Chemical corrector treatment ameliorates increased seizure susceptibility in a mouse model of familial epilepsy

Functional phylogenetic analysis of LGI proteins identifies an interaction motif crucial for myelination

(2014) L. Kegel et al.   DEVELOPMENT

Autoantibodies to Epilepsy-Related LGI1 in Limbic Encephalitis Neutralize LGI1-ADAM22 Interaction and Reduce Synaptic AMPA Receptors

(2013) T. Ohkawa et al.   JOURNAL OF NEUROSCIENCE

Clinical and Experimental Applications of Sodium Phenylbutyrate

(2013) Tommaso Iannitti et al.   Drugs in research & development

Proteostasis Modulators Prolong Missense VHL Protein Activity and Halt Tumor Progression

(2013) Chunzhang Yang et al.   Cell Reports

Fixing cystic fibrosis by correcting CFTR domain assembly

(2012) Tsukasa Okiyoneda et al.   JOURNAL OF CELL BIOLOGY

Domain-dependent clustering and genotype-phenotype analysis of LGI1 mutations in ADPEAF

(2012) Y.-Y. Ho et al.   NEUROLOGY

Reduction of ER stress via a chemical chaperone prevents disease phenotypes in a mouse model of primary open angle glaucoma

(2011) Gulab S. Zode et al.   JOURNAL OF CLINICAL INVESTIGATION

Familial temporal lobe epilepsy with psychic auras associated with a novel LGI1 mutation

(2011) P. Striano et al.   NEUROLOGY

Histone deacetylase inhibitors prevent the degradation and restore the activity of glucocerebrosidase in Gaucher disease

(2011) J. Lu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Electroclinical characterization of epileptic seizures in leucine-rich, glioma-inactivated 1-deficient mice

(2010) Elodie Chabrol et al.   BRAIN

Antibodies to Kv1 potassium channel-complex proteins leucine-rich, glioma inactivated 1 protein and contactin-associated protein-2 in limbic encephalitis, Morvan’s syndrome and acquired neuromyotonia

(2010) Sarosh R. Irani et al.   BRAIN

TARPs γ-2 and γ-7 are essential for AMPA receptor expression in the cerebellum

(2010) Maya Yamazaki et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Lgi1 null mutant mice exhibit myoclonic seizures and CA1 neuronal hyperexcitability

(2010) Y. Eugene Yu et al.   HUMAN MOLECULAR GENETICS

Adam22 Is a Major Neuronal Receptor for Lgi4-Mediated Schwann Cell Signaling

(2010) E. Ozkaynak et al.   JOURNAL OF NEUROSCIENCE

Investigation of LGI1 as the antigen in limbic encephalitis previously attributed to potassium channels: a case series

(2010) Meizan Lai et al.   LANCET NEUROLOGY

Disruption of LGI1–linked synaptic complex causes abnormal synaptic transmission and epilepsy

(2010) Yuko Fukata et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The rapidly expanding CREC protein family: members, localization, function, and role in disease

(2009) Bent Honoré   BIOESSAYS

LGI1mutations in autosomal dominant and sporadic lateral temporal epilepsy

(2009) Carlo Nobile et al.   HUMAN MUTATION

Mobile DHHC palmitoylating enzyme mediates activity-sensitive synaptic targeting of PSD-95

(2009) Jun Noritake et al.   JOURNAL OF CELL BIOLOGY

LGI1-associated epilepsy through altered ADAM23-dependent neuronal morphology

(2009) Katherine Owuor et al.   MOLECULAR AND CELLULAR NEUROSCIENCE

Reduced histone deacetylase 7 activity restores function to misfolded CFTR in cystic fibrosis

(2009) Darren M Hutt et al.   Nature Chemical Biology

Arrested maturation of excitatory synapses in autosomal dominant lateral temporal lobe epilepsy

(2009) Yu-Dong Zhou et al.   NATURE MEDICINE

Rescue of CF airway epithelial cell function in vitro by a CFTR potentiator, VX-770

(2009) F. Van Goor et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Chemical and Biological Approaches Synergize to Ameliorate Protein-Folding Diseases

(2008) Ting-Wei Mu et al.   CELL

Penetrance of LGI1 mutations in autosomal dominant partial epilepsy with auditory features

(2008) M. J. Rosanoff et al.   NEUROLOGY