Review: Found in Translation: International Initiatives Pursuing Interleukin-1 Blockade for Treatment of Acute Kawasaki Disease

Role of Interleukin-1 Signaling in a Mouse Model of Kawasaki Disease–Associated Abdominal Aortic AneurysmSignificance

(2016) Daiko Wakita et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Rationale and study design for a phase I/IIa trial of anakinra in children with Kawasaki disease and early coronary artery abnormalities (the ANAKID trial)

(2016) Adriana H. Tremoulet et al.   Contemporary Clinical Trials

The Spectrum of Cardiovascular Lesions Requiring Intervention in Adults After Kawasaki Disease

(2016) John B. Gordon et al.   JACC-Cardiovascular Interventions

Pharmacokinetics and Pharmacodynamics of Canakinumab in Patients With Systemic Juvenile Idiopathic Arthritis

(2016) Haiying Sun et al.   JOURNAL OF CLINICAL PHARMACOLOGY

Variations in ORAI1 Gene Associated with Kawasaki Disease

(2016) Yoshihiro Onouchi et al.   PLoS One

Recommendations for the management of autoinflammatory diseases

(2015) Nienke M ter Haar et al.   ANNALS OF THE RHEUMATIC DISEASES

IL-1 Signaling Is Critically Required in Stromal Cells in Kawasaki Disease Vasculitis Mouse ModelSignificance

(2015) Youngho Lee et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Fine specificities of natural regulatory T cells after IVIG therapy in patients with Kawasaki disease

(2015) Jane C. Burns et al.   AUTOIMMUNITY

The immunomodulatory effects of intravenous immunoglobulin therapy in Kawasaki disease

(2015) Jane C Burns et al.   Expert Review of Clinical Immunology

Interleukin-1 function and role in rheumatic disease

(2015) Georg Schett et al.   Nature Reviews Rheumatology

2013 Update of the 2011 American College of Rheumatology Recommendations for the Treatment of Juvenile Idiopathic Arthritis: Recommendations for the Medical Therapy of Children With Systemic Juvenile Idiopathic Arthritis and Tuberculosis Screening Among C

(2015) Sarah Ringold et al.   ARTHRITIS AND RHEUMATISM

Specificity of regulatory T cells that modulate vascular inflammation

(2014) Alessandra Franco et al.   AUTOIMMUNITY

NLRP3 inflammasome activation and interleukin-1β release in macrophages require calcium but are independent of calcium-activated NADPH oxidases

(2014) Balázs Rada et al.   INFLAMMATION RESEARCH

Infliximab for intensification of primary therapy for Kawasaki disease: a phase 3 randomised, double-blind, placebo-controlled trial

(2014) Adriana H Tremoulet et al.   LANCET

MABp1, a first-in-class true human antibody targeting interleukin-1α in refractory cancers: an open-label, phase 1 dose-escalation and expansion study

(2014) David S Hong et al.   LANCET ONCOLOGY

High dose anakinra for treatment of severe neonatal Kawasaki disease: a case report

(2014) Ashley Shafferman et al.   Pediatric Rheumatology

Single-Nucleotide Polymorphism rs7251246 in ITPKC Is Associated with Susceptibility and Coronary Artery Lesions in Kawasaki Disease

(2014) Ho-Chang Kuo et al.   PLoS One

Calcium signaling and mitochondrial destabilization in the triggering of the NLRP3 inflammasome

(2014) Tiffany Horng   TRENDS IN IMMUNOLOGY

Global gene expression profiling identifies new therapeutic targets in acute Kawasaki disease

(2014) Long Truong Hoang et al.   Genome Medicine

Anakinra for cryopyrin-associated periodic syndrome

(2013) Isabelle Koné-Paut et al.   Expert Review of Clinical Immunology

Coronary artery outcomes among children with Kawasaki disease in the United States and Japan

(2013) Shohei Ogata et al.   INTERNATIONAL JOURNAL OF CARDIOLOGY

IL-1 enhances expansion, effector function, tissue localization, and memory response of antigen-specific CD8 T cells

(2013) Shlomo Z. Ben-Sasson et al.   JOURNAL OF EXPERIMENTAL MEDICINE

A child with severe relapsing Kawasaki disease rescued by IL-1 receptor blockade and extracorporeal membrane oxygenation

(2012) Sophie Cohen et al.   ANNALS OF THE RHEUMATIC DISEASES

Sustained response and prevention of damage progression in patients with neonatal-onset multisystem inflammatory disease treated with anakinra: A cohort study to determine three- and five-year outcomes

(2012) Cailin H. Sibley et al.   ARTHRITIS AND RHEUMATISM

Interleukin-1β Is Crucial for the Induction of Coronary Artery Inflammation in a Mouse Model of Kawasaki Disease

