Role of APP Interactions with Heterotrimeric G Proteins: Physiological Functions and Pathological Consequences
Published 2017 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Role of APP Interactions with Heterotrimeric G Proteins: Physiological Functions and Pathological Consequences
Authors
Keywords
-
Journal
Frontiers in Molecular Neuroscience
Volume 10, Issue -, Pages -
Publisher
Frontiers Media SA
Online
2017-01-31
DOI
10.3389/fnmol.2017.00003
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Alzheimer-related protein APL-1 modulates lifespan through heterochronic gene regulation inCaenorhabditis elegans
- (2016) Collin Y. Ewald et al. AGING CELL
- Progress and prospects for structural studies of transmembrane interactions in single-spanning receptors
- (2016) Raphael Trenker et al. CURRENT OPINION IN STRUCTURAL BIOLOGY
- Go is required for the release of IL-8 and TNF-α, but not degranulation in human mast cells
- (2016) Yangyang Yu et al. EUROPEAN JOURNAL OF PHARMACOLOGY
- Evidence For and Against a Pathogenic Role of Reduced γ-Secretase Activity in Familial Alzheimer’s Disease
- (2016) Tanya Jayne et al. JOURNAL OF ALZHEIMERS DISEASE
- Increased Amyloid Precursor Protein and Tau Expression Manifests as Key Secondary Cell Death in Chronic Traumatic Brain Injury
- (2016) Sandra A. Acosta et al. JOURNAL OF CELLULAR PHYSIOLOGY
- Alzheimer’s disease in people with Down’s syndrome: the prospects for and the challenges of developing preventative treatments
- (2016) Paula Castro et al. JOURNAL OF NEUROLOGY
- Manduca Contactin Regulates Amyloid Precursor Protein-Dependent Neuronal Migration
- (2016) Jenna M. Ramaker et al. JOURNAL OF NEUROSCIENCE
- APP Receptor? To Be or Not To Be
- (2016) Carole Deyts et al. TRENDS IN PHARMACOLOGICAL SCIENCES
- Signals and Receptors
- (2016) Carl-Henrik Heldin et al. Cold Spring Harbor Perspectives in Biology
- Loss of presenilin function is associated with a selective gain of APP function
- (2016) Carole Deyts et al. eLife
- The Neuroprotective Properties of the Amyloid Precursor Protein Following Traumatic Brain Injury
- (2016) Stephanie Plummer et al. Aging and Disease
- Amyloid Precursor Proteins Are Dynamically Trafficked and Processed during Neuronal Development
- (2016) Jenna M. Ramaker et al. Frontiers in Molecular Neuroscience
- Analysis of Amyloid Precursor Protein Function in Drosophila melanogaster
- (2016) Marlène Cassar et al. Frontiers in Molecular Neuroscience
- Neuronal migration during development and the amyloid precursor protein
- (2016) Philip F Copenhaver et al. Current Opinion in Insect Science
- Amyloid Proteins and Their Role in Multiple Sclerosis. Considerations in the Use of Amyloid-PET Imaging
- (2016) Jordi A. Matías-Guiu et al. Frontiers in Neurology
- Soluble amyloid precursor protein alpha inhibits tau phosphorylation through modulation of GSK3β signaling pathway
- (2015) Juan Deng et al. JOURNAL OF NEUROCHEMISTRY
- The Full-Length Form of the Drosophila Amyloid Precursor Protein Is Involved in Memory Formation
- (2015) I. Bourdet et al. JOURNAL OF NEUROSCIENCE
- Decoding the molecular mechanisms of neuronal migration using in utero electroporation
- (2015) Hidenori Tabata et al. Medical Molecular Morphology
- Contactin-4 Mediates Axon-Target Specificity and Functional Development of the Accessory Optic System
- (2015) Jessica A. Osterhout et al. NEURON
