IL-1β and TNFα inhibit GPR120 (FFAR4) and stimulate GPR84 (EX33) and GPR41 (FFAR3) fatty acid receptor expression in human adipocytes: implications for the anti-inflammatory action of n-3 fatty acids

Docosahexaenoic Acid

(2016) Philip C. Calder   ANNALS OF NUTRITION AND METABOLISM

Free-fatty acid receptor-4 (GPR120): Cellular and molecular function and its role in metabolic disorders

(2016) Nader H. Moniri   BIOCHEMICAL PHARMACOLOGY

Treatment with TUG891, a free fatty acid receptor 4 agonist, restores adipose tissue metabolic dysfunction following chronic sleep fragmentation in mice

(2016) D Gozal et al.   INTERNATIONAL JOURNAL OF OBESITY

GPR120 promotes adipogenesis through intracellular calcium and extracellular signal-regulated kinase 1/2 signal pathway

(2016) Tongxing Song et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

IL-1β(interleukin-1β) stimulates the production and release of multiple cytokines and chemokines by human preadipocytes

(2016) Suliman Y. Alomar et al.   ARCHIVES OF PHYSIOLOGY AND BIOCHEMISTRY

PCR arrays indicate that the expression of extracellular matrix and cell adhesion genes in human adipocytes is regulated by IL-1β (interleukin-1β)

(2016) Malgorzata A. Kępczyńska et al.   ARCHIVES OF PHYSIOLOGY AND BIOCHEMISTRY

Dietary Fatty Acids and Their Potential for Controlling Metabolic Diseases Through Activation of FFA4/GPR120

(2015) Trond Ulven et al.   Annual Review of Nutrition

Activity of dietary fatty acids on FFA1 and FFA4 and characterisation of pinolenic acid as a dual FFA1/FFA4 agonist with potential effect against metabolic diseases

(2015) Elisabeth Christiansen et al.   BRITISH JOURNAL OF NUTRITION

Characterizing pharmacological ligands to study the long-chain fatty acid receptors GPR40/FFA1 and GPR120/FFA4

(2015) G Milligan et al.   BRITISH JOURNAL OF PHARMACOLOGY

Eicosapentaenoic acid upregulates VEGF-A through both GPR120 and PPARγ mediated pathways in 3T3-L1 adipocytes

(2015) Arif U. Hasan et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

PCR array and protein array studies demonstrate that IL-1β(interleukin-1β) stimulates the expression and secretion of multiple cytokines and chemokines in human adipocytes

(2015) Suliman Y. Alomar et al.   ARCHIVES OF PHYSIOLOGY AND BIOCHEMISTRY

G-protein-coupled receptors for free fatty acids: nutritional and therapeutic targets

(2014) Graeme Milligan et al.   BRITISH JOURNAL OF NUTRITION

The Effects of Propionate and Valerate on Insulin Responsiveness for Glucose Uptake in 3T3-L1 Adipocytes and C2C12 Myotubes via G Protein-Coupled Receptor 41

(2014) Joo-Hui Han et al.   PLoS One

Treatment of Type 2 Diabetes by Free Fatty Acid Receptor Agonists

(2014) Kenneth R. Watterson et al.   Frontiers in Endocrinology

Medium-chain Fatty Acid-sensing Receptor, GPR84, Is a Proinflammatory Receptor

(2013) Masakatsu Suzuki et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Omega 3 Fatty Acids and GPR120

(2012) Da Young Oh et al.   Cell Metabolism

Inflammatory changes in adipose tissue enhance expression of GPR84, a medium-chain fatty acid receptor

(2012) Hiroshi Nagasaki et al.   FEBS LETTERS

Dysfunction of lipid sensor GPR120 leads to obesity in both mouse and human

(2012) Atsuhiko Ichimura et al.   NATURE

Short-Chain Fatty Acids Stimulate Glucagon-Like Peptide-1 Secretion via the G-Protein-Coupled Receptor FFAR2

(2011) G. Tolhurst et al.   DIABETES

Fatty acids and inflammation: The cutting edge between food and pharma

(2011) Philip C. Calder   EUROPEAN JOURNAL OF PHARMACOLOGY

Macrophage-induced expression and release of matrix metalloproteinase 1 and 3 by human preadipocytes is mediated by IL-1β via activation of MAPK signaling

(2011) Dan Gao et al.   JOURNAL OF CELLULAR PHYSIOLOGY

GPR120 Is an Omega-3 Fatty Acid Receptor Mediating Potent Anti-inflammatory and Insulin-Sensitizing Effects

(2010) Da Young Oh et al.   CELL

Roles of GPR41 and GPR43 in leptin secretory responses of murine adipocytes to short chain fatty acids

(2010) Mohamed S. Zaibi et al.   FEBS LETTERS

Adipose Tissue Dysfunction in Obesity

(2009) M. Blüher   EXPERIMENTAL AND CLINICAL ENDOCRINOLOGY & DIABETES

Microarray analysis identifies matrix metalloproteinases (MMPs) as key genes whose expression is up-regulated in human adipocytes by macrophage-conditioned medium

(2009) Adrian O’Hara et al.   PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY