RNA-Seq Analysis of Microglia Reveals Time-Dependent Activation of Specific Genetic Programs following Spinal Cord Injury

Arginase-1 is expressed exclusively by infiltrating myeloid cells in CNS injury and disease

(2016) Andrew D. Greenhalgh et al.   BRAIN BEHAVIOR AND IMMUNITY

Human glioblastoma-associated microglia/monocytes express a distinct RNA profile compared to human control and murine samples

(2016) Frank Szulzewsky et al.   GLIA

Spinal cord injury induces astroglial conversion towards neuronal lineage

(2016) Harun Najib Noristani et al.   Molecular Neurodegeneration

New insights into the multidimensional concept of macrophage ontogeny, activation and function

(2016) Florent Ginhoux et al.   NATURE IMMUNOLOGY

A polarizing question: do M1 and M2 microglia exist?

(2016) Richard M Ransohoff   NATURE NEUROSCIENCE

New tools for studying microglia in the mouse and human CNS

(2016) Mariko L. Bennett et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Astrocyte-to-neuron conversion induced by spinal cord injury

(2016) Harun Najib Noristani et al.   Oncotarget

Brca1 is expressed in human microglia and is dysregulated in human and animal model of ALS

(2015) Harun Najib Noristani et al.   Molecular Neurodegeneration

Pronounced species divergence in corticospinal tract reorganization and functional recovery after lateralized spinal cord injury favors primates

(2015) Lucia Friedli et al.   Science Translational Medicine

Correlation of in vivo and ex vivo1H-MRI with histology in two severities of mouse spinal cord injury

(2015) Harun N. Noristani et al.   Frontiers in Neuroanatomy

Environment Drives Selection and Function of Enhancers Controlling Tissue-Specific Macrophage Identities

(2014) David Gosselin et al.   CELL

Global gene expression analysis following spinal cord injury in non-human primates

(2014) Soraya Nishimura et al.   EXPERIMENTAL NEUROLOGY

Characterization of the expression and inflammatory activity of NADPH oxidase after spinal cord injury

(2014) S. J. Cooney et al.   FREE RADICAL RESEARCH

Transcriptome-Based Network Analysis Reveals a Spectrum Model of Human Macrophage Activation

(2014) Jia Xue et al.   IMMUNITY

An RNA-Sequencing Transcriptome and Splicing Database of Glia, Neurons, and Vascular Cells of the Cerebral Cortex

(2014) Y. Zhang et al.   JOURNAL OF NEUROSCIENCE

Differences in the Phagocytic Response of Microglia and Peripheral Macrophages after Spinal Cord Injury and Its Effects on Cell Death

(2014) A. D. Greenhalgh et al.   JOURNAL OF NEUROSCIENCE

TNF and Increased Intracellular Iron Alter Macrophage Polarization to a Detrimental M1 Phenotype in the Injured Spinal Cord

(2014) Antje Kroner et al.   NEURON

Colony-Stimulating Factor 1 Receptor Signaling Is Necessary for Microglia Viability, Unmasking a Microglia Progenitor Cell in the Adult Brain

(2014) Monica R.P. Elmore et al.   NEURON

Role of BRCA1 in brain development

(2014) Gerald M. Pao et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

BRCA1 regulates insulin-like growth factor 1 receptor levels in ovarian cancer

(2014) BO LIU et al.   Oncology Letters

Mobilisation of the splenic monocyte reservoir and peripheral CX3CR1 deficiency adversely affects recovery from spinal cord injury

(2013) Linda V. Blomster et al.   EXPERIMENTAL NEUROLOGY

Unique transcriptome signature of mouse microglia

(2013) Clara Beutner et al.   GLIA

Astroglial IFITM3 mediates neuronal impairments following neonatal immune challenge in mice

(2013) Daisuke Ibi et al.   GLIA

Recruitment of Beneficial M2 Macrophages to Injured Spinal Cord Is Orchestrated by Remote Brain Choroid Plexus

(2013) Ravid Shechter et al.   IMMUNITY

A short review on the implications of base excision repair pathway for neurons: Relevance to neurodegenerative diseases

(2013) Anil K. Mantha et al.   MITOCHONDRION

Identification of a unique TGF-β–dependent molecular and functional signature in microglia

(2013) Oleg Butovsky et al.   NATURE NEUROSCIENCE

The microglial sensome revealed by direct RNA sequencing

(2013) Suzanne E Hickman et al.   NATURE NEUROSCIENCE

Phenotypic transition of microglia into astrocyte-like cells associated with disease onset in a model of inherited ALS

(2013) Emiliano Trias et al.   Frontiers in Cellular Neuroscience

Microglia, seen from the CX3CR1 angle

(2013) Yochai Wolf et al.   Frontiers in Cellular Neuroscience

Animal models of axon regeneration after spinal cord injury

(2013) Do-Hun Lee et al.   Neuroscience Bulletin

A Neurodegeneration-Specific Gene-Expression Signature of Acutely Isolated Microglia from an Amyotrophic Lateral Sclerosis Mouse Model

(2013) Isaac M. Chiu et al.   Cell Reports

Transcriptome analysis of amoeboid and ramified microglia isolated from the corpus callosum of rat brain

(2012) Rangarajan Parakalan et al.   BMC NEUROSCIENCE

Transformation from a neuroprotective to a neurotoxic microglial phenotype in a mouse model of ALS

(2012) Bing Liao et al.   EXPERIMENTAL NEUROLOGY

Ly6C+Ly6G−Myeloid-derived suppressor cells play a critical role in the resolution of acute inflammation and the subsequent tissue repair process after spinal cord injury

(2012) Hirokazu Saiwai et al.   JOURNAL OF NEUROCHEMISTRY

Genomic Analysis of Reactive Astrogliosis

(2012) J. L. Zamanian et al.   JOURNAL OF NEUROSCIENCE

Gene-expression profiles and transcriptional regulatory pathways that underlie the identity and diversity of mouse tissue macrophages

(2012) Emmanuel L Gautier et al.   NATURE IMMUNOLOGY

Early Functional Deficit and Microglial Disturbances in a Mouse Model of Amyotrophic Lateral Sclerosis

(2012) Yannick Nicolas Gerber et al.   PLoS One

Hypothesis: Are Neoplastic Macrophages/Microglia Present in Glioblastoma Multiforme?

(2011) Leanne C Huysentruyt et al.   ASN Neuro

Tumor suppressor genes and ROS: complex networks of interactions

(2011) Beyza Vurusaner et al.   FREE RADICAL BIOLOGY AND MEDICINE

Identification of a microglia phenotype supportive of remyelination

(2011) Marta Olah et al.   GLIA

Deficient CX3CR1 Signaling Promotes Recovery after Mouse Spinal Cord Injury by Limiting the Recruitment and Activation of Ly6Clo/iNOS+ Macrophages

(2011) D. J. Donnelly et al.   JOURNAL OF NEUROSCIENCE

Compromised CDK1 activity sensitizes BRCA-proficient cancers to PARP inhibition

(2011) Neil Johnson et al.   NATURE MEDICINE

Repertoire of microglial and macrophage responses after spinal cord injury

(2011) Samuel David et al.   NATURE REVIEWS NEUROSCIENCE

Physiology of Microglia

(2011) Helmut Kettenmann et al.   PHYSIOLOGICAL REVIEWS

In Situ Dividing and Phagocytosing Retinal Microglia Express Nestin, Vimentin, and NG2 In Vivo

(2011) Stefanie G. Wohl et al.   PLoS One

Serotonin fibre sprouting and increase in serotonin transporter immunoreactivity in the CA1 area of hippocampus in a triple transgenic mouse model of Alzheimer’s disease

(2010) H. N. Noristani et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Anti-IL-6-receptor antibody promotes repair of spinal cord injury by inducing microglia-dominant inflammation

(2010) Masahiko Mukaino et al.   EXPERIMENTAL NEUROLOGY

Progranulin is Neurotrophic In Vivo and Protects against a Mutant TDP-43 Induced Axonopathy

(2010) Angela S. Laird et al.   PLoS One

Increase in the density of resting microglia precedes neuritic plaque formation and microglial activation in a transgenic model of Alzheimer's disease

(2010) J J Rodríguez et al.   Cell Death & Disease

Prediction of qualitative outcome of oligonucleotide microarray hybridization by measurement of RNA integrity using the 2100 Bioanalyzer™ capillary electrophoresis system

(2009) Philipp Kiewe et al.   ANNALS OF HEMATOLOGY

A role for SOX2 in the generation of microtubule-associated protein 2-positive cells from microglia

(2009) Hideki Nonaka et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Progranulin is expressed within motor neurons and promotes neuronal cell survival

(2009) Cara L Ryan et al.   BMC NEUROSCIENCE

Increased Synthesis of Spermidine as a Result of Upregulation of Arginase I Promotes Axonal Regeneration in Culture and In Vivo

(2009) K. Deng et al.   JOURNAL OF NEUROSCIENCE

Microglia Protect Neurons against Ischemia by Synthesis of Tumor Necrosis Factor

(2009) K. L. Lambertsen et al.   JOURNAL OF NEUROSCIENCE

Identification of Two Distinct Macrophage Subsets with Divergent Effects Causing either Neurotoxicity or Regeneration in the Injured Mouse Spinal Cord

(2009) K. A. Kigerl et al.   JOURNAL OF NEUROSCIENCE

Infiltrating Blood-Derived Macrophages Are Vital Cells Playing an Anti-inflammatory Role in Recovery from Spinal Cord Injury in Mice

(2009) Ravid Shechter et al.   PLOS MEDICINE

A molecular pathway involved in the generation of microtubule-associated protein 2-positive cells from microglia

(2008) Tetsuhiro Niidome et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Regulation of interleukin-1β by the interleukin-1 receptor antagonist in the glutamate-injured spinal cord: Endogenous neuroprotection

(2008) Song Liu et al.   BRAIN RESEARCH

A Transcriptome Database for Astrocytes, Neurons, and Oligodendrocytes: A New Resource for Understanding Brain Development and Function

(2008) J. D. Cahoy et al.   JOURNAL OF NEUROSCIENCE