controlled trial

(2016) Somayyeh Firouzi et al.   EUROPEAN JOURNAL OF NUTRITION

Diet-induced extinctions in the gut microbiota compound over generations

(2016) Erica D. Sonnenburg et al.   NATURE

Looking for a Signal in the Noise: Revisiting Obesity and the Microbiome

(2016) Marc A. Sze et al.   mBio

Microbially produced glucagon-like peptide 1 improves glucose tolerance in mice

(2016) Tulika Arora et al.   Molecular Metabolism

Promoting Health and Longevity through Diet: From Model Organisms to Humans

(2015) Luigi Fontana et al.   CELL

Personalized Nutrition by Prediction of Glycemic Responses

(2015) David Zeevi et al.   CELL

Interactions between Gut Microbiota, Host Genetics and Diet Modulate the Predisposition to Obesity and Metabolic Syndrome

(2015) Siegfried Ussar et al.   Cell Metabolism

Dietary Fiber-Induced Improvement in Glucose Metabolism Is Associated with Increased Abundance of Prevotella

(2015) Petia Kovatcheva-Datchary et al.   Cell Metabolism

Intake ofLactobacillus reuteriImproves Incretin and Insulin Secretion in Glucose-Tolerant Humans: A Proof of Concept

(2015) Marie-Christine Simon et al.   DIABETES CARE

Lactobacillus rhamnosus GG improves glucose tolerance through alleviating ER stress and suppressing macrophage activation in db/db mice

(2015) Kun-Young Park et al.   JOURNAL OF CLINICAL BIOCHEMISTRY AND NUTRITION

Effects of Antibiotics on Human Microbiota and Subsequent Disease

(2014) Kristie M. Keeney et al.   Annual Review of Microbiology

Altering the Intestinal Microbiota during a Critical Developmental Window Has Lasting Metabolic Consequences

(2014) Laura M. Cox et al.   CELL

Microbial Modulation of Insulin Sensitivity

(2014) Muhammad Tanweer Khan et al.   Cell Metabolism

The effects of probiotic bacteria on glycaemic control in overweight men and women: a randomised controlled trial

(2014) K L Ivey et al.   EUROPEAN JOURNAL OF CLINICAL NUTRITION

Comparative metabolomics in vegans and omnivores reveal constraints on diet-dependent gut microbiota metabolite production

(2014) Gary D Wu et al.   GUT

Impact of diet and individual variation on intestinal microbiota composition and fermentation products in obese men

(2014) Anne Salonen et al.   ISME Journal

Gut Microbiota Signatures Predict Host and Microbiota Responses to Dietary Interventions in Obese Individuals

(2014) Katri Korpela et al.   PLoS One

Meta-Analysis of Genome-Wide Association Studies in African Americans Provides Insights into the Genetic Architecture of Type 2 Diabetes

(2014) Maggie C. Y. Ng et al.   PLoS Genetics

Effect of Multispecies Probiotic Supplements on Metabolic Profiles, hs-CRP, and Oxidative Stress in Patients with Type 2 Diabetes

(2013) Zatollah Asemi et al.   ANNALS OF NUTRITION AND METABOLISM

Moderate GLUT4 Overexpression Improves Insulin Sensitivity and Fasting Triglyceridemia in High-Fat Diet-Fed Transgenic Mice

(2013) B. J. Atkinson et al.   DIABETES

High-Fat Diet-Mediated Lipotoxicity and Insulin Resistance Is Related to Impaired Lipase Expression in Mouse Skeletal Muscle

(2013) Pierre-Marie Badin et al.   ENDOCRINOLOGY

Therapeutic Potential of Fecal Microbiota Transplantation

(2013) Loek P. Smits et al.   GASTROENTEROLOGY

A gut prediction

(2013) Willem M. de Vos et al.   NATURE

Richness of human gut microbiome correlates with metabolic markers

(2013) Emmanuelle Le Chatelier et al.   NATURE

Diet rapidly and reproducibly alters the human gut microbiome

(2013) Lawrence A. David et al.   NATURE

Gut metagenome in European women with normal, impaired and diabetic glucose control

(2013) Fredrik H. Karlsson et al.   NATURE

Medicines from microbiota

(2013) Bernat Olle   NATURE BIOTECHNOLOGY

Intestinal microbiota metabolism of l-carnitine, a nutrient in red meat, promotes atherosclerosis

(2013) Robert A Koeth et al.   NATURE MEDICINE

The gut microbiota — masters of host development and physiology

(2013) Felix Sommer et al.   NATURE REVIEWS MICROBIOLOGY

Duodenal Infusion of Donor Feces for Recurrent Clostridium difficile

(2013) Els van Nood et al.   NEW ENGLAND JOURNAL OF MEDICINE

Gut Microbiota from Twins Discordant for Obesity Modulate Metabolism in Mice

(2013) V. K. Ridaura et al.   SCIENCE

Fiber and Prebiotics: Mechanisms and Health Benefits

(2013) Joanne Slavin   Nutrients

Dietary fibre consumption and insulin resistance – the role of body fat and physical activity

