Replacement of quaternary ammonium headgroups by tri-ornithine in cationic lipids for the improvement of gene delivery in vitro and in vivo

Synthetically controlling dendrimer flexibility improves delivery of large plasmid DNA

(2017) Jessica A. Kretzmann et al.   Chemical Science

Nuclear-targeted siRNA delivery for long-term gene silencing

(2017) Na Li et al.   Chemical Science

Viral Vector-Mediated Antisense Therapy for Genetic Diseases

(2017) Marine Imbert et al.   Genes

In Vitro and In Vivo Tumor-Targeting siRNA Delivery Using Folate-PEG-appended Dendrimer (G4)/α-Cyclodextrin Conjugates

(2016) Ayumu Ohyama et al.   BIOCONJUGATE CHEMISTRY

Effect of surface properties on liposomal siRNA delivery

(2016) Yuqiong Xia et al.   BIOMATERIALS

Syndecan-1 (CD138) Suppresses Apoptosis in Multiple Myeloma by Activating IGF1 Receptor: Prevention by SynstatinIGF1R Inhibits Tumor Growth

(2016) D. M. Beauvais et al.   CANCER RESEARCH

Polymer–DNA Molecular Net for Selective Transportation of Target Biomolecules and Inhibition of Tumor Growth

(2016) Jihyun Lee et al.   CHEMISTRY OF MATERIALS

Characterization of a novel adeno-associated viral vector with preferential oligodendrocyte tropism

(2016) S K Powell et al.   GENE THERAPY

Peptide-Mediated Tumor Targeting by a Degradable Nano Gene Delivery Vector Based on Pluronic-Modified Polyethylenimine

(2016) Zhaoyong Wu et al.   Nanoscale Research Letters

The insulin-like growth factor-I receptor (IGF-IR) in breast cancer: biology and treatment strategies

(2016) Morteza Motallebnezhad et al.   TUMOR BIOLOGY

Targeted anion transporter delivery by coiled-coil driven membrane fusion

(2016) Nestor Lopez Mora et al.   Chemical Science

Elevated expression levels of serum insulin-like growth factor-1, tumor necrosis factor-α and vascular endothelial growth factor 165 might exacerbate type 2 diabetic nephropathy

(2016) Xiang Li et al.   Journal of Diabetes Investigation

Metformin Enhances the Therapy Effects of Anti-IGF-1R mAb Figitumumab to NSCLC

(2016) Hongxin Cao et al.   Scientific Reports

Peptide-Mediated Tumor Targeting by a Degradable Nano Gene Delivery Vector Based on Pluronic-Modified Polyethylenimine

(2016) Zhaoyong Wu et al.   Nanoscale Research Letters

Cationic nanocarriers induce cell necrosis through impairment of Na+/K+-ATPase and cause subsequent inflammatory response

(2015) Xiawei Wei et al.   CELL RESEARCH

An Overview of the Prediction of Protein DNA-Binding Sites

(2015) Jingna Si et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Tri-peptide cationic lipids for gene delivery

(2015) Yinan Zhao et al.   Journal of Materials Chemistry B

Advances and Challenges of Liposome Assisted Drug Delivery

(2015) Lisa Sercombe et al.   Frontiers in Pharmacology

The Headgroup Evolution of Cationic Lipids for Gene Delivery

(2013) Defu Zhi et al.   BIOCONJUGATE CHEMISTRY

One-Step Synthesis of Nanosized and Stable Amino-Functionalized Calcium Phosphate Particles for DNA Transfection

(2013) Babak Mostaghaci et al.   CHEMISTRY OF MATERIALS

Dynamic Amphiphile Libraries To Screen for the “Fragrant” Delivery of siRNA into HeLa Cells and Human Primary Fibroblasts

(2013) Charlotte Gehin et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Intracellular Delivery of Universal Proteins Using a Lysine Headgroup Containing Cationic Liposomes: Deciphering the Uptake Mechanism

(2013) Satya Ranjan Sarker et al.   MOLECULAR PHARMACEUTICS

Lipid-mediated DNA and siRNA transfection efficiency depends on peptide headgroup

(2013) Xiao-Xiang Zhang et al.   Soft Matter

Nanomagnetic Gene Transfection for Non-Viral Gene Delivery in NIH 3T3 Mouse Embryonic Fibroblasts

(2013) Angeliki Fouriki et al.   Materials

Synthesis and Biological Response of Size-Specific, Monodisperse Drug–Silica Nanoconjugates

(2012) Li Tang et al.   ACS Nano

Synthesis and biological activity of carbamate-linked cationic lipids for gene delivery in vitro

(2012) Defu Zhi et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Nanovector delivery of siRNA for cancer therapy

(2012) H Shen et al.   CANCER GENE THERAPY

A single replacement of histidine to arginine in EGFR-lytic hybrid peptide demonstrates the improved anticancer activity

(2011) Noriko Tada et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Peptide- and Protein-Based Hydrogels

(2011) Anika M. Jonker et al.   CHEMISTRY OF MATERIALS

Gene therapy finds its niche

(2011) Cormac Sheridan   NATURE BIOTECHNOLOGY

Influence of hydroxyl groups on the biological properties of cationic polymethacrylates as gene vectors

(2010) Ming Ma et al.   Acta Biomaterialia

Transfection Efficiency of Cationic Lipids with Different Hydrophobic Domains in Gene Delivery

(2010) DeFu Zhi et al.   BIOCONJUGATE CHEMISTRY

Effects of particle size and surface charge on cellular uptake and biodistribution of polymeric nanoparticles

(2010) Chunbai He et al.   BIOMATERIALS

Medicinal Chemistry of siRNA Delivery

(2010) Matthew G. Stanton et al.   JOURNAL OF MEDICINAL CHEMISTRY

Compensatory Insulin Receptor (IR) Activation on Inhibition of Insulin-Like Growth Factor-1 Receptor (IGF-1R): Rationale for Cotargeting IGF-1R and IR in Cancer

(2010) E. Buck et al.   MOLECULAR CANCER THERAPEUTICS

Evidence of RNAi in humans from systemically administered siRNA via targeted nanoparticles

(2010) Mark E. Davis et al.   NATURE

Structure−Activity Investigation on the Gene Transfection Properties of Cardiolipin Mimicking Gemini Lipid Analogues

(2008) Avinash Bajaj et al.   BIOCONJUGATE CHEMISTRY