Targeting resolution of neuroinflammation after ischemic stroke with a lipoxin A4 analog: Protective mechanisms and long-term effects on neurological recovery

Modulation of the inflammatory response to chitosan through M2 macrophage polarization using pro-resolution mediators

(2015) Daniela P. Vasconcelos et al.   BIOMATERIALS

Immune phenotypes of microglia in human neurodegenerative disease: challenges to detecting microglial polarization in human brains

(2015) Douglas G. Walker et al.   Alzheimers Research & Therapy

Rational modulation of the innate immune system for neuroprotection in ischemic stroke

(2015) Diana Amantea et al.   Frontiers in Neuroscience

The Ischemic Environment Drives Microglia and Macrophage Function

(2015) Stefano Fumagalli et al.   Frontiers in Neurology

Detrimental role of the EP1 prostanoid receptor in blood-brain barrier damage following experimental ischemic stroke

(2015) Jan C. Frankowski et al.   Scientific Reports

Long-term functional recovery and compensation after cerebral ischemia in rats

(2014) Sylvie Girard et al.   BEHAVIOURAL BRAIN RESEARCH

L-Kynurenine/Aryl Hydrocarbon Receptor Pathway Mediates Brain Damage After Experimental Stroke

(2014) María I. Cuartero et al.   CIRCULATION

Protective Effects of BML-111 on Cerulein-Induced Acute Pancreatitis-Associated Lung Injury via Activation of Nrf2/ARE Signaling Pathway

(2014) Ying-zhen Wang et al.   INFLAMMATION

Door-to-Needle Times for Tissue Plasminogen Activator Administration and Clinical Outcomes in Acute Ischemic Stroke Before and After a Quality Improvement Initiative

(2014) Gregg C. Fonarow et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Microglial and macrophage polarization—new prospects for brain repair

(2014) Xiaoming Hu et al.   Nature Reviews Neurology

Inflammatory cell recruitment after experimental thromboembolic stroke in rats

(2014) J. Lehmann et al.   NEUROSCIENCE

Stereological and Flow Cytometry Characterization of Leukocyte Subpopulations in Models of Transient or Permanent Cerebral Ischemia

(2014) Iván Ballesteros et al.   Jove-Journal of Visualized Experiments

Microglia/Macrophage Polarization Dynamics in White Matter after Traumatic Brain Injury

(2013) Guohua Wang et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Neurovascular protection by post-ischemic intravenous injections of the lipoxin A4receptor agonist, BML-111, in a rat model of ischemic stroke

(2013) Kimberly E. Hawkins et al.   JOURNAL OF NEUROCHEMISTRY

Tissue-resident macrophages

(2013) Luke C Davies et al.   NATURE IMMUNOLOGY

Lipoxin A4 ameliorates cerebral ischaemia/reperfusion injury through upregulation of nuclear factor erythroid 2-related factor 2

(2013) Le Wu et al.   NEUROLOGICAL RESEARCH

BML-111, a Lipoxin Receptor Agonist, Attenuates Ventilator-Induced Lung Injury in Rats

(2013) Hongbin Li et al.   SHOCK

Lipoxin A4 Inhibits 5-Lipoxygenase Translocation and Leukotrienes Biosynthesis to Exert a Neuroprotective Effect in Cerebral Ischemia/Reperfusion Injury

(2012) Le Wu et al.   JOURNAL OF MOLECULAR NEUROSCIENCE

The smallest stroke: occlusion of one penetrating vessel leads to infarction and a cognitive deficit

(2012) Andy Y Shih et al.   NATURE NEUROSCIENCE

BML-111, a lipoxin receptor agonist, protects haemorrhagic shock-induced acute lung injury in rats

(2012) Jie Gong et al.   RESUSCITATION

Microglia/Macrophage Polarization Dynamics Reveal Novel Mechanism of Injury Expansion After Focal Cerebral Ischemia

(2012) Xiaoming Hu et al.   STROKE

A Lipoxin A4 Analog Ameliorates Blood–Brain Barrier Dysfunction and Reduces MMP-9 Expression in a Rat Model of Focal Cerebral Ischemia–Reperfusion Injury

(2011) Yan Wu et al.   JOURNAL OF MOLECULAR NEUROSCIENCE

The immunology of stroke: from mechanisms to translation

(2011) Costantino Iadecola et al.   NATURE MEDICINE

Isolation of Brain-infiltrating Leukocytes

(2011) Reghann G. LaFrance-Corey et al.   Jove-Journal of Visualized Experiments

Lipoxin A 4 analogue protects brain and reduces inflammation in a rat model of focal cerebral ischemia reperfusion

(2010) Xi-Hong Ye et al.   BRAIN RESEARCH

Lipoxin A4 attenuates zymosan-induced arthritis by modulating endothelin-1 and its effects

(2010) FP Conte et al.   BRITISH JOURNAL OF PHARMACOLOGY

Lipoxin A4 impairment of apoptotic signaling in macrophages: implication of the PI3K/Akt and the ERK/Nrf-2 defense pathways

(2010) P Prieto et al.   CELL DEATH AND DIFFERENTIATION

Neuroprotective Effect of Lipoxin A4 Methyl Ester in a Rat Model of Permanent Focal Cerebral Ischemia

(2010) Yan Wu et al.   JOURNAL OF MOLECULAR NEUROSCIENCE

Microglial activation in stroke: Therapeutic targets

(2010) Midori A. Yenari et al.   Neurotherapeutics

Inflammatory mechanisms in ischemic stroke: therapeutic approaches

(2009) Shaheen E Lakhan et al.   Journal of Translational Medicine

The Multifaceted Profile of Activated Microglia

(2009) Marina A. Lynch   MOLECULAR NEUROBIOLOGY

The adhesive removal test: a sensitive method to assess sensorimotor deficits in mice

(2009) Valentine Bouet et al.   Nature Protocols

Number Needed to Treat to Benefit and to Harm for Intravenous Tissue Plasminogen Activator Therapy in the 3- to 4.5-Hour Window

(2009) Jeffrey L. Saver et al.   STROKE

Temporal and Spatial Dynamics of Cerebral Immune Cell Accumulation in Stroke

(2009) Mathias Gelderblom et al.   STROKE

Update of the Stroke Therapy Academic Industry Roundtable Preclinical Recommendations

(2009) Marc Fisher et al.   STROKE

Formyl-peptide receptor like 1: A potent mediator of the Ca2+ release-activated Ca2+ current ICRAC

(2008) Yong-Sheng Li et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

BML-111, a lipoxin receptor agonist, modulates the immune response and reduces the severity of collagen-induced arthritis

(2008) L. Zhang et al.   INFLAMMATION RESEARCH

Thrombolysis with Alteplase 3 to 4.5 Hours after Acute Ischemic Stroke

(2008) Werner Hacke et al.   NEW ENGLAND JOURNAL OF MEDICINE