miR-206 inhibits the growth of hepatocellular carcinoma cells via targeting CDK9

miR-206 functions as a novel cell cycle regulator and tumor suppressor in clear-cell renal cell carcinoma

(2016) Haibing Xiao et al.   CANCER LETTERS

Mechanism of Regulatory Effect of MicroRNA-206 on Connexin 43 in Distant Metastasis of Breast Cancer

(2016) Jia Ming et al.   CHINESE MEDICAL JOURNAL

Targeting CDK9: a promising therapeutic opportunity in prostate cancer

(2016) Muhammed H Rahaman et al.   ENDOCRINE-RELATED CANCER

Increased Serum miR-206 Level Predicts Conversion from Amnestic Mild Cognitive Impairment to Alzheimer’s Disease: A 5-Year Follow-up Study

(2016) Bing Xie et al.   JOURNAL OF ALZHEIMERS DISEASE

Cyclin Dependent Kinase 9 Inhibitors for Cancer Therapy

(2016) Yogesh A. Sonawane et al.   JOURNAL OF MEDICINAL CHEMISTRY

MicroRNA-206 Inhibited the Progression of Glioblastoma Through BCL-2

(2016) Wenjiong Hao et al.   JOURNAL OF MOLECULAR NEUROSCIENCE

PAX7 is a required target for microRNA-206-induced differentiation of fusion-negative rhabdomyosarcoma

(2016) J A Hanna et al.   Cell Death & Disease

CDK9 inhibitors selectively target estrogen receptor-positive breast cancer cells through combined inhibition of MYB and MCL-1 expression

(2016) Partha Mitra et al.   Oncotarget

LncRNA-RMRP promotes carcinogenesis by acting as a miR-206 sponge and is used as a novel biomarker for gastric cancer

(2016) Yongfu Shao et al.   Oncotarget

Early diagnosis of Alzheimer’s disease from elevated olfactory mucosal miR-206 level

(2016) Jangsup Moon et al.   Scientific Reports

The impact of CDK9 on radiosensitivity, DNA damage repair and cell cycling of HNSCC cancer cells

(2015) KATJA STORCH et al.   INTERNATIONAL JOURNAL OF ONCOLOGY

miR-154 targeting ZEB2 in hepatocellular carcinoma functions as a potential tumor suppressor

(2015) Xiaoli Pang et al.   ONCOLOGY REPORTS

microRNA-206 attenuates tumor proliferation and migration involving the downregulation of NOTCH3 in colorectal cancer

(2015) XIAO-WEI WANG et al.   ONCOLOGY REPORTS

Up-regulation of CDK9 kinase activity and Mcl-1 stability contributes to the acquired resistance to cyclin-dependent kinase inhibitors in leukemia

(2015) Yuh-Ying Yeh et al.   Oncotarget

Hepatocellular carcinoma epidemiology

(2014) Cristina Bosetti et al.   BEST PRACTICE & RESEARCH IN CLINICAL GASTROENTEROLOGY

MicroRNA-874 inhibits cell proliferation and induces apoptosis in human breast cancer by targeting CDK9

(2014) Ling Wang et al.   FEBS LETTERS

CDK9-mediated transcription elongation is required for MYC addiction in hepatocellular carcinoma

(2014) Chun-Hao Huang et al.   GENES & DEVELOPMENT

Hepatocellular carcinoma: clinical frontiers and perspectives

(2014) Jordi Bruix et al.   GUT

MicroRNA-206 overexpression promotes apoptosis, induces cell cycle arrest and inhibits the migration of human hepatocellular carcinoma HepG2 cells

(2014) WEIWEI LIU et al.   INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE

A Novel CDK9 Inhibitor Shows Potent Antitumor Efficacy in Preclinical Hematologic Tumor Models

(2014) T. Yin et al.   MOLECULAR CANCER THERAPEUTICS

Trans-ancestry mutational landscape of hepatocellular carcinoma genomes

(2014) Yasushi Totoki et al.   NATURE GENETICS

MiR-206 decreases brain-derived neurotrophic factor levels in a transgenic mouse model of Alzheimer’s disease

(2014) Ning Tian et al.   Neuroscience Bulletin

Regulation of CDK9 Activity by Phosphorylation and Dephosphorylation

(2014) Sergei Nekhai et al.   Biomed Research International

MiR-206 inhibits gastric cancer proliferation in part by repressing CyclinD2

(2013) Lin Zhang et al.   CANCER LETTERS

Decreased expression of microRNA-206 in breast cancer and its association with disease characteristics and patient survival

(2013) Yuyang Li et al.   JOURNAL OF INTERNATIONAL MEDICAL RESEARCH

MicroRNA-206 is involved in hypoxia-induced pulmonary hypertension through targeting of the HIF-1α/Fhl-1 pathway

(2013) Junqiu Yue et al.   LABORATORY INVESTIGATION

Emerging landscape of oncogenic signatures across human cancers

(2013) Giovanni Ciriello et al.   NATURE GENETICS

MicroRNA-206 induces G1 arrest in melanoma by inhibition of CDK4 and Cyclin D

(2013) Robert W. Georgantas et al.   Pigment Cell & Melanoma Research

Expression of the tumor suppressor miR-206 is associated with cellular proliferative inhibition and impairs invasion in ERα-positive endometrioid adenocarcinoma

(2011) Xiaoyue Chen et al.   CANCER LETTERS

Ibulocydine Is a Novel Prodrug Cdk Inhibitor That Effectively Induces Apoptosis in Hepatocellular Carcinoma Cells

(2011) Seung-Ju Cho et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Cyclin-dependent kinase inhibitor, P276-00 induces apoptosis in multiple myeloma cells by inhibition of Cdk9-T1 and RNA polymerase II-dependent transcription

(2011) Sonal M. Manohar et al.   LEUKEMIA RESEARCH

Hepatocellular Carcinoma

(2011) Hashem B. El-Serag   NEW ENGLAND JOURNAL OF MEDICINE

HMGB1 Attenuates Cardiac Remodelling in the Failing Heart via Enhanced Cardiac Regeneration and miR-206-Mediated Inhibition of TIMP-3

(2011) Federica Limana et al.   PLoS One

Wogonin and related natural flavones are inhibitors of CDK9 that induce apoptosis in cancer cells by transcriptional suppression of Mcl-1

(2011) G Polier et al.   Cell Death & Disease

MicroRNA-206 expression levels correlate with clinical behaviour of rhabdomyosarcomas

(2010) E Missiaglia et al.   BRITISH JOURNAL OF CANCER

Role of the cyclin-dependent kinase 9-related pathway in mammalian gene expression and human diseases

(2010) Gaetano Romano et al.   CELL CYCLE

Cyclin T1 overexpression induces malignant transformation and tumor growth

(2010) Cristian Moiola et al.   CELL CYCLE

MicroRNAs 1, 133, and 206: Critical factors of skeletal and cardiac muscle development, function, and disease

(2009) W.H. Davin Townley-Tilson et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

MicroRNA-1/206 Targets c-Metand Inhibits Rhabdomyosarcoma Development

(2009) Dongsheng Yan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Hepatocellular carcinoma: current trends in worldwide epidemiology, risk factors, diagnosis and therapeutics

(2009) Mohamed IF Shariff et al.   Expert Review of Gastroenterology & Hepatology