Icariin, a Novel Blocker of Sodium and Calcium Channels, Eliminates Early and Delayed Afterdepolarizations, As Well As Triggered Activity, in Rabbit Cardiomyocytes
Published 2017 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Icariin, a Novel Blocker of Sodium and Calcium Channels, Eliminates Early and Delayed Afterdepolarizations, As Well As Triggered Activity, in Rabbit Cardiomyocytes
Authors
Keywords
-
Journal
Frontiers in Physiology
Volume 8, Issue -, Pages -
Publisher
Frontiers Media SA
Online
2017-05-29
DOI
10.3389/fphys.2017.00342
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Inhibition of late sodium current attenuates ionic arrhythmia mechanism in ventricular myocytes expressing LaminA-N195K mutation
- (2016) Yogananda S. Markandeya et al. HEART RHYTHM
- Impaired Inactivation of L-Type Ca2+ Current as a Potential Mechanism for Variable Arrhythmogenic Liability of HERG K+ Channel Blocking Drugs
- (2016) Jae Gon Kim et al. PLoS One
- Anti-Cancer Properties of the Naturally Occurring Aphrodisiacs: Icariin and Its Derivatives
- (2016) Hui-Li Tan et al. Frontiers in Pharmacology
- The Cardioprotective Effect of Icariin on Ischemia-Reperfusion Injury in Isolated Rat Heart: Potential Involvement of the PI3K-Akt Signaling Pathway
- (2015) Zunping Ke et al. Cardiovascular Therapeutics
- Protein kinase C and Ca2+-calmodulin-dependent protein kinase II mediate the enlarged reverseINCXinduced by ouabain-increased late sodium current in rabbit ventricular myocytes
- (2015) Ying Wu et al. EXPERIMENTAL PHYSIOLOGY
- Evolution of voltage-gated ion channels at the emergence of Metazoa
- (2015) Y. Moran et al. JOURNAL OF EXPERIMENTAL BIOLOGY
- Dependence of phase-2 reentry and repolarization dispersion on epicardial and transmural ionic heterogeneity: a simulation study
- (2014) Anat Maoz et al. EUROPACE
- Ventricular hypertrophy amplifies transmural dispersion of repolarization by preferentially increasing the late sodium current in endocardium
- (2014) Donglin Guo et al. JOURNAL OF ELECTROCARDIOLOGY
- Antioxidative protective effect of icariin on the FeSO4/H2O2-damaged human sperm based on confocal raman micro-spectroscopy
- (2014) Zhan-sen Huang et al. Journal of Huazhong University of Science and Technology-Medical Sciences
- Icariin attenuates angiotensin II-induced hypertrophy and apoptosis in H9c2 cardiomyocytes by inhibiting reactive oxygen species-dependent JNK and p38 pathways
- (2014) HENG ZHOU et al. Experimental and Therapeutic Medicine
- Larger late sodium current density as well as greater sensitivities to ATX II and ranolazine in rabbit left atrial than left ventricular myocytes
- (2013) Antao Luo et al. AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY
- Quinidine elicits proarrhythmic changes in ventricular repolarization and refractoriness in guinea-pig
- (2013) Oleg E. Osadchii CANADIAN JOURNAL OF PHYSIOLOGY AND PHARMACOLOGY
- Antiarrhythmic effects of the highly selective late sodium channel current blocker GS-458967
- (2013) Serge Sicouri et al. HEART RHYTHM
- Selective inhibition of late sodium current suppresses ventricular tachycardia and fibrillation in intact rat hearts
- (2013) Arash Pezhouman et al. HEART RHYTHM
- Arrhythmogenesis Toxicity of Aconitine Is Related to Intracellular Ca2+ Signals
- (2013) Yu-hong Zhou et al. International Journal of Medical Sciences
- Icariin Protects Rat Cardiac H9c2 Cells from Apoptosis by Inhibiting Endoplasmic Reticulum Stress
- (2013) Qiufang Zhang et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Inhibition of Th1/Th17 responses via suppression of STAT1 and STAT3 activation contributes to the amelioration of murine experimental colitis by a natural flavonoid glucoside icariin
- (2012) Feifei Tao et al. BIOCHEMICAL PHARMACOLOGY
- Persistent sodium current and Na+/H+ exchange contributes to the augmentation of the reverse Na+/Ca2+ exchange during hypoxia or acute ischemia in ventricular myocytes
- (2012) Qiong Tang et al. PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY
- Calmodulin kinase II and protein kinase C mediate the effect of increased intracellular calcium to augment late sodium current in rabbit ventricular myocytes
- (2011) Jihua Ma et al. AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY
- Icariin induces apoptosis in mouse MLTC-10 Leydig tumor cells through activation of the mitochondrial pathway and down-regulation of the expression of piwil4
- (2011) Yi Xie INTERNATIONAL JOURNAL OF ONCOLOGY
- Icariin attenuates cardiac remodelling through down-regulating myocardial apoptosis and matrix metalloproteinase activity in rats with congestive heart failure
- (2011) Yao-Hong Song et al. JOURNAL OF PHARMACY AND PHARMACOLOGY
- Neuroprotective effects of icariin on corticosterone-induced apoptosis in primary cultured rat hippocampal neurons
- (2010) Baojun Liu et al. BRAIN RESEARCH
- Icariin attenuates LPS-induced acute inflammatory responses: Involvement of PI3K/Akt and NF-κB signaling pathway
- (2010) Chang-Qing Xu et al. EUROPEAN JOURNAL OF PHARMACOLOGY
- Icariin induces mouse embryonic stem cell differentiation into beating functional cardiomyocytes
- (2010) Xiaodong Sun et al. MOLECULAR AND CELLULAR BIOCHEMISTRY
- Self-augmentation of the lengthening of repolarization is related to the shape of the cardiac action potential: implications for reverse rate dependency
- (2009) László Virág et al. BRITISH JOURNAL OF PHARMACOLOGY
- Dispersion of repolarization and arrhythmogenesis
- (2009) Ruben Coronel et al. HEART RHYTHM
- L-type Ca2+ current in ventricular cardiomyocytes
- (2009) Jean-Pierre Benitah et al. JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY
- Intracellular calcium modulation of voltage-gated sodium channels in ventricular myocytes
- (2008) Simona Casini et al. CARDIOVASCULAR RESEARCH
- Electrophysiological Consequences of Acute Regional Ischemia/Reperfusion in Neonatal Rat Ventricular Myocyte Monolayers
- (2008) Carlos de Diego et al. CIRCULATION
- Calcium-Handling Abnormalities Underlying Atrial Arrhythmogenesis and Contractile Dysfunction in Dogs With Congestive Heart Failure
- (2008) Yung-Hsin Yeh et al. Circulation-Arrhythmia and Electrophysiology
Discover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversationCreate your own webinar
Interested in hosting your own webinar? Check the schedule and propose your idea to the Peeref Content Team.
Create Now