Silica-based nanoparticles for therapeutic protein delivery

Anion Assisted Synthesis of Large Pore Hollow Dendritic Mesoporous Organosilica Nanoparticles: Understanding the Composition Gradient

(2016) Yannan Yang et al.   CHEMISTRY OF MATERIALS

Structure-Dependent and Glutathione-Responsive Biodegradable Dendritic Mesoporous Organosilica Nanoparticles for Safe Protein Delivery

(2016) Yannan Yang et al.   CHEMISTRY OF MATERIALS

Silica Nanopollens Enhance Adhesion for Long-Term Bacterial Inhibition

(2016) Hao Song et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

A Vesicle Supra-Assembly Approach to Synthesize Amine-Functionalized Hollow Dendritic Mesoporous Silica Nanospheres for Protein Delivery

(2016) Anand Kumar Meka et al.   Small

Nanocaged enzymes with enhanced catalytic activity and increased stability against protease digestion

(2016) Zhao Zhao et al.   Nature Communications

Understanding the contribution of surface roughness and hydrophobic modification of silica nanoparticles to enhanced therapeutic protein delivery

(2016) Yuting Niu et al.   Journal of Materials Chemistry B

Hybrid Mesoporous Silica-Based Drug Carrier Nanostructures with Improved Degradability by Hydroxyapatite

(2015) Xiaohong Hao et al.   ACS Nano

Self-Organized Mesostructured Hollow Carbon Nanoparticles via a Surfactant-Free Sequential Heterogeneous Nucleation Pathway

(2015) Hongwei Zhang et al.   CHEMISTRY OF MATERIALS

DNA-Mediated Cellular Delivery of Functional Enzymes

(2015) Jeffrey D. Brodin et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Natural and Synthetic Polymers as Drug Carriers for Delivery of Therapeutic Proteins

(2015) Muhammad Sajid Hamid Akash et al.   Polymer Reviews

Biphasic Synthesis of Large-Pore and Well-Dispersed Benzene Bridged Mesoporous Organosilica Nanoparticles for Intracellular Protein Delivery

(2015) Yannan Yang et al.   Small

Core-Cone Structured Monodispersed Mesoporous Silica Nanoparticles with Ultra-large Cavity for Protein Delivery

(2015) Chun Xu et al.   Small

Synthesis of silica nanoparticles with controllable surface roughness for therapeutic protein delivery

(2015) Yuting Niu et al.   Journal of Materials Chemistry B

Enzyme Encapsulated Hollow Silica Nanospheres for Intracellular Biocatalysis

(2014) Feng-Peng Chang et al.   ACS Applied Materials & Interfaces

Biodegradable Ethylene-Bis(Propyl)Disulfide-Based Periodic Mesoporous Organosilica Nanorods and Nanospheres for Efficient In-Vitro Drug Delivery

(2014) Jonas Croissant et al.   ADVANCED MATERIALS

Development and Applications of CRISPR-Cas9 for Genome Engineering

(2014) Patrick D. Hsu et al.   CELL

Emerging micro- and nanotechnology based synthetic approaches for insulin delivery

(2014) Ran Mo et al.   CHEMICAL SOCIETY REVIEWS

Stimuli-responsive nanomaterials for therapeutic protein delivery

(2014) Yue Lu et al.   JOURNAL OF CONTROLLED RELEASE

Biphase Stratification Approach to Three-Dimensional Dendritic Biodegradable Mesoporous Silica Nanospheres

(2014) Dengke Shen et al.   NANO LETTERS

Injectable, spontaneously assembling, inorganic scaffolds modulate immune cells in vivo and increase vaccine efficacy

(2014) Jaeyun Kim et al.   NATURE BIOTECHNOLOGY

Clinical translation of an ultrasmall inorganic optical-PET imaging nanoparticle probe

(2014) E. Phillips et al.   Science Translational Medicine

Dendritic Silica Particles with Center-Radial Pore Channels: Promising Platforms for Catalysis and Biomedical Applications

(2014) Xin Du et al.   Small

Developing Functionalized Dendrimer-Like Silica Nanoparticles with Hierarchical Pores as Advanced Delivery Nanocarriers

(2013) Xin Du et al.   ADVANCED MATERIALS

Nanoparticles Mimicking Viral Surface Topography for Enhanced Cellular Delivery

(2013) Yuting Niu et al.   ADVANCED MATERIALS

Reduction-Responsive Polymeric Micelles and Vesicles for Triggered Intracellular Drug Release

(2013) Huanli Sun et al.   ANTIOXIDANTS & REDOX SIGNALING

The absorption, distribution, excretion and toxicity of mesoporous silica nanoparticles in mice following different exposure routes

(2013) Changhui Fu et al.   BIOMATERIALS

Functional Repair of CFTR by CRISPR/Cas9 in Intestinal Stem Cell Organoids of Cystic Fibrosis Patients

(2013) Gerald Schwank et al.   Cell Stem Cell

Synthesis of mesoporous silica nanoparticles

(2013) Si-Han Wu et al.   CHEMICAL SOCIETY REVIEWS

Engineering Cytochrome-Modified Silica Nanoparticles To Induce Programmed Cell Death

