Neurological Complications of HIV Infection

High Number of Activated CD8+ T Cells Targeting HIV Antigens Are Present in Cerebrospinal Fluid in Acute HIV Infection

(2017) Cari F. Kessing et al.   JAIDS-JOURNAL OF ACQUIRED IMMUNE DEFICIENCY SYNDROMES

HIV persistence in tissue macrophages of humanized myeloid-only mice during antiretroviral therapy

(2017) Jenna B Honeycutt et al.   NATURE MEDICINE

Maraviroc-intensified combined antiretroviral therapy improves cognition in virally suppressed HIV-associated neurocognitive disorder

(2016) Thomas M. Gates et al.   AIDS

Rates of non-confounded HIV-associated neurocognitive disorders in men initiating combination antiretroviral therapy during primary infection

(2016) Teresa H. Evering et al.   AIDS

Macrophages sustain HIV replication in vivo independently of T cells

(2016) Jenna B. Honeycutt et al.   JOURNAL OF CLINICAL INVESTIGATION

HIV DNA Is Frequently Present within Pathologic Tissues Evaluated at Autopsy from Combined Antiretroviral Therapy-Treated Patients with Undetectable Viral Loads

(2016) Susanna L. Lamers et al.   JOURNAL OF VIROLOGY

Plasma Concentration of the Neurofilament Light Protein (NFL) is a Biomarker of CNS Injury in HIV Infection: A Cross-Sectional Study

(2016) Magnus Gisslén et al.   EBioMedicine

APOE ε4 moderates abnormal CSF-abeta-42 levels, while neurocognitive impairment is associated with abnormal CSF tau levels in HIV+ individuals – a cross-sectional observational study

(2015) Lucette A Cysique et al.   BMC Neurology

The CCL2/CCR2 Axis in the Pathogenesis of HIV-1 Infection: A New Cellular Target for Therapy?

(2015) Daniela Angela Covino et al.   CURRENT DRUG TARGETS

Neuropsychological Impairment in Acute HIV and the Effect of Immediate Antiretroviral Therapy

(2015) Idil Kore et al.   JAIDS-JOURNAL OF ACQUIRED IMMUNE DEFICIENCY SYNDROMES

Blood brain barrier impairment is associated with cerebrospinal fluid markers of neuronal damage in HIV-positive patients

(2015) A. Calcagno et al.   JOURNAL OF NEUROVIROLOGY

Compartmentalized Replication of R5 T Cell-Tropic HIV-1 in the Central Nervous System Early in the Course of Infection

(2015) Christa Buckheit Sturdevant et al.   PLoS Pathogens

Blood-brain barrier dysfunction in disorders of the developing brain

(2015) Raffaella Moretti et al.   Frontiers in Neuroscience

Neurological Response to cART vs. cART plus Integrase Inhibitor and CCR5 Antagonist Initiated during Acute HIV

(2015) Victor G. Valcour et al.   PLoS One

Low levels of HIV-1 RNA detected in the cerebrospinal fluid after up to 10 years of suppressive therapy are associated with local immune activation

(2014) Viktor Dahl et al.   AIDS

Short Communication: Focal Encephalitis Related to Viral Escape and Resistance Emergence in Cerebrospinal Fluid in a Patient on Lopinavir/Ritonavir Monotherapy with Plasma HIV-1 RNA Suppression

(2014) Arkaitz Imaz et al.   AIDS RESEARCH AND HUMAN RETROVIRUSES

Comparison of Risk and Age at Diagnosis of Myocardial Infarction, End-Stage Renal Disease, and Non-AIDS-Defining Cancer in HIV-Infected Versus Uninfected Adults

(2014) Keri N. Althoff et al.   CLINICAL INFECTIOUS DISEASES

Asymptomatic HIV-associated neurocognitive impairment increases risk for symptomatic decline

(2014) I. Grant et al.   NEUROLOGY

CSF neurofilament light differs in neurodegenerative diseases and predicts severity and survival

(2014) T. Skillback et al.   NEUROLOGY

White Matter Signal Abnormalities in Children With Suspected HIV-related Neurologic Disease on Early Combination Antiretroviral Therapy

(2014) Christelle Ackermann et al.   PEDIATRIC INFECTIOUS DISEASE JOURNAL

Cerebrospinal Fluid (CSF) Neuronal Biomarkers across the Spectrum of HIV Infection: Hierarchy of Injury and Detection

(2014) Julia Peterson et al.   PLoS One

Central Nervous System HIV Infection in “Less-Drug Regimen” Antiretroviral Therapy Simplification Strategies

(2014) Nicola Gianotti et al.   SEMINARS IN NEUROLOGY

Update on the key developments of the neurologic complications in children infected with HIV

(2014) Jo M. Wilmshurst et al.   Current Opinion in HIV and AIDS

Anti-α4 Antibody Treatment Blocks Virus Traffic to the Brain and Gut Early, and Stabilizes CNS Injury Late in Infection

(2014) Jennifer H. Campbell et al.   PLoS Pathogens

Adverse events associated with nevirapine and efavirenz-based first-line antiretroviral therapy

(2013) Zara Shubber et al.   AIDS

Randomized Trial of Central Nervous System–Targeted Antiretrovirals for HIV-Associated Neurocognitive Disorder

(2013) Ronald J. Ellis et al.   CLINICAL INFECTIOUS DISEASES

Neurological and psychiatric tolerability of rilpivirine (TMC278)vs.efavirenz in treatment-naïve, HIV-1-infected patients at 48 weeks

(2013) AM Mills et al.   HIV MEDICINE

Cerebrospinal fluid neopterin decay characteristics after initiation of antiretroviral therapy

(2013) Aylin Yilmaz et al.   Journal of Neuroinflammation

Cellular Composition of Cerebrospinal Fluid in HIV-1 Infected and Uninfected Subjects

(2013) Emily L. Ho et al.   PLoS One

Discontinuation of efavirenz therapy in HIV patients due to neuropsychiatric adverse effects

(2013) Peter Derek Christian Leutscher et al.   SCANDINAVIAN JOURNAL OF INFECTIOUS DISEASES

Cerebrospinal fluid HIV escape associated with progressive neurologic dysfunction in patients on antiretroviral therapy with well controlled plasma viral load

(2012) Michael J. Peluso et al.   AIDS

Improved Neuropsychological and Neurological Functioning Across Three Antiretroviral Regimens in Diverse Resource-Limited Settings: AIDS Clinical Trials Group Study A5199, the International Neurological Study

(2012) K. Robertson et al.   CLINICAL INFECTIOUS DISEASES

Central Nervous System Viral Invasion and Inflammation During Acute HIV Infection

(2012) Victor Valcour et al.   JOURNAL OF INFECTIOUS DISEASES

A diffusion tensor imaging and neurocognitive study of HIV-positive children who are HAART-naïve “slow progressors”

(2012) Jacqueline Hoare et al.   JOURNAL OF NEUROVIROLOGY

Impact of HIV Severity on Cognitive and Adaptive Functioning During Childhood and Adolescence

(2012) Renee Smith et al.   PEDIATRIC INFECTIOUS DISEASE JOURNAL

Change in Brain Magnetic Resonance Spectroscopy after Treatment during Acute HIV Infection

(2012) Napapon Sailasuta et al.   PLoS One

Persistence of HIV-associated cognitive impairment, inflammation, and neuronal injury in era of highly active antiretroviral treatment

(2011) Jarek Harezlak et al.   AIDS

Premature Age-Related Comorbidities Among HIV-Infected Persons Compared With the General Population

(2011) G. Guaraldi et al.   CLINICAL INFECTIOUS DISEASES

HIV-1 infection and cognitive impairment in the cART era: a review

(2010) Judith Schouten et al.   AIDS

Incidence and Impact on Mortality of Severe Neurocognitive Disorders in Persons With and Without HIV Infection: A Danish Nationwide Cohort Study

(2010) F.-X. Lescure et al.   CLINICAL INFECTIOUS DISEASES

HIV‐1 Viral Escape in Cerebrospinal Fluid of Subjects on Suppressive Antiretroviral Treatment

(2010) Arvid Edén et al.   JOURNAL OF INFECTIOUS DISEASES

HIV-associated neurocognitive disorders before and during the era of combination antiretroviral therapy: differences in rates, nature, and predictors

(2010) Robert K. Heaton et al.   JOURNAL OF NEUROVIROLOGY

Impact of combination antiretroviral therapy on cerebrospinal fluid HIV RNA and neurocognitive performance

(2009) Christina M Marra et al.   AIDS

The impact of AIDS diagnoses on long-term neurocognitive and psychiatric outcomes of surviving adolescents with perinatally acquired HIV

(2009) Sarah M Wood et al.   AIDS