(2012) Charity B. Breneman et al.   BRITISH JOURNAL OF NUTRITION

Mechanisms for Insulin Resistance: Common Threads and Missing Links

(2012) Varman T. Samuel et al.   CELL

Intestinal MicrobiOMICS to Define Health and Disease in Human and Mice

(2012) Matteo Serino et al.   CURRENT PHARMACEUTICAL BIOTECHNOLOGY

The Role of Endogenous Incretin Secretion as Amplifier of Glucose-Stimulated Insulin Secretion in Healthy Subjects and Patients With Type 2 Diabetes

(2012) H. J. Woerle et al.   DIABETES

Lipid-Induced Insulin Resistance Is Not Mediated by Impaired Transcapillary Transport of Insulin and Glucose in Humans

(2012) J. Szendroedi et al.   DIABETES

Pancreatic diabetes manifests when beta cell area declines by approximately 65% in humans

(2012) J. J. Meier et al.   DIABETOLOGIA

Fatty liver as a consequence and cause of insulin resistance: Lessons from type 2 diabetic liver

(2012) Toshinari Takamura et al.   ENDOCRINE JOURNAL

Transfer of Intestinal Microbiota From Lean Donors Increases Insulin Sensitivity in Individuals With Metabolic Syndrome

(2012) Anne Vrieze et al.   GASTROENTEROLOGY

A metagenomic insight into our gut's microbiome

(2012) Patricia Lepage et al.   GUT

Intestinal microbiota determines development of non-alcoholic fatty liver disease in mice

(2012) Tiphaine Le Roy et al.   GUT

The role of dietary fatty acids in the pathology of metabolic syndrome

(2012) Ana Maria Lottenberg et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

A metagenome-wide association study of gut microbiota in type 2 diabetes

(2012) Junjie Qin et al.   NATURE

Functional interactions between the gut microbiota and host metabolism

(2012) Valentina Tremaroli et al.   NATURE

Inflammasome-mediated dysbiosis regulates progression of NAFLD and obesity

(2012) Jorge Henao-Mejia et al.   NATURE

Lymphotoxin regulates commensal responses to enable diet-induced obesity

(2012) Vaibhav Upadhyay et al.   NATURE IMMUNOLOGY

The gut microbiota—a clinical perspective on lessons learned

(2012) Fergus Shanahan   Nature Reviews Gastroenterology & Hepatology

Hydroxypropyl methylcellulose, a viscous soluble fiber, reduces insulin resistance and decreases fatty liver in Zucker Diabetic Fatty rats

(2012) David A Brockman et al.   Nutrition & Metabolism

Role of dietary beta-glucans in the prevention of the metabolic syndrome

(2012) Lieselotte Cloetens et al.   NUTRITION REVIEWS

Effects of psyllium on metabolic syndrome risk factors

(2012) Sebely Pal et al.   Obesity Reviews

Insulin in the brain: There and back again

(2012) William A. Banks et al.   PHARMACOLOGY & THERAPEUTICS

Prebiotic fibres dose-dependently increase satiety hormones and alter Bacteroidetes and Firmicutes in lean and obese JCR:LA-cp rats

(2011) Jill A. Parnell et al.   BRITISH JOURNAL OF NUTRITION

Liver Enzymes Are Associated With Hepatic Insulin Resistance, Insulin Secretion, and Glucagon Concentration in Healthy Men and Women

(2011) F. Bonnet et al.   DIABETES

The therapeutic potential of manipulating gut microbiota in obesity and type 2 diabetes mellitus

(2011) R. S. Kootte et al.   DIABETES OBESITY & METABOLISM

Foods for the prevention of diabetes: how do they work?

(2011) Theodoros Thomas et al.   DIABETES-METABOLISM RESEARCH AND REVIEWS

Deep congenic analysis identifies many strong, context-dependent QTLs, one of which, Slc35b4, regulates obesity and glucose homeostasis

(2011) S. N. Yazbek et al.   GENOME RESEARCH

Obesity-associated gut microbiota is enriched in Lactobacillus reuteri and depleted in Bifidobacterium animalis and Methanobrevibacter smithii

(2011) M Million et al.   INTERNATIONAL JOURNAL OF OBESITY

Gut microbiome, obesity, and metabolic dysfunction

(2011) Herbert Tilg et al.   JOURNAL OF CLINICAL INVESTIGATION

Effect of probiotic yogurt containing Lactobacillus acidophilus and Bifidobacterium lactis on lipid profile in individuals with type 2 diabetes mellitus

(2011) H.S. Ejtahed et al.   JOURNAL OF DAIRY SCIENCE

National, regional, and global trends in fasting plasma glucose and diabetes prevalence since 1980: systematic analysis of health examination surveys and epidemiological studies with 370 country-years and 2·7 million participants

