Dynamic silencing of somatic L1 retrotransposon insertions reflects the developmental and cellular contexts of their genomic integration

A hot L1 retrotransposon evades somatic repression and initiates human colorectal cancer

(2016) Emma C. Scott et al.   GENOME RESEARCH

Deciphering fact from artifact when using reporter assays to investigate the roles of host factors on L1 retrotransposition

(2016) Pamela R. Cook et al.   Mobile DNA

Retrotransposition creates sloping shores: a graded influence of hypomethylated CpG islands on flanking CpG sites

(2015) Fiorella C. Grandi et al.   GENOME RESEARCH

Genetic and epigenetic variation among inbred mouse littermates: identification of inter-individual differentially methylated regions

(2015) Harald Oey et al.   Epigenetics & Chromatin

Two waves of de novo methylation during mouse germ cell development

(2014) A. Molaro et al.   GENES & DEVELOPMENT

piRNA pathway targets active LINE1 elements to establish the repressive H3K9me3 mark in germ cells

(2014) D. Pezic et al.   GENES & DEVELOPMENT

An antisense promoter in mouse L1 retrotransposon open reading frame-1 initiates expression of diverse fusion transcripts and limits retrotransposition

(2014) Jingfeng Li et al.   NUCLEIC ACIDS RESEARCH

Characterization of Constitutive Promoters for piggyBac Transposon-Mediated Stable Transgene Expression in Mesenchymal Stem Cells (MSCs)

(2014) Sheng Wen et al.   PLoS One

Extensive transduction of nonrepetitive DNA mediated by L1 retrotransposition in cancer genomes

(2014) J. M. C. Tubio et al.   SCIENCE

How do mammalian transposons induce genetic variation? A conceptual framework

(2013) Keiko Akagi et al.   BIOESSAYS

Kinetics and Epigenetics of Retroviral Silencing in Mouse Embryonic Stem Cells Defined by Deletion of the D4Z4 Element

(2013) Sylvie Rival-Gervier et al.   MOLECULAR THERAPY

Signatures of mutational processes in human cancer

(2013) Ludmil B. Alexandrov et al.   NATURE

piggyBac Transposon plus Insulators Overcome Epigenetic Silencing to Provide for Stable Signaling Pathway Reporter Cell Lines

(2013) Valeri V. Mossine et al.   PLoS One

Transposable Elements Re-Wire and Fine-Tune the Transcriptome

(2013) Michael Cowley et al.   PLoS Genetics

Single-Neuron Sequencing Analysis of L1 Retrotransposition and Somatic Mutation in the Human Brain

(2012) Gilad D. Evrony et al.   CELL

Retrotransposons as a major source of epigenetic variations in the mammalian genome

(2012) Muhammad B. Ekram et al.   Epigenetics

Mouse endogenous retroviruses can trigger premature transcriptional termination at a distance

(2012) J. Li et al.   GENOME RESEARCH

Landscape of Somatic Retrotransposition in Human Cancers

(2012) E. Lee et al.   SCIENCE

Genome-wide target profiling of piggyBac and Tol2 in HEK 293: pros and cons for gene discovery and gene therapy

(2011) Yaa-Jyuhn J Meir et al.   BMC BIOTECHNOLOGY

Genome Sequencing of Mouse Induced Pluripotent Stem Cells Reveals Retroelement Stability and Infrequent DNA Rearrangement during Reprogramming

(2011) Aaron R. Quinlan et al.   Cell Stem Cell

Reprogramming somatic cells into iPS cells activates LINE-1 retroelement mobility

(2011) Silke Wissing et al.   HUMAN MOLECULAR GENETICS

Somatic retrotransposition alters the genetic landscape of the human brain

(2011) J. Kenneth Baillie et al.   NATURE

Dynamic interactions between transposable elements and their hosts

(2011) Henry L. Levin et al.   NATURE REVIEWS GENETICS

Intronic L1 Retrotransposons and Nested Genes Cause Transcriptional Interference by Inducing Intron Retention, Exonization and Cryptic Polyadenylation

(2011) Kristel Kaer et al.   PLoS One

Epigenetic consequences of foreign DNA insertions: de novo methylation and global alterations of methylation patterns in recipient genomes

(2011) Walter Doerfler   REVIEWS IN MEDICAL VIROLOGY

Natural Mutagenesis of Human Genomes by Endogenous Retrotransposons

(2010) Rebecca C. Iskow et al.   CELL

Epigenetic Control of Retrotransposon Expression in Human Embryonic Stem Cells

(2010) A. Macia et al.   MOLECULAR AND CELLULAR BIOLOGY

piggyBac Transposon-mediated Long-term Gene Expression in Mice

(2010) Hideyuki Nakanishi et al.   MOLECULAR THERAPY

Epigenetic silencing of engineered L1 retrotransposition events in human embryonic carcinoma cells

(2010) Jose L. Garcia-Perez et al.   NATURE

Characterization of L1 retrotransposition with high-throughput dual-luciferase assays

(2010) Yi Xie et al.   NUCLEIC ACIDS RESEARCH

L1 retrotransposition in human neural progenitor cells

(2009) Nicole G. Coufal et al.   NATURE

The impact of multiple splice sites in human L1 elements

(2008) V.P. Belancio et al.   GENE

Conditional activation of a single-copy L1 transgene in mice by Cre

(2008) Wenfeng An et al.   GENESIS

Extensive variation between inbred mouse strains due to endogenous L1 retrotransposition

(2008) K. Akagi et al.   GENOME RESEARCH