- The multifaceted nature of amyloid precursor protein and its proteolytic fragments: friends and foes
- (2014) Hoang S. Nhan et al. ACTA NEUROPATHOLOGICA
- Glycogen Synthase Kinase-β3 in Ischemic Neuronal Death
- (2014) Pradeep Hanumanthappa et al. CURRENT NEUROVASCULAR RESEARCH
- The Crystal Structure of Netrin-1 in Complex with DCC Reveals the Bifunctionality of Netrin-1 As a Guidance Cue
- (2014) Lorenzo I. Finci et al. NEURON
- Holo-APP and G-protein-mediated signaling are required for sAPPα-induced activation of the Akt survival pathway
- (2014) N Milosch et al. Cell Death & Disease
- APP Homodimers Transduce an Amyloid-β-Mediated Increase in Release Probability at Excitatory Synapses
- (2014) Hilla Fogel et al. Cell Reports
- GSK-3 signaling in developing cortical neurons is essential for radial migration and dendritic orientation
- (2014) Meghan Morgan-Smith et al. eLife
- GSK-3β, a pivotal kinase in Alzheimer disease
- (2014) MarÃa Llorens-MarÃtin et al. Frontiers in Molecular Neuroscience
- Systematic Evaluation of Candidate Ligands Regulating Ectodomain Shedding of Amyloid Precursor Protein
- (2013) Heather C. Rice et al. BIOCHEMISTRY
- Redundancy and divergence in the amyloid precursor protein family
- (2013) S. Ali M. Shariati et al. FEBS LETTERS
- Amyloid Precursor Proteins Interact with the Heterotrimeric G Protein Go in the Control of Neuronal Migration
- (2013) J. M. Ramaker et al. JOURNAL OF NEUROSCIENCE
- Switching Responses: Spatial and Temporal Regulators of Axon Guidance
- (2013) Andrew Kaplan et al. MOLECULAR NEUROBIOLOGY
- Pancortins interact with amyloid precursor protein and modulate cortical cell migration
- (2012) H. C. Rice et al. DEVELOPMENT
- Novel G S-Protein Signaling Associated with Membrane-Tethered Amyloid Precursor Protein Intracellular Domain
- (2012) C. Deyts et al. JOURNAL OF NEUROSCIENCE
- Amyloid precursor proteins are protective in Drosophila models of progressive neurodegeneration
- (2012) Jill S. Wentzell et al. NEUROBIOLOGY OF DISEASE
- The secreted Alzheimer-related amyloid precursor protein fragment has an essential role inC. elegans
- (2012) Collin Y. Ewald et al. Prion
- Semaphorin Signaling in Vertebrate Neural Circuit Assembly
- (2012) Yutaka Yoshida Frontiers in Molecular Neuroscience
- Neurobiological Elements of Cognitive Dysfunction in Down Syndrome: Exploring the Role of APP
- (2011) Martha Millan Sanchez et al. BIOLOGICAL PSYCHIATRY
- APP and APLP2 are essential at PNS and CNS synapses for transmission, spatial learning and LTP
- (2011) Sascha W Weyer et al. EMBO JOURNAL
- A perfect storm: Converging paths of epilepsy and Alzheimer’s dementia intersect in the hippocampal formation
- (2011) Jeffrey Noebels EPILEPSIA
- The amyloid precursor protein and its homologues: Structural and functional aspects of native and pathogenic oligomerization
- (2011) Daniela Kaden et al. EUROPEAN JOURNAL OF CELL BIOLOGY
- Age-dependent Accumulation of Soluble Amyloid β (Aβ) Oligomers Reverses the Neuroprotective Effect of Soluble Amyloid Precursor Protein-α (sAPPα) by Modulating Phosphatidylinositol 3-Kinase (PI3K)/Akt-GSK-3β Pathway in Alzheimer Mouse Model
- (2011) Sebastian Jimenez et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Secreted Human Amyloid Precursor Protein Binds Semaphorin 3a and Prevents Semaphorin-Induced Growth Cone Collapse
- (2011) Margaret H. Magdesian et al. PLoS One
- The roles of amyloid precursor protein (APP) in neurogenesis
- (2011) Zhi-dong Zhou et al. Cell Adhesion & Migration
- Roles of amyloid precursor protein family members in neuroprotection, stress signaling and aging
- (2011) Donat Kögel et al. EXPERIMENTAL BRAIN RESEARCH
- TAG-1 is an inhibitor of TGFβ2-induced neuronal death via amyloid β precursor protein
- (2010) Nobuyuki Tachi et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Liposome-incorporated DHA increases neuronal survival by enhancing non-amyloidogenic APP processing
- (2010) Gunter P. Eckert et al. BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES
- Acute estradiol protects CA1 neurons from ischemia-induced apoptotic cell death via the PI3K/Akt pathway
- (2010) Teresa Jover-Mengual et al. BRAIN RESEARCH
- Molecular mechanisms of neurodegeneration in Alzheimer's disease
- (2010) L. Crews et al. HUMAN MOLECULAR GENETICS
- sAPPα antagonizes dendritic degeneration and neuron death triggered by proteasomal stress
- (2010) Ekaterini Copanaki et al. MOLECULAR AND CELLULAR NEUROSCIENCE
- Amyloid precursor protein and its homologues: a family of proteolysis-dependent receptors
- (2009) Kristin T. Jacobsen et al. CELLULAR AND MOLECULAR LIFE SCIENCES
- Heterotrimeric G Proteins and Apoptosis: Intersecting Signaling Pathways Leading to Context Dependent Phenotypes
- (2009) Vijay Yanamadala et al. CURRENT MOLECULAR MEDICINE
- Interactions between the amyloid precursor protein C-terminal domain and G proteins mediate calcium dysregulation and amyloid β toxicity in Alzheimer’s disease
- (2009) Gideon M. Shaked et al. FEBS Journal
- Neuroprotective Secreted Amyloid Precursor Protein Acts by Disrupting Amyloid Precursor Protein Dimers
- (2009) Matthias Gralle et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Interaction of Reelin with Amyloid Precursor Protein Promotes Neurite Outgrowth
- (2009) H.-S. Hoe et al. JOURNAL OF NEUROSCIENCE
- Presynaptic and Postsynaptic Interaction of the Amyloid Precursor Protein Promotes Peripheral and Central Synaptogenesis
- (2009) Z. Wang et al. JOURNAL OF NEUROSCIENCE
- Antibody binding to cell surface amyloid precursor protein induces neuronal injury by deregulating the phosphorylation of focal adhesion signaling related proteins
- (2009) Yu-Xia Xu et al. NEUROSCIENCE LETTERS
- Molecular Mechanisms of Go Signaling
- (2009) Meisheng Jiang et al. NEUROSIGNALS
- Interaction of amyloid precursor protein with contactins and NgCAM in the retinotectal system
- (2008) M. Osterfield et al. DEVELOPMENT
- Regulation of neurite outgrowth by Gi/o signaling pathways
- (2008) Kenneth et al. Frontiers in Bioscience-Landmark
- A TAG1-APP signalling pathway through Fe65 negatively modulates neurogenesis
- (2008) Quan-Hong Ma et al. NATURE CELL BIOLOGY
- Secreted APP regulates the function of full-length APP in neurite outgrowth through interaction with integrin beta1
- (2008) Tracy L Young-Pearse et al. Neural Development
- Amyloid-β precursor protein mediates neuronal toxicity of amyloid β through Go protein activation
- (2008) Francisco Sola Vigo et al. NEUROBIOLOGY OF AGING
- Heterotrimeric G protein activation by G-protein-coupled receptors
- (2007) William M. Oldham et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
Become a Peeref-certified reviewer
The Peeref Institute provides free reviewer training that teaches the core competencies of the academic peer review process.
Get StartedAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started