Anti-Cancer Properties of the Naturally Occurring Aphrodisiacs: Icariin and Its Derivatives
Published 2016 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Anti-Cancer Properties of the Naturally Occurring Aphrodisiacs: Icariin and Its Derivatives
Authors
Keywords
-
Journal
Frontiers in Pharmacology
Volume 7, Issue -, Pages -
Publisher
Frontiers Media SA
Online
2016-06-30
DOI
10.3389/fphar.2016.00191
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- TPGS/Phospholipids Mixed Micelles for Delivery of Icariside II to Multidrug-Resistant Breast Cancer
- (2016) Jie Song et al. INTEGRATIVE CANCER THERAPIES
- Icariside II inhibits the EMT of NSCLC cells in inflammatory microenvironment via down-regulation of Akt/NF-κB signaling pathway
- (2016) Jie Song et al. MOLECULAR CARCINOGENESIS
- Nerolidol: A Sesquiterpene Alcohol with Multi-Faceted Pharmacological and Biological Activities
- (2016) Weng-Keong Chan et al. MOLECULES
- Gynura procumbens: An Overview of the Biological Activities
- (2016) Hui-Li Tan et al. Frontiers in Pharmacology
- Icariin displays anticancer activity against human esophageal cancer cells via regulating endoplasmic reticulum stress-mediated apoptotic signaling
- (2016) Chongxi Fan et al. Scientific Reports
- 225PA novel anti-cancer agent icaritin suppresses hepatocellular carcinoma initiation and malignant growth through the IL-6/Jak2/Stat3 pathway
- (2015) H. Zhao ANNALS OF ONCOLOGY
- Activation of endoplasmic reticulum stress is involved in the activity of icariin against human lung adenocarcinoma cells
- (2015) Shouyin Di et al. APOPTOSIS
- Icariin Enhances Cytotoxicity of Doxorubicin in Human Multidrug-Resistant Osteosarcoma Cells by Inhibition of ABCB1 and Down-Regulation of the PI3K/Akt Pathway
- (2015) Zhendong Wang et al. BIOLOGICAL & PHARMACEUTICAL BULLETIN
- Icariside II-induced mitochondrion and lysosome mediated apoptosis is counterbalanced by an autophagic salvage response in hepatoblastoma
- (2015) Ya-di Geng et al. CANCER LETTERS
- A novel prostate cancer therapeutic strategy using icaritin-activated arylhydrocarbon-receptor to co-target androgen receptor and its splice variants
- (2015) Feng Sun et al. CARCINOGENESIS
- Arsenic Trioxide and Icariin Show Synergistic Anti-leukemic Activity
- (2015) Zhi Wang et al. CELL BIOCHEMISTRY AND BIOPHYSICS
- Icaritin Sensitizes Human Glioblastoma Cells to TRAIL-Induced Apoptosis
- (2015) Hongxing Han et al. CELL BIOCHEMISTRY AND BIOPHYSICS
- Icaritin inhibits the invasion and epithelial-to-mesenchymal transition of glioblastoma cells by targeting EMMPRIN via PTEN/AKt/HIF-1αsignalling
- (2015) Bo Xu et al. CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY
- Optimization and anticancer activity in vitro and in vivo of baohuoside I incorporated into mixed micelles based on lecithin and Solutol HS 15
- (2015) Hong-mei Yan et al. DRUG DELIVERY
- Synthesis and cancer cell growth inhibitory activity of icaritin derivatives
- (2015) Chen Wang et al. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
- Traditional Uses, Phytochemistry, and Bioactivities ofCananga odorata(Ylang-Ylang)
- (2015) Loh Teng Hern Tan et al. Evidence-based Complementary and Alternative Medicine
- Targeting Apoptosis and Multiple Signaling Pathways with Icariside II in Cancer Cells
- (2015) Muhammad Khan et al. International Journal of Biological Sciences
- Myeloid-derived suppressor cells in the tumor microenvironment: expect the unexpected
- (2015) Douglas Marvel et al. JOURNAL OF CLINICAL INVESTIGATION
- Elephantopus scaber induces apoptosis through ROS-dependent mitochondrial signaling pathway in HCT116 human colorectal carcinoma cells
- (2015) Chim Kei Chan et al. JOURNAL OF ETHNOPHARMACOLOGY
- Icaritin induces lytic cytotoxicity in extranodal NK/T-cell lymphoma
- (2015) Ting Wu et al. JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH
- Anti-Androgenic Activity of Icarisid II from Epimedium Herb in Prostate Cancer LNCaP Cells