(2011) Goodarz Danaei et al.   LANCET

The role of mitochondria in insulin resistance and type 2 diabetes mellitus

(2011) Julia Szendroedi et al.   Nature Reviews Endocrinology

Probiotic yogurt improves antioxidant status in type 2 diabetic patients

(2011) Hanie S. Ejtahed et al.   NUTRITION

The gut microbiome as therapeutic target

(2011) Patrice D. Cani et al.   PHARMACOLOGY & THERAPEUTICS

Systems genetics of susceptibility to obesity-induced diabetes in mice

(2011) Richard C. Davis et al.   PHYSIOLOGICAL GENOMICS

Skeletal Muscle Phosphodiester Content Relates to Body Mass and Glycemic Control

(2011) Julia Szendroedi et al.   PLoS One

Metagenomic systems biology of the human gut microbiome reveals topological shifts associated with obesity and inflammatory bowel disease

(2011) S. Greenblum et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Fats, inflammation and insulin resistance: insights to the role of macrophage and T-cell accumulation in adipose tissue

(2011) Karen A. Harford et al.   PROCEEDINGS OF THE NUTRITION SOCIETY

Linking Long-Term Dietary Patterns with Gut Microbial Enterotypes

(2011) G. D. Wu et al.   SCIENCE

Effects of Lactobacillus acidophilus NCFM on insulin sensitivity and the systemic inflammatory response in human subjects

(2010) Anne Sofie Andreasen et al.   BRITISH JOURNAL OF NUTRITION

Genetics of type 2 diabetes: pathophysiologic and clinical relevance

(2010) Christian Herder et al.   EUROPEAN JOURNAL OF CLINICAL INVESTIGATION

Beneficial effect of oral administration of Lactobacillus casei strain Shirota on insulin resistance in diet-induced obesity mice

(2010) E. Naito et al.   JOURNAL OF APPLIED MICROBIOLOGY

Pathogenesis of Insulin Resistance in Skeletal Muscle

(2010) Muhammad A. Abdul-Ghani et al.   JOURNAL OF BIOMEDICINE AND BIOTECHNOLOGY

Lipid-induced insulin resistance: unravelling the mechanism

(2010) Varman T Samuel et al.   LANCET

A human gut microbial gene catalogue established by metagenomic sequencing

(2010) Junjie Qin et al.   NATURE

Gut Microbiota in Human Adults with Type 2 Diabetes Differs from Non-Diabetic Adults

(2010) Nadja Larsen et al.   PLoS One

Impact of diet in shaping gut microbiota revealed by a comparative study in children from Europe and rural Africa

(2010) C. De Filippo et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The interaction of short-chain fatty acids with adipose tissue: relevance for prevention of type 2 diabetes

(2010) H. Roelofsen et al.   Beneficial Microbes

Human gut microbiome: the second genome of human body

(2010) Baoli Zhu et al.   Protein & Cell

Increased Risk of Type 2 Diabetes in Elderly Twins

(2009) P. Poulsen et al.   DIABETES

From the Triumvirate to the Ominous Octet: A New Paradigm for the Treatment of Type 2 Diabetes Mellitus

(2009) R. A. DeFronzo   DIABETES

Familial Risks for Type 2 Diabetes in Sweden

(2009) K. Hemminki et al.   DIABETES CARE

Skeletal Muscle Insulin Resistance Is the Primary Defect in Type 2 Diabetes

(2009) R. A. DeFronzo et al.   DIABETES CARE

The global diabetes epidemic as a consequence of lifestyle-induced low-grade inflammation

(2009) H. Kolb et al.   DIABETOLOGIA

High-Fat Diet Determines the Composition of the Murine Gut Microbiome Independently of Obesity

(2009) Marie A. Hildebrandt et al.   GASTROENTEROLOGY

Bacterial Community Variation in Human Body Habitats Across Space and Time

(2009) E. K. Costello et al.   SCIENCE

Ectopic lipids and organ function

(2008) Julia Szendroedi et al.   CURRENT OPINION IN LIPIDOLOGY

Strong Association Between Insulin Resistance in Liver and Skeletal Muscle in Non-Diabetic Subjects.

(2008) Muhammad A Abdul-Ghani et al.   DIABETIC MEDICINE

Probiotics improve high fat diet-induced hepatic steatosis and insulin resistance by increasing hepatic NKT cells

(2008) Xiong Ma et al.   JOURNAL OF HEPATOLOGY

Unknown

(2008) Herbert Tilg et al.   MOLECULAR MEDICINE

A core gut microbiome in obese and lean twins

(2008) Peter J. Turnbaugh et al.   NATURE

Effects of dietary fibers on disturbances clustered in the metabolic syndrome

(2007) Milagros Galisteo et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY