The Role of BiP Retrieval by the KDEL Receptor in the Early Secretory Pathway and its Effect on Protein Quality Control and Neurodegeneration

The genetic background of Parkinson's disease: current progress and future prospects

(2016) K. Kalinderi et al.   ACTA NEUROLOGICA SCANDINAVICA

Protein aggregation and ER stress

(2016) Navit Ogen-Shtern et al.   BRAIN RESEARCH

Sublethal endoplasmic reticulum stress caused by the mutation of immunoglobulin heavy chain-binding protein induces the synthesis of a mitochondrial protein, pyrroline-5-carboxylate reductase 1

(2016) Hisayo Jin et al.   CELL STRESS & CHAPERONES

Activation of HIPK2 Promotes ER Stress-Mediated Neurodegeneration in Amyotrophic Lateral Sclerosis

(2016) Sebum Lee et al.   NEURON

C9orf72 Hexanucleotide Expansions Are Associated with Altered Endoplasmic Reticulum Calcium Homeostasis and Stress Granule Formation in Induced Pluripotent Stem Cell-Derived Neurons from Patients with Amyotrophic Lateral Sclerosis and Frontotemporal Demen

(2016) Ruxandra Dafinca et al.   STEM CELLS

Reelin and Neuropsychiatric Disorders

(2016) Kazuhiro Ishii et al.   Frontiers in Cellular Neuroscience

Phenylbutyric Acid: Simple Structure - Multiple Effects

(2015) Magdalena Kusaczuk et al.   CURRENT PHARMACEUTICAL DESIGN

Huntingtin proteolysis releases non-polyQ fragments that cause toxicity through dynamin 1 dysregulation

(2015) M.-T. El-Daher et al.   EMBO JOURNAL

Tauroursodeoxycholic acid in the treatment of patients with amyotrophic lateral sclerosis

(2015) A. E. Elia et al.   EUROPEAN JOURNAL OF NEUROLOGY

BiP and Its Nucleotide Exchange Factors Grp170 and Sil1: Mechanisms of Action and Biological Functions

(2015) Julia Behnke et al.   JOURNAL OF MOLECULAR BIOLOGY

Sil1, a nucleotide exchange factor for BiP, is not required for antibody assembly or secretion

(2015) Viraj P. Ichhaporia et al.   MOLECULAR BIOLOGY OF THE CELL

Di-O-demethylcurcumin protects SK-N-SH cells against mitochondrial and endoplasmic reticulum-mediated apoptotic cell death induced by Aβ25-35

(2015) Decha Pinkaew et al.   NEUROCHEMISTRY INTERNATIONAL

How the Wnt signaling pathway protects from neurodegeneration: the mitochondrial scenario

(2015) Macarena S. Arrázola et al.   Frontiers in Cellular Neuroscience

KDEL receptor 1 regulates T-cell homeostasis via PP1 that is a key phosphatase for ISR

(2015) Daisuke Kamimura et al.   Nature Communications

Pathways Disrupted in Human ALS Motor Neurons Identified through Genetic Correction of Mutant SOD1

(2014) Evangelos Kiskinis et al.   Cell Stem Cell

Chemical corrector treatment ameliorates increased seizure susceptibility in a mouse model of familial epilepsy

(2014) Norihiko Yokoi et al.   NATURE MEDICINE

Late-Onset of Spinal Neurodegeneration in Knock-In Mice Expressing a Mutant BiP

(2014) Hisayo Jin et al.   PLoS One

The Unfolded Protein Response and Chemical Chaperones Reduce Protein Misfolding and Colitis in Mice

(2013) Stewart Siyan Cao et al.   GASTROENTEROLOGY

Depletion of Molecular Chaperones from the Endoplasmic Reticulum and Fragmentation of the Golgi Apparatus Associated with Pathogenesis in Pelizaeus-Merzbacher Disease

(2013) Yurika Numata et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Functional and morphological impact of ER stress on mitochondria

(2013) Kayleen Vannuvel et al.   JOURNAL OF CELLULAR PHYSIOLOGY

The KDEL receptor couples to Gαq/11to activate Src kinases and regulate transport through the Golgi

(2012) Monica Giannotta et al.   EMBO JOURNAL

The endoplasmic reticulum stress response in aging and age-related diseases

(2012) Marishka K. Brown et al.   Frontiers in Physiology

The unfolded protein response is associated with early tau pathology in the hippocampus of tauopathies

(2011) Diana AT Nijholt et al.   JOURNAL OF PATHOLOGY

Apolipoprotein E in Alzheimer's disease and other neurological disorders

(2011) Philip B Verghese et al.   LANCET NEUROLOGY

The Aβ oligomer hypothesis for synapse failure and memory loss in Alzheimer’s disease

(2011) Sergio T. Ferreira et al.   NEUROBIOLOGY OF LEARNING AND MEMORY

Expanded GGGGCC Hexanucleotide Repeat in Noncoding Region of C9ORF72 Causes Chromosome 9p-Linked FTD and ALS

(2011) Mariely DeJesus-Hernandez et al.   NEURON

A Hexanucleotide Repeat Expansion in C9ORF72 Is the Cause of Chromosome 9p21-Linked ALS-FTD

(2011) Alan E. Renton et al.   NEURON

The KDEL receptor induces autophagy to promote the clearance of neurodegenerative disease-related proteins

(2011) P. Wang et al.   NEUROSCIENCE

The Unfolded Protein Response: From Stress Pathway to Homeostatic Regulation

(2011) P. Walter et al.   SCIENCE

Amyloid β oligomers induce Ca2+ dysregulation and neuronal death through activation of ionotropic glutamate receptors

(2010) Elena Alberdi et al.   CELL CALCIUM

An intimate liaison: spatial organization of the endoplasmic reticulum–mitochondria relationship

(2010) Olga Martins de Brito et al.   EMBO JOURNAL

Amyloid-β Triggers the Release of Neuronal Hexokinase 1 from Mitochondria

(2010) Leonardo M. Saraiva et al.   PLoS One

ApoE4 reduces glutamate receptor function and synaptic plasticity by selectively impairing ApoE receptor recycling

(2010) Y. Chen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The evolving understanding of COPI vesicle formation

(2009) Victor W. Hsu et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Reelin Secreted by GABAergic Neurons Regulates Glutamate Receptor Homeostasis

(2009) Cecilia Gonzalez Campo et al.   PLoS One

Reelin signaling antagonizes  -amyloid at the synapse

(2009) M. S. Durakoglugil et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Dysfunction of the ER chaperone BiP accelerates the renal tubular injury

(2008) Keita Kimura et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

ALS-linked mutant SOD1 induces ER stress- and ASK1-dependent motor neuron death by targeting Derlin-1

(2008) H. Nishitoh et al.   GENES & DEVELOPMENT