LETM1-Mediated K+ and Na+ Homeostasis Regulates Mitochondrial Ca2+ Efflux

Enjoy the Trip: Calcium in Mitochondria Back and Forth

(2016) Diego De Stefani et al.   Annual Review of Biochemistry

Mg2+ differentially regulates two modes of mitochondrial Ca2+ uptake in isolated cardiac mitochondria: implications for mitochondrial Ca2+ sequestration

(2016) Christoph A. Blomeyer et al.   JOURNAL OF BIOENERGETICS AND BIOMEMBRANES

Leucine zipper-EF-hand containing transmembrane protein 1 (LETM1) forms a Ca2+/H+ antiporter

(2016) Juan Shao et al.   Scientific Reports

The molecular era of the mitochondrial calcium uniporter

(2015) Kimberli J. Kamer et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Gene essentiality and synthetic lethality in haploid human cells

(2015) V. A. Blomen et al.   SCIENCE

Identification and characterization of essential genes in the human genome

(2015) T. Wang et al.   SCIENCE

Novel p53-dependent anticancer strategy by targeting iron signaling and BNIP3L-induced mitophagy

(2015) Nastasia Wilfinger et al.   Oncotarget

LETM1 haploinsufficiency causes mitochondrial defects in cells from humans with Wolf-Hirschhorn syndrome: implications for dissecting the underlying pathomechanisms in this condition

(2014) L. Hart et al.   Disease Models & Mechanisms

LETM1-dependent mitochondrial Ca2+ flux modulates cellular bioenergetics and proliferation

(2014) Patrick J. Doonan et al.   FASEB JOURNAL

NCLX Protein, but Not LETM1, Mediates Mitochondrial Ca2+Extrusion, Thereby Limiting Ca2+-induced NAD(P)H Production and Modulating Matrix Redox State

(2014) Umberto De Marchi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

LETM1 in mitochondrial cation transport

(2014) Karin Nowikovsky et al.   Frontiers in Physiology

Trypanosome Letm1 Protein Is Essential for Mitochondrial Potassium Homeostasis

(2013) Hassan Hashimi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Functional reconstitution of the mitochondrial Ca2+/H+antiporter Letm1

(2013) Ming-Feng Tsai et al.   JOURNAL OF GENERAL PHYSIOLOGY

Letm1, the mitochondrial Ca2+/H+ antiporter, is essential for normal glucose metabolism and alters brain function in Wolf-Hirschhorn syndrome

(2013) D. Jiang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Dynamic buffering of mitochondrial Ca2+ during Ca2+ uptake and Na+-induced Ca2+ release

(2012) Christoph A. Blomeyer et al.   JOURNAL OF BIOENERGETICS AND BIOMEMBRANES

Chemiosmotic coupling in oxidative and photosynthetic phosphorylation

(2011) Peter Mitchell   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

Integrative genomics identifies MCU as an essential component of the mitochondrial calcium uniporter

(2011) Joshua M. Baughman et al.   NATURE

A forty-kilodalton protein of the inner membrane is the mitochondrial calcium uniporter

(2011) Diego De Stefani et al.   NATURE

NCLX is an essential component of mitochondrial Na+/Ca2+ exchange

(2009) R. Palty et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Genome-Wide RNAi Screen Identifies Letm1 as a Mitochondrial Ca2+/H+ Antiporter

(2009) D. Jiang et al.   SCIENCE