Cytotoxicological pathways induced after nanoparticle exposure: studies of oxidative stress at the ‘nano–bio’ interface

In vitro and in vivo evaluation of the toxicities induced by metallic nickel nano and fine particles

(2016) Ruth Magaye et al.   JOURNAL OF MOLECULAR HISTOLOGY

Effect of the surface modification, size, and shape on cellular uptake of nanoparticles

(2015) Sara Salatin et al.   CELL BIOLOGY INTERNATIONAL

Toxicokinetics and toxicodynamics of differently coated silver nanoparticles and silver nitrate inEnchytraeus crypticusupon aqueous exposure in an inert sand medium

(2015) Emel Topuz et al.   ENVIRONMENTAL TOXICOLOGY AND CHEMISTRY

Effects of silver nanoparticles and gold nanoparticles on IL-2, IL-6, and TNF-α production via MAPK pathway in leukemic cell lines

(2015) C. Parnsamut et al.   GENETICS AND MOLECULAR RESEARCH

Silica nanoparticles induce oxidative stress, inflammation, and endothelial dysfunction in vitro via activation of the MAPK/Nrf2 pathway and nuclear factor-κB signaling

(2015) Caixia Guo et al.   International Journal of Nanomedicine

Particle uptake efficiency is significantly affected by type of capping agent and cell line

(2015) Fan Zhang et al.   JOURNAL OF APPLIED TOXICOLOGY

Cobalt oxide nanoparticles induced oxidative stress linked to activation of TNF-α/caspase-8/p38-MAPK signaling in human leukemia cells

(2015) Sourav Chattopadhyay et al.   JOURNAL OF APPLIED TOXICOLOGY

Nanotechnology in the real world: Redeveloping the nanomaterial consumer products inventory

(2015) Marina E Vance et al.   Beilstein Journal of Nanotechnology

Nrf2 protects the lung against inflammation induced by titanium dioxide nanoparticles: A positive regulator role of Nrf2 on cytokine release

(2014) Norma L. Delgado-Buenrostro et al.   ENVIRONMENTAL TOXICOLOGY

Size-dependent cytotoxicity of silver nanoparticles in human lung cells: the role of cellular uptake, agglomeration and Ag release

(2014) Anda R Gliga et al.   Particle and Fibre Toxicology

Silver nanoparticles induced changes in the expression of NF-κB related genes are cell type specific and related to the basal activity of NF-κB

(2014) T.M. Stępkowski et al.   TOXICOLOGY IN VITRO

ERK pathway is activated in bare-FeNPs-induced autophagy

(2013) Eun-Jung Park et al.   ARCHIVES OF TOXICOLOGY

Tox21 to Date: Steps toward Modernizing Human Hazard Characterization

(2013) Kellyn S. Betts   ENVIRONMENTAL HEALTH PERSPECTIVES

Renal Injury and Nrf2 Modulation in Mouse Kidney Following Chronic Exposure to TiO2 Nanoparticles

(2013) Suxin Gui et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Predictive value of in vitro assays depends on the mechanism of toxicity of metal oxide nanoparticles

(2013) Wan-Seob Cho et al.   Particle and Fibre Toxicology

Multi-walled carbon nanotubes induce human microvascular endothelial cellular effects in an alveolar-capillary co-culture with small airway epithelial cells

(2013) Brandi N Snyder-Talkington et al.   Particle and Fibre Toxicology

Zinc Oxide Nanoparticles Induce Necrosis and Apoptosis in Macrophages in a p47phox- and Nrf2-Independent Manner

(2013) Verena Wilhelmi et al.   PLoS One

Toxic Effect of Silica Nanoparticles on Endothelial Cells through DNA Damage Response via Chk1-Dependent G2/M Checkpoint

(2013) Junchao Duan et al.   PLoS One

A long-term three dimensional liver co-culture system for improved prediction of clinically relevant drug-induced hepatotoxicity

(2013) Radina Kostadinova et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Mechanistic study on the biological effects of silver and gold nanoparticles in Caco-2 cells – Induction of the Nrf2/HO-1 pathway by high concentrations of silver nanoparticles

(2013) Sasitorn Aueviriyavit et al.   TOXICOLOGY LETTERS

The Effect of Nanoparticle Size, Shape, and Surface Chemistry on Biological Systems

