Hypermethylation of MIR21 in CD4+ T cells from patients with relapsing-remitting multiple sclerosis associates with lower miRNA-21 levels and concomitant up-regulation of its target genes

Interactions between genetic, lifestyle and environmental risk factors for multiple sclerosis

(2016) Tomas Olsson et al.   Nature Reviews Neurology

SncRNA (microRNA & snoRNA) opposite expression pattern found in multiple sclerosis relapse and remission is sex dependent

(2016) Maider Muñoz-Culla et al.   Scientific Reports

5-Hydroxymethylcytosine Remodeling Precedes Lineage Specification during Differentiation of Human CD4 + T Cells

(2016) Colm E. Nestor et al.   Cell Reports

DNA methylation changes of whole blood cells in response to active smoking exposure in adults: a systematic review of DNA methylation studies

(2015) Xu Gao et al.   Clinical Epigenetics

Genome-Wide DNA Methylation Profiles Indicate CD8+ T Cell Hypermethylation in Multiple Sclerosis

(2015) Steffan D. Bos et al.   PLoS One

miR-21 is a negative modulator of T-cell activation

(2014) Claudia Carissimi et al.   BIOCHIMIE

Epigenome-Wide Association Study of Fasting Blood Lipids in the Genetics of Lipid-Lowering Drugs and Diet Network Study

(2014) Marguerite R. Irvin et al.   CIRCULATION

Expression, Regulation and Function of MicroRNAs in Multiple Sclerosis

(2014) Xinting Ma et al.   International Journal of Medical Sciences

Decreased expression of microRNA-21 correlates with the imbalance of Th17 and Treg cells in patients with rheumatoid arthritis

(2014) Liyang Dong et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Regulation of T lymphocyte activation by microRNA-21

(2014) Lu Wang et al.   MOLECULAR IMMUNOLOGY

DNA Methylation in Mammals

(2014) E. Li et al.   Cold Spring Harbor Perspectives in Biology

Genome-wide DNA methylation analysis identifies hypomethylated genes regulated by FOXP3 in human regulatory T cells

(2013) Y. Zhang et al.   BLOOD

SNPs located at CpG sites modulate genome-epigenome interaction

(2013) Degui Zhi et al.   Epigenetics

The Bcl6 target gene microRNA-21 promotes Th2 differentiation by a T cell intrinsic pathway

(2013) Deepali V. Sawant et al.   MOLECULAR IMMUNOLOGY

Methylation differences at the HLA-DRB1 locus in CD4+ T-Cells are associated with multiple sclerosis

(2013) MC Graves et al.   Multiple Sclerosis Journal

Epigenome-wide association data implicate DNA methylation as an intermediary of genetic risk in rheumatoid arthritis

(2013) Yun Liu et al.   NATURE BIOTECHNOLOGY

Analysis of immune-related loci identifies 48 new susceptibility variants for multiple sclerosis

(2013) Ashley H Beecham et al.   NATURE GENETICS

Janus-like opposing roles of CD47 in autoimmune brain inflammation in humans and mice

(2012) May H. Han et al.   JOURNAL OF EXPERIMENTAL MEDICINE

A genome-wide association study of inflammatory biomarker changes in response to fenofibrate treatment in the Genetics of Lipid Lowering Drug and Diet Network

(2012) Stella Aslibekyan et al.   Pharmacogenetics and Genomics

Dihydroceramide-based Response to Hypoxia

(2011) Cecilia M. Devlin et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis

(2011) Stephen Sawcer et al.   NATURE

Distinct microRNA signatures in human lymphocyte subsets and enforcement of the naive state in CD4+ T cells by the microRNA miR-125b

(2011) Riccardo L Rossi et al.   NATURE IMMUNOLOGY

Expression and genetic analysis of miRNAs involved in CD4+ cell activation in patients with multiple sclerosis

(2011) Chiara Fenoglio et al.   NEUROSCIENCE LETTERS

Human natural Treg microRNA signature: Role of microRNA‐31 and microRNA‐21 in FOXP3 expression

(2009) Redouane Rouas et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Multiple sclerosis

(2008) Alastair Compston et al.   LANCET