(2012) Youngho Lee et al.   CIRCULATION

Genetics of Kawasaki Disease

(2012) Yoshihiro Onouchi   CIRCULATION JOURNAL

The role of TGF-β and myofibroblasts in the arteritis of Kawasaki disease

(2012) Chisato Shimizu et al.   HUMAN PATHOLOGY

Efficacy of immunoglobulin plus prednisolone for prevention of coronary artery abnormalities in severe Kawasaki disease (RAISE study): a randomised, open-label, blinded-endpoints trial

(2012) Tohru Kobayashi et al.   LANCET

A functional polymorphism, rs28493229, in ITPKC and risk of Kawasaki disease: an integrated meta-analysis

(2012) Jiao Lou et al.   MOLECULAR BIOLOGY REPORTS

The calcium-sensing receptor regulates the NLRP3 inflammasome through Ca2+ and cAMP

(2012) Geun-Shik Lee et al.   NATURE

Treating inflammation by blocking interleukin-1 in a broad spectrum of diseases

(2012) Charles A. Dinarello et al.   NATURE REVIEWS DRUG DISCOVERY

Two Randomized Trials of Canakinumab in Systemic Juvenile Idiopathic Arthritis

(2012) Nicolino Ruperto et al.   NEW ENGLAND JOURNAL OF MEDICINE

Three Linked Vasculopathic Processes Characterize Kawasaki Disease: A Light and Transmission Electron Microscopic Study

(2012) Jan Marc Orenstein et al.   PLoS One

Critical role for calcium mobilization in activation of the NLRP3 inflammasome

(2012) T. Murakami et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Two-year results from an open-label, multicentre, phase III study evaluating the safety and efficacy of canakinumab in patients with cryopyrin-associated periodic syndrome across different severity phenotypes

(2011) J. B. Kuemmerle-Deschner et al.   ANNALS OF THE RHEUMATIC DISEASES

Genetic inactivation of IL-1 signaling enhances atherosclerotic plaque instability and reduces outward vessel remodeling in advanced atherosclerosis in mice

(2011) Matthew R. Alexander et al.   JOURNAL OF CLINICAL INVESTIGATION

IL-1  and IL-1  Recruit Different Myeloid Cells and Promote Different Stages of Sterile Inflammation

(2011) P. Rider et al.   JOURNAL OF IMMUNOLOGY

Genome-wide association study identifies FCGR2A as a susceptibility locus for Kawasaki disease

(2011) Chiea Chuen Khor et al.   NATURE GENETICS

Sterile inflammation of endothelial cell-derived apoptotic bodies is mediated by interleukin-1 

(2011) Y. Berda-Haddad et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Kawasaki Disease: Novel Insights into Etiology and Genetic Susceptibility

(2010) Anne H. Rowley   Annual Review of Medicine

Efficacy and safety of anakinra therapy in pediatric and adult patients with the autoinflammatory Muckle-Wells syndrome

(2010) Jasmin B. Kuemmerle-Deschner et al.   ARTHRITIS AND RHEUMATISM

Transforming Growth Factor-β Signaling Pathway in Patients With Kawasaki Disease

(2010) Chisato Shimizu et al.   Circulation-Cardiovascular Genetics

Transcript abundance patterns in Kawasaki disease patients with intravenous immunoglobulin resistance

(2010) Wen Fury et al.   HUMAN IMMUNOLOGY

Matrix metalloproteinase haplotypes associated with coronary artery aneurysm formation in patients with Kawasaki disease

(2010) Chisato Shimizu et al.   JOURNAL OF HUMAN GENETICS

Infliximab for Intravenous Immunoglobulin Resistance in Kawasaki Disease: A Retrospective Study

(2010) Mary Beth Son et al.   JOURNAL OF PEDIATRICS

Evaluation of Kawasaki Disease Risk-Scoring Systems for Intravenous Immunoglobulin Resistance

(2010) Lynn A. Sleeper et al.   JOURNAL OF PEDIATRICS

Association of CCR2-CCR5 Haplotypes and CCL3L1 Copy Number with Kawasaki Disease, Coronary Artery Lesions, and IVIG Responses in Japanese Children

(2010) Manju Mamtani et al.   PLoS One

Therapy of autoinflammatory syndromes

(2009) Hal M. Hoffman   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Involvement of Innate and Adaptive Immunity in a Murine Model of Coronary Arteritis Mimicking Kawasaki Disease

(2009) D. J. Schulte et al.   JOURNAL OF IMMUNOLOGY

Use of Canakinumab in the Cryopyrin-Associated Periodic Syndrome

(2009) Helen J. Lachmann et al.   NEW ENGLAND JOURNAL OF MEDICINE

Association of the matrix metalloproteinase-3 (−439C/G) promoter polymorphism with Kawasaki disease in Korean children

(2008) Young Mi Hong et al.   HEART AND VESSELS

Infliximab Treatment of Intravenous Immunoglobulin–Resistant Kawasaki Disease

(2008) Jane C. Burns et al.   JOURNAL OF PEDIATRICS

Resistance to Intravenous Immunoglobulin in Children with Kawasaki Disease

(2008) Adriana H. Tremoulet et al.   JOURNAL OF PEDIATRICS