Lamin A and microtubules collaborate to maintain nuclear morphology

Squish and squeeze — the nucleus as a physical barrier during migration in confined environments

(2016) Alexandra Lynn McGregor et al.   CURRENT OPINION IN CELL BIOLOGY

Interruption of progerin–lamin A/C binding ameliorates Hutchinson-Gilford progeria syndrome phenotype

(2016) Su-Jin Lee et al.   JOURNAL OF CLINICAL INVESTIGATION

Physical role for the nucleus in cell migration

(2016) Antoine Fruleux et al.   JOURNAL OF PHYSICS-CONDENSED MATTER

Comparing lamin proteins post-translational relative stability using a 2A peptide-based system reveals elevated resistance of progerin to cellular degradation

(2016) Di Wu et al.   Nucleus

Comparing lamin proteins post-translational relative stability using a 2A peptide-based system reveals elevated resistance of progerin to cellular degradation

(2016) Di Wu et al.   Nucleus

Automated image analysis of nuclear shape: What can we learn from a prematurely aged cell?

(2016) Meghan K. Driscoll et al.   Aging-US

Loss of H3K9me3 Correlates with ATM Activation and Histone H2AX Phosphorylation Deficiencies in Hutchinson-Gilford Progeria Syndrome

(2016) Haoyue Zhang et al.   PLoS One

Methylene blue alleviates nuclear and mitochondrial abnormalities in progeria

(2015) Zheng-Mei Xiong et al.   AGING CELL

Accessorizing and anchoring the LINC complex for multifunctionality

(2015) Wakam Chang et al.   JOURNAL OF CELL BIOLOGY

Tight coupling between nucleus and cell migration through the perinuclear actin cap

(2014) D.-H. Kim et al.   JOURNAL OF CELL SCIENCE

Chemical Inhibition of NAT10 Corrects Defects of Laminopathic Cells

(2014) D. Larrieu et al.   SCIENCE

Nuclear localization signal deletion mutants of lamin A and progerin reveal insights into lamin A processing and emerin targeting

(2014) Di Wu et al.   Nucleus

Mechanical model of blebbing in nuclear lamin meshworks

(2013) Chloe M. Funkhouser et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Nuclear Lamin-A Scales with Tissue Stiffness and Enhances Matrix-Directed Differentiation

(2013) J. Swift et al.   SCIENCE

Broken nuclei – lamins, nuclear mechanics, and disease

(2013) Patricia M. Davidson et al.   TRENDS IN CELL BIOLOGY

From Cellular Characteristics to Disease Diagnosis: Uncovering Phenotypes with Supercells

(2013) Julián Candia et al.   PLoS Computational Biology

Rapamycin activates autophagy in Hutchinson-Gilford progeria syndrome

(2012) John J. Graziotto et al.   Autophagy

Correlated alterations in genome organization, histone methylation, and DNA-lamin A/C interactions in Hutchinson-Gilford progeria syndrome

(2012) R. P. McCord et al.   GENOME RESEARCH

‘Poking’ microtubules bring about nuclear wriggling to position nuclei

(2012) Szilard Szikora et al.   JOURNAL OF CELL SCIENCE

Growing Microtubules Push the Oocyte Nucleus to Polarize the Drosophila Dorsal-Ventral Axis

(2012) T. Zhao et al.   SCIENCE

Nesprin-3: a versatile connector between the nucleus and the cytoskeleton

(2011) Mirjam Ketema et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Progerin and telomere dysfunction collaborate to trigger cellular senescence in normal human fibroblasts

(2011) Kan Cao et al.   JOURNAL OF CLINICAL INVESTIGATION

Highlights of the 2007 Progeria Research Foundation Scientific Workshop: Progress in Translational Science

(2011) L. B. Gordon et al.   JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES

Mouse B-Type Lamins Are Required for Proper Organogenesis But Not by Embryonic Stem Cells

(2011) Y. Kim et al.   SCIENCE

Rapamycin Reverses Cellular Phenotypes and Enhances Mutant Protein Clearance in Hutchinson-Gilford Progeria Syndrome Cells

(2011) K. Cao et al.   Science Translational Medicine

Defective Lamin A-Rb Signaling in Hutchinson-Gilford Progeria Syndrome and Reversal by Farnesyltransferase Inhibition

(2010) Jackleen Marji et al.   PLoS One

Nesprin 4 is an outer nuclear membrane protein that can induce kinesin-mediated cell polarization

(2009) K. J. Roux et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A new model for nuclear lamina organization

(2008) Martin W. Goldberg et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Dysfunctional Connections Between the Nucleus and the Actin and Microtubule Networks in Laminopathic Models

(2008) Christopher M. Hale et al.   BIOPHYSICAL JOURNAL

Nuclear Shape, Mechanics, and Mechanotransduction

(2008) Kris Noel Dahl et al.   CIRCULATION RESEARCH

The A- and B-type nuclear lamin networks: microdomains involved in chromatin organization and transcription

(2008) T. Shimi et al.   GENES & DEVELOPMENT

Nuclear lamins: major factors in the structural organization and function of the nucleus and chromatin

(2008) T. Dechat et al.   GENES & DEVELOPMENT

Dynein drives nuclear rotation during forward progression of motile fibroblasts

(2008) J. R. Levy et al.   JOURNAL OF CELL SCIENCE

Phenotype and Course of Hutchinson–Gilford Progeria Syndrome

(2008) Melissa A. Merideth et al.   NEW ENGLAND JOURNAL OF MEDICINE

A farnesyltransferase inhibitor prevents both the onset and late progression of cardiovascular disease in a progeria mouse model

(2008) B. C. Capell et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA