Reduced Osteoarthritis Severity in Aged Mice With Deletion of Macrophage Migration Inhibitory Factor

Macrophage migration inhibitory factor is essential for osteoclastogenic mechanisms in vitro and in vivo mouse model of arthritis

(2015) Ran Gu et al.   CYTOKINE

Cross-sectional and Longitudinal Associations between Knee Joint Effusion Synovitis and Knee Pain in Older Adults

(2015) Xia Wang et al.   JOURNAL OF RHEUMATOLOGY

Aging-related inflammation in osteoarthritis

(2015) M.A. Greene et al.   OSTEOARTHRITIS AND CARTILAGE

Alarmins S100A8/S100A9 aggravate osteophyte formation in experimental osteoarthritis and predict osteophyte progression in early human symptomatic osteoarthritis

(2014) R F P Schelbergen et al.   ANNALS OF THE RHEUMATIC DISEASES

The global burden of hip and knee osteoarthritis: estimates from the Global Burden of Disease 2010 study

(2014) Marita Cross et al.   ANNALS OF THE RHEUMATIC DISEASES

Targeting distinct tautomerase sites of D-DT and MIF with a single molecule for inhibition of neutrophil lung recruitment

(2014) Deepa Rajasekaran et al.   FASEB JOURNAL

Joint bleeding in factor VIII deficient mice causes an acute loss of trabecular bone and calcification of joint soft tissues which is prevented with aggressive factor replacement

(2014) A. G. Lau et al.   HAEMOPHILIA

Treatment efficacy of adipose-derived stem cells in experimental osteoarthritis is driven by high synovial activation and reflected by S100A8/A9 serum levels

(2014) R.F. Schelbergen et al.   OSTEOARTHRITIS AND CARTILAGE

Macrophage Migration Inhibitory Factor Down-Regulates the RANKL-RANK Signaling Pathway by Activating Lyn Tyrosine Kinase in Mouse Models

(2014) Se Hwan Mun et al.   Arthritis & Rheumatology

Depletion of Protease-Activated Receptor 2 but Not Protease-Activated Receptor 1 May Confer Protection Against Osteoarthritis in Mice Through Extracartilaginous Mechanisms

(2014) Miriam T. Jackson et al.   Arthritis & Rheumatology

Aging and Oxidative Stress Reduce the Response of Human Articular Chondrocytes to Insulin-like Growth Factor 1 and Osteogenic Protein 1

(2014) Richard F. Loeser et al.   Arthritis & Rheumatology

Association of MIF in serum and synovial fluid with severity of knee osteoarthritis

(2012) Minghui Liu et al.   CLINICAL BIOCHEMISTRY

MIF, MIF Alleles, and Prospects for Therapeutic Intervention in Autoimmunity

(2012) Richard Bucala   JOURNAL OF CLINICAL IMMUNOLOGY

What constitutes an “animal model of osteoarthritis” – the need for consensus?

(2012) C.B. Little et al.   OSTEOARTHRITIS AND CARTILAGE

CCR2 chemokine receptor signaling mediates pain in experimental osteoarthritis

(2012) R. E. Miller et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Interleukin-6 plays an essential role in hypoxia-inducible factor 2α-induced experimental osteoarthritic cartilage destruction in mice

(2011) Je-Hwang Ryu et al.   ARTHRITIS AND RHEUMATISM

Microarray analysis reveals age-related differences in gene expression during the development of osteoarthritis in mice

(2011) Richard F. Loeser et al.   ARTHRITIS AND RHEUMATISM

A Comprehensive Histological Assessment of Osteoarthritis Lesions in Mice

(2011) Margaret A. McNulty et al.   Cartilage

Age-Related Changes in the Musculoskeletal System and the Development of Osteoarthritis

(2010) Richard F. Loeser   CLINICS IN GERIATRIC MEDICINE

Macrophage migration inhibitory factor-knockout mice are long lived and respond to caloric restriction

(2010) James M. Harper et al.   FASEB JOURNAL

A Small-Molecule Macrophage Migration Inhibitory Factor Antagonist Protects against Glomerulonephritis in Lupus-Prone NZB/NZW F1 and MRL/lpr Mice

(2010) L. Leng et al.   JOURNAL OF IMMUNOLOGY

Macrophage migration inhibitory factor inhibits osteoclastogenesis

(2009) Claire Jacquin et al.   BONE

Oxidative Stress Inhibits Insulin-like Growth Factor-I Induction of Chondrocyte Proteoglycan Synthesis through Differential Regulation of Phosphatidylinositol 3-Kinase-Akt and MEK-ERK MAPK Signaling Pathways

(2009) Weihong Yin et al.   JOURNAL OF BIOLOGICAL CHEMISTRY