(2012) Alexandre Albanese et al.   Annual Review of Biomedical Engineering

Effects of surface functional groups on the formation of nanoparticle-protein corona

(2012) R. Podila et al.   APPLIED PHYSICS LETTERS

Surface functionalization of nanoparticles for nanomedicine

(2012) Rubul Mout et al.   CHEMICAL SOCIETY REVIEWS

Nrf2-regulated phase II enzymes are induced by chronic ambient nanoparticle exposure in young mice with age-related impairments

(2012) Hongqiao Zhang et al.   FREE RADICAL BIOLOGY AND MEDICINE

Biomolecular coronas provide the biological identity of nanosized materials

(2012) Marco P. Monopoli et al.   Nature Nanotechnology

Placebo-Controlled Phase 3 Study of Oral BG-12 for Relapsing Multiple Sclerosis

(2012) Ralf Gold et al.   NEW ENGLAND JOURNAL OF MEDICINE

Comparative cytological responses of lung epithelial and pleural mesothelial cells following in vitro exposure to nanoscale SiO2

(2012) J. Michael Berg et al.   TOXICOLOGY IN VITRO

Distinct immunomodulatory effects of a panel of nanomaterials in human dermal fibroblasts

(2012) Amelia A. Romoser et al.   TOXICOLOGY LETTERS

Silver nanoparticles-mediated G2/M cycle arrest of renal epithelial cells is associated with NRF2-GSH signaling

(2012) Su Jin Kang et al.   TOXICOLOGY LETTERS

Genotoxicity and molecular response of silver nanoparticle (NP)-based hydrogel

(2012) Liming Xu et al.   JOURNAL OF NANOBIOTECHNOLOGY

Co-culture systems for vascularization — Learning from nature

(2011) C. James Kirkpatrick et al.   ADVANCED DRUG DELIVERY REVIEWS

Molecular mechanisms of the Keap1-Nrf2 pathway in stress response and cancer evolution

(2011) Keiko Taguchi et al.   GENES TO CELLS

Magnetite (Fe3O4) nanocrystals affect the expression of genes involved in the TGF-beta signalling pathway

(2011) Jameel Ahmad Khan et al.   Molecular BioSystems

Quantum dots trigger immunomodulation of the NFκB pathway in human skin cells

(2011) Amelia A. Romoser et al.   MOLECULAR IMMUNOLOGY

Role of the Nrf2-heme oxygenase-1 pathway in silver nanoparticle-mediated cytotoxicity

(2011) Su Jin Kang et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Silver nanoparticles down-regulate Nrf2-mediated 8-oxoguanine DNA glycosylase 1 through inactivation of extracellular regulated kinase and protein kinase B in human Chang liver cells

(2011) Mei Jing Piao et al.   TOXICOLOGY LETTERS

Gold Nanoparticles Promote Osteogenic Differentiation of Mesenchymal Stem Cells through p38 MAPK Pathway

(2010) Changqing Yi et al.   ACS Nano

Penetration of Lipid Membranes by Gold Nanoparticles: Insights into Cellular Uptake, Cytotoxicity, and Their Relationship

(2010) Jiaqi Lin et al.   ACS Nano

Endothelial cells dysfunction induced by silica nanoparticles through oxidative stress via JNK/P53 and NF-κB pathways

(2010) Xin Liu et al.   BIOMATERIALS

Strategies for the intracellular delivery of nanoparticles

(2010) Leo Y. T. Chou et al.   CHEMICAL SOCIETY REVIEWS

p38 MAPK Activation, DNA Damage, Cell Cycle Arrest and Apoptosis As Mechanisms of Toxicity of Silver Nanoparticles in Jurkat T Cells

(2010) Hyun-Jeong Eom et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

Ion Release Kinetics and Particle Persistence in Aqueous Nano-Silver Colloids

(2010) Jingyu Liu et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

Adverse outcome pathways: A conceptual framework to support ecotoxicology research and risk assessment

(2010) Gerald T. Ankley et al.   ENVIRONMENTAL TOXICOLOGY AND CHEMISTRY

Nuclear Translocation of Nrf2 and Expression of Antioxidant Defence Genes in THP-1 Cells Exposed to Carbon Nanotubes

(2010) David M. Brown et al.   Journal of Biomedical Nanotechnology

A review of the antibacterial effects of silver nanomaterials and potential implications for human health and the environment