- (2015) Yoko MIURA et al. JOURNAL OF NUTRITIONAL SCIENCE AND VITAMINOLOGY
- Potent PPARγ Ligands from Swietenia macrophylla Are Capable of Stimulating Glucose Uptake in Muscle Cells
- (2015) Wai Lau et al. MOLECULES
- Icaritin acts synergistically with epirubicin to suppress bladder cancer growth through inhibition of autophagy
- (2015) XIU-WU PAN et al. ONCOLOGY REPORTS
- Icaritin protects against oxidative stress-induced injury in cardiac H9c2 cells via Akt/Nrf2/HO-1 and calcium signalling pathways
- (2015) Si Wan Lei et al. Journal of Functional Foods
- SMEAF attenuates the production of pro-inflammatory mediators through the inactivation of Akt-dependent NF-κB, p38 and ERK1/2 pathways in LPS-stimulated BV-2 microglial cells
- (2015) Hadi Supriady et al. Journal of Functional Foods
- Icariside II ameliorates diabetic nephropathy in streptozotocin-induced diabetic rats
- (2015) Hongen Lei et al. Drug Design Development and Therapy
- Icaritin suppresses multiple myeloma, by inhibiting IL-6/JAK2/STAT3
- (2015) Shicong Zhu et al. Oncotarget
- Icaritin suppresses the proliferation of human osteosarcoma cells in vitro by increasing apoptosis and decreasing MMP expression
- (2014) Xiao-fang Wang et al. ACTA PHARMACOLOGICA SINICA
- Baohuoside I Suppresses Invasion of Cervical and Breast Cancer Cells through the Downregulation of CXCR4 Chemokine Receptor Expression
- (2014) Buyun Kim et al. BIOCHEMISTRY
- Icariin Enhances Radiosensitivity of Colorectal Cancer Cells by Suppressing NF-κB Activity
- (2014) Yi Zhang et al. CELL BIOCHEMISTRY AND BIOPHYSICS
- Icariin-Mediated Inhibition of NF-κB Activity Enhances the In Vitro and In Vivo Antitumour Effect of 5-Fluorouracil in Colorectal Cancer
- (2014) De-Bing Shi et al. CELL BIOCHEMISTRY AND BIOPHYSICS
- Synergistic Anti-Cancer Effects of Icariin and Temozolomide in Glioblastoma
- (2014) Lijuan Yang et al. CELL BIOCHEMISTRY AND BIOPHYSICS
- Blockade of epidermal growth factor receptor/mammalian target of rapamycin pathway by Icariside II results in reduced cell proliferation of osteosarcoma cells
- (2014) Ya-di Geng et al. FOOD AND CHEMICAL TOXICOLOGY
- Swietenia macrophylla King induces mitochondrial-mediated apoptosis through p53 upregulation in HCT116 colorectal carcinoma cells
- (2014) Bey Hing Goh et al. JOURNAL OF ETHNOPHARMACOLOGY
- Anticancer effect of icaritin on human lung cancer cells through inducing s phase cell cycle arrest and apoptosis
- (2014) Qian Zheng et al. Journal of Huazhong University of Science and Technology-Medical Sciences
- Icariside II inhibits cell proliferation and induces cell cycle arrest through the ROS-p38-p53 signaling pathway in A375 human melanoma cells
- (2014) JINFENG WU et al. Molecular Medicine Reports
- Anticancer agent icaritin induces apoptosis through caspase-dependent pathways in human hepatocellular carcinoma cells
- (2014) LI SUN et al. Molecular Medicine Reports
- Effects of Icariin on Reproductive Functions in Male Rats
- (2014) Maoxin Chen et al. MOLECULES
- Combined Treatment withEpimedium koreanumNakai Extract and Gefitinib Overcomes Drug Resistance Caused by T790M Mutation in Non-Small Cell Lung Cancer Cells
- (2014) Jie Song et al. NUTRITION AND CANCER-AN INTERNATIONAL JOURNAL
- Synergistic inhibitory effect of Icariside II with Icaritin from Herba Epimedii on pre-osteoclastic RAW264.7 cell growth
- (2014) Yan-Qiu Liu et al. PHYTOMEDICINE
- Cytotoxic Effect of Icaritin and Its Mechanisms in Inducing Apoptosis in Human Burkitt Lymphoma Cell Line
- (2014) Zi-Jian Li et al. Biomed Research International
- Cancer Stem Cells and Their Mechanism of Chemo-Radiation Resistance
- (2014) Yonghyun Kim et al. International Journal of Stem Cells
- Icariin Synergizes with Arsenic Trioxide to Suppress Human Hepatocellular Carcinoma
- (2013) Wen Li et al. CELL BIOCHEMISTRY AND BIOPHYSICS
- Honey as a Potential Natural Anticancer Agent: A Review of Its Mechanisms
- (2013) Sarfraz Ahmed et al. Evidence-based Complementary and Alternative Medicine
- Icaritin induces AML cell apoptosis via the MAPK/ERK and PI3K/AKT signal pathways
- (2013) Qihui Li et al. INTERNATIONAL JOURNAL OF HEMATOLOGY
- Icariside II induces apoptosis via inhibition of the EGFR pathways in A431 human epidermoid carcinoma cells
- (2013) JINFENG WU et al. Molecular Medicine Reports
- Icaritin reverses multidrug resistance of HepG2/ADR human hepatoma cells via downregulation of MDR1 and P-glycoprotein expression
- (2013) LI SUN et al. Molecular Medicine Reports
- Icariside II Induces Apoptosis of Melanoma Cells Through the Downregulation of Survival Pathways
- (2013) Jinfeng Wu et al. NUTRITION AND CANCER-AN INTERNATIONAL JOURNAL
- Selective Estrogen Receptor Modulator Effects of Epimedium Extracts on Breast Cancer and Uterine Growth in Nude Mice
- (2013) Inthrani Indran et al. PLANTA MEDICA
- Icaritin Synergistically Enhances the Radiosensitivity of 4T1 Breast Cancer Cells
- (2013) Jinsheng Hong et al. PLoS One
- Icaritin Inhibits JAK/STAT3 Signaling and Growth of Renal Cell Carcinoma
- (2013) Shasha Li et al. PLoS One
- Icariin potentiates the antitumor activity of gemcitabine in gallbladder cancer by suppressing NF-κB
- (2012) Dian-cai Zhang et al. ACTA PHARMACOLOGICA SINICA
- Induction of Apoptosis by Icariside II through Extrinsic and Intrinsic Signaling Pathways in Human Breast Cancer MCF7 Cells
- (2012) Chaoqing HUANG et al. BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY
- A novel prenylflavone restricts breast cancer cell growth through AhR-mediated destabilization of ERα protein
- (2012) Chi Tze Tiong et al. CARCINOGENESIS
- Reactive oxygen species-mediated mitochondrial pathway is involved in Baohuoside I-induced apoptosis in human non-small cell lung cancer
- (2012) Jie Song et al. CHEMICO-BIOLOGICAL INTERACTIONS
- Icariside II potentiates paclitaxel-induced apoptosis in human melanoma A375 cells by inhibiting TLR4 signaling pathway
- (2012) Jinfeng Wu et al. FOOD AND CHEMICAL TOXICOLOGY
- Aqueous Fraction of Nephelium ramboutan-ake Rind Induces Mitochondrial-Mediated Apoptosis in HT-29 Human Colorectal Adenocarcinoma Cells
- (2012) Chim Kei Chan et al. MOLECULES
- Cancer stem cells and drug resistance: the potential of nanomedicine
- (2012) Serguei Vinogradov et al. Nanomedicine
- Anti-Angiogenic Activity ofHerba Epimediion Zebrafish EmbryosIn Vivoand HUVECsIn Vitro
- (2012) Xiaobin Yu et al. PHYTOTHERAPY RESEARCH
- Icariside II Induces Apoptosis in U937 Acute Myeloid Leukemia Cells: Role of Inactivation of STAT3-Related Signaling
- (2012) Sang-Hun Kang et al. PLoS One
- Icaritin, an Exogenous Phytomolecule, Enhances Osteogenesis but Not Angiogenesis—An In Vitro Efficacy Study
- (2012) Dong Yao et al. PLoS One
- Statistically designed enzymatic hydrolysis of an icariin/β-cyclodextrin inclusion complex optimized for production of icaritin
- (2012) Xin Jin et al. Acta Pharmaceutica Sinica B
- Chemosensitization of tumors by resveratrol
- (2011) Subash C. Gupta et al. Annals of the New York Academy of Sciences
- An anticancer agent icaritin induces sustained activation of the extracellular signal-regulated kinase (ERK) pathway and inhibits growth of breast cancer cells
- (2011) YuMing Guo et al. EUROPEAN JOURNAL OF PHARMACOLOGY
- Icariin and its derivative, ICT, exert anti-inflammatory, anti-tumor effects, and modulate myeloid derived suppressive cells (MDSCs) functions
- (2011) Junmin Zhou et al. INTERNATIONAL IMMUNOPHARMACOLOGY
- Icariin induces apoptosis in mouse MLTC-10 Leydig tumor cells through activation of the mitochondrial pathway and down-regulation of the expression of piwil4
- (2011) Yi Xie INTERNATIONAL JOURNAL OF ONCOLOGY
- Antitumor Activity of Artemisinin and Its Derivatives: From a Well-Known Antimalarial Agent to a Potential Anticancer Drug
- (2011) Maria P. Crespo-Ortiz et al. JOURNAL OF BIOMEDICINE AND BIOTECHNOLOGY
- The genus Epimedium: An ethnopharmacological and phytochemical review
- (2011) Huiping Ma et al. JOURNAL OF ETHNOPHARMACOLOGY
- The flavonoid Baohuoside-I inhibits cell growth and downregulates survivin and cyclin D1 expression in esophageal carcinoma via β-catenin-dependent signaling
- (2011) Baoen Shan ONCOLOGY REPORTS
- Icariin induces the Expression of Toll-like Receptor 9 in Ana-1 Murine Macrophages
- (2011) Li Li et al. PHYTOTHERAPY RESEARCH
- Icaritin Causes Sustained ERK1/2 Activation and Induces Apoptosis in Human Endometrial Cancer Cells
- (2011) Jing-Shan Tong et al. PLoS One
- Icaritin Shows Potent Anti-Leukemia Activity on Chronic Myeloid Leukemia In Vitro and In Vivo by Regulating MAPK/ERK/JNK and JAK2/STAT3 /AKT Signalings
- (2011) Jian feng Zhu et al. PLoS One
- Icariin and its Derivative Icariside II Extend Healthspan via Insulin/IGF-1 Pathway in C. elegans
- (2011) Wai-Jiao Cai et al. PLoS One
- Icariin, a natural flavonol glycoside, induces apoptosis in human hepatoma SMMC-7721 cells via a ROS/JNK-dependent mitochondrial pathway
- (2010) Songgang Li et al. CANCER LETTERS
- Icariin exterts negative effects on human gastric cancer cell invasion and migration by vasodilator-stimulated phosphoprotein via Rac1 pathway
- (2010) Yongping Wang et al. EUROPEAN JOURNAL OF PHARMACOLOGY
- Icariin attenuates LPS-induced acute inflammatory responses: Involvement of PI3K/Akt and NF-κB signaling pathway
- (2010) Chang-Qing Xu et al. EUROPEAN JOURNAL OF PHARMACOLOGY
- Janus activated kinase 2/signal transducer and activator of transcription 3 pathway mediates icariside II-induced apoptosis in U266 multiple myeloma cells
- (2010) Sun-Hee Kim et al. EUROPEAN JOURNAL OF PHARMACOLOGY
- Icaritin Induces Apoptosis of HepG2 Cells via the JNK1 Signaling Pathway Independent of the Estrogen Receptor
- (2010) Jun He et al. PLANTA MEDICA
- The Role of Traditional Chinese Herbal Medicines in Cancer Therapy – from TCM Theory to Mechanistic Insights
- (2010) W. Hsiao et al. PLANTA MEDICA
- Anti-Proliferative Efficacy of Icariin on HepG2 Hepatoma and Its Possible Mechanism of Action
- (2009) Jin-Xia Yang et al. AMERICAN JOURNAL OF CHINESE MEDICINE
- Synthesis and antimultidrug resistance evaluation of icariin and its derivatives
- (2009) Dong-Fang Liu et al. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
- Cyclooxygenase-2/prostaglandin E2 pathway mediates icariside II induced apoptosis in human PC-3 prostate cancer cells
- (2009) Keun-Sung Lee et al. CANCER LETTERS
- The COX-2/PGE2 pathway: key roles in the hallmarks of cancer and adaptation to the tumour microenvironment
- (2009) A. Greenhough et al. CARCINOGENESIS
- Icariin inhibits beta-amyloid peptide segment 25–35 induced expression of β-secretase in rat hippocampus
- (2009) Jing Nie et al. EUROPEAN JOURNAL OF PHARMACOLOGY
- Preparation of icariside II from icariin by enzymatic hydrolysis method
- (2009) Quan Xia et al. FITOTERAPIA
- Cancer chemotherapy: not only a direct cytotoxic effect, but also an adjuvant for antitumor immunity
- (2008) Cédric Ménard et al. CANCER IMMUNOLOGY IMMUNOTHERAPY
- Simple and sensitive liquid chromatography–tandem mass spectrometry assay for simultaneous measurement of five Epimedium prenylflavonoids in rat sera
- (2008) Ping Shen et al. JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES
- Antiosteoporotic chemical constituents from Er-Xian Decoction, a traditional Chinese herbal formula
- (2008) Luping Qin et al. JOURNAL OF ETHNOPHARMACOLOGY
- The role of VASP in regulation of cAMP- and Rac 1-mediated endothelial barrier stabilization
- (2007) N. Schlegel et al. AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY
- Icariside II from Epimedium koreanum inhibits hypoxia-inducible factor-1α in human osteosarcoma cells
- (2007) Hwa Jung Choi et al. EUROPEAN JOURNAL OF PHARMACOLOGY
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreFind the ideal target journal for your manuscript
Explore over 38,000 international journals covering a vast array of academic fields.
Search