(2013) Wen-Yen Huang et al.   CHEMISTRY-A EUROPEAN JOURNAL

Preparation, characterization, and evaluation in vivo of Ins-SiO2-HP55 (insulin-loaded silica coating HP55) for oral delivery of insulin

(2013) Xiuhua Zhao et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Delivery of Chemically Glycosylated Cytochrome c Immobilized in Mesoporous Silica Nanoparticles Induces Apoptosis in HeLa Cancer Cells

(2013) Jessica Méndez et al.   MOLECULAR PHARMACEUTICS

Mesoporous silica nanoparticles as antigen carriers and adjuvants for vaccine delivery

(2013) Karishma T. Mody et al.   Nanoscale

Cas9 as a versatile tool for engineering biology

(2013) Prashant Mali et al.   NATURE METHODS

Oral glucose- and pH-sensitive nanocarriers for simulating insulin release in vivo

(2013) Lei Sun et al.   Polymer Chemistry

Enzyme-Coated Mesoporous Silica Nanoparticles as Efficient Antibacterial Agents In Vivo

(2013) Li-li Li et al.   Advanced Healthcare Materials

Influence of Geometry, Porosity, and Surface Characteristics of Silica Nanoparticles on Acute Toxicity: Their Vasculature Effect and Tolerance Threshold

(2012) Tian Yu et al.   ACS Nano

Diagnosis and Classification of Diabetes Mellitus

(2012)   DIABETES CARE

Cyclic AMP dynamics in the pancreatic β-cell

(2012) Anders Tengholm   UPSALA JOURNAL OF MEDICAL SCIENCES

The Shape Effect of Mesoporous Silica Nanoparticles on Biodistribution, Clearance, and Biocompatibility in Vivo

(2011) Xinglu Huang et al.   ACS Nano

Extension of The Stöber Method to the Preparation of Monodisperse Resorcinol-Formaldehyde Resin Polymer and Carbon Spheres

(2011) Jian Liu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

A glucose-responsive controlled release of insulin system based on enzyme multilayers-coated mesoporous silica particles

(2011) Wenru Zhao et al.   CHEMICAL COMMUNICATIONS

Tailoring nanocarriers for intracellular protein delivery

(2011) Zhen Gu et al.   CHEMICAL SOCIETY REVIEWS

Assessment of Net Charge and Protein–Protein Interactions of Different Monoclonal Antibodies

(2011) Christian Lehermayr et al.   JOURNAL OF PHARMACEUTICAL SCIENCES

Nanoparticle-Mediated Cytoplasmic Delivery of Proteins To Target Cellular Machinery

(2010) Shyam Sundhar Bale et al.   ACS Nano

Single and repeated dose toxicity of mesoporous hollow silica nanoparticles in intravenously exposed mice

(2010) Tianlong Liu et al.   BIOMATERIALS

Local Release of Highly Loaded Antibodies from Functionalized Nanoporous Support for Cancer Immunotherapy

(2010) Chenghong Lei et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Intracellular Delivery of a Membrane-Impermeable Enzyme in Active Form Using Functionalized Gold Nanoparticles

(2010) Partha Ghosh et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Understanding and overcoming major barriers in cancer nanomedicine

(2010) Shuming Nie   Nanomedicine

Polyethyleneimine Coating Enhances the Cellular Uptake of Mesoporous Silica Nanoparticles and Allows Safe Delivery of siRNA and DNA Constructs

(2009) Tian Xia et al.   ACS Nano

Better safe than sorry: Understanding the toxicological properties of inorganic nanoparticles manufactured for biomedical applications

(2009) Bengt Fadeel et al.   ADVANCED DRUG DELIVERY REVIEWS

Why are tumour blood vessels abnormal and why is it important to know?

(2009) J A Nagy et al.   BRITISH JOURNAL OF CANCER

Preparation of Siliceous Vesicles with Adjustable Sizes, Wall Thickness, and Shapes

(2009) Meihua Yu et al.   CHEMISTRY LETTERS

Mesoporous Silica Nanoparticle-Based Double Drug Delivery System for Glucose-Responsive Controlled Release of Insulin and Cyclic AMP

(2009) Yannan Zhao et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

A novel intracellular protein delivery platform based on single-protein nanocapsules

(2009) Ming Yan et al.   Nature Nanotechnology

Nanoscience under Glass: The Versatile Chemistry of Silica Nanostructures

(2008) Naomi J. Halas   ACS Nano

Proteins in Mesoporous Silicates

(2008) Sarah Hudson et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Intracellular Delivery of Quantum Dot−Protein Cargos Mediated by Cell Penetrating Peptides

(2008) Igor L. Medintz et al.   BIOCONJUGATE CHEMISTRY

The biocompatibility of mesoporous silicates

(2008) Sarah P. Hudson et al.   BIOMATERIALS

Protein therapeutics: a summary and pharmacological classification

(2007) Benjamin Leader et al.   NATURE REVIEWS DRUG DISCOVERY