(2010) Catalina Marambio-Jones et al.   JOURNAL OF NANOPARTICLE RESEARCH

The rise and rise of stealth nanocarriers for cancer therapy: passive versus active targeting

(2010) Ngoc Trinh Huynh et al.   Nanomedicine

Carbon black and titanium dioxide nanoparticles elicit distinct apoptotic pathways in bronchial epithelial cells

(2010) Salik Hussain et al.   Particle and Fibre Toxicology

Surface modification, functionalization and bioconjugation of colloidal inorganic nanoparticles

(2010) R. A. Sperling et al.   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY A-MATHEMATICAL PHYSICAL AND ENGINEERING SCIENCES

Titanium dioxide nanoparticles cause apoptosis in BEAS-2B cells through the caspase 8/t-Bid-independent mitochondrial pathway

(2010) Yongli Shi et al.   TOXICOLOGY LETTERS

Involvement of JNK and P53 activation in G2/M cell cycle arrest and apoptosis induced by titanium dioxide nanoparticles in neuron cells

(2010) Jie Wu et al.   TOXICOLOGY LETTERS

Impact of Nanotechnology on Drug Delivery

(2009) Omid C. Farokhzad et al.   ACS Nano

The Nrf2-Antioxidant Response Element Signaling Pathway and Its Activation by Oxidative Stress

(2009) Truyen Nguyen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Titanium Dioxide (TiO2) Nanoparticles Induce JB6 Cell Apoptosis Through Activation of the Caspase-8/Bid and Mitochondrial Pathways

(2009) Jinshun Zhao et al.   JOURNAL OF TOXICOLOGY AND ENVIRONMENTAL HEALTH-PART A-CURRENT ISSUES

The influence of surface functionalization on the enhanced internalization of magnetic nanoparticles in cancer cells

(2009) Angeles Villanueva et al.   NANOTECHNOLOGY

Gold nanoparticle sensitize radiotherapy of prostate cancer cells by regulation of the cell cycle

(2009) Wilson Roa et al.   NANOTECHNOLOGY

Cytotoxicity and oxidative DNA damage by nanoparticles in human intestinal Caco-2 cells

(2009) Kirsten Gerloff et al.   Nanotoxicology

Silver nanoparticles induce cytotoxicity by a Trojan-horse type mechanism

(2009) Eun-Jung Park et al.   TOXICOLOGY IN VITRO

Oxidative stress of CeO2 nanoparticles via p38-Nrf-2 signaling pathway in human bronchial epithelial cell, Beas-2B

(2009) Hyun-Jeong Eom et al.   TOXICOLOGY LETTERS

The Nuclear Factor NF- B Pathway in Inflammation

(2009) T. Lawrence   Cold Spring Harbor Perspectives in Biology

Metallic nickel nano- and fine particles induce JB6 cell apoptosis through a caspase-8/AIF mediated cytochrome c-independent pathway

(2009) Jinshun Zhao et al.   JOURNAL OF NANOBIOTECHNOLOGY

Comparison of the Mechanism of Toxicity of Zinc Oxide and Cerium Oxide Nanoparticles Based on Dissolution and Oxidative Stress Properties

(2008) Tian Xia et al.   ACS Nano

Size-Dependent Endocytosis of Nanoparticles

(2008) Sulin Zhang et al.   ADVANCED MATERIALS

Titanium dioxide nanoparticles trigger p53-mediated damage response in peripheral blood lymphocytes

(2008) Su Jin Kang et al.   ENVIRONMENTAL AND MOLECULAR MUTAGENESIS

Raw Single-Wall Carbon Nanotubes Induce Oxidative Stress and Activate MAPKs, AP-1, NF-κB, and Akt in Normal and Malignant Human Mesothelial Cells

(2008) Maricica Pacurari et al.   ENVIRONMENTAL HEALTH PERSPECTIVES

Comparative study of cytotoxicity, oxidative stress and genotoxicity induced by four typical nanomaterials: the role of particle size, shape and composition

(2008) Hui Yang et al.   JOURNAL OF APPLIED TOXICOLOGY

Surface-structure-regulated cell-membrane penetration by monolayer-protected nanoparticles

(2008) Ayush Verma et al.   NATURE MATERIALS

Nanoparticle size and surface properties determine the protein corona with possible implications for biological impacts

(2008) M. Lundqvist et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA