The Role of Oxidative Stress, Mitochondrial Function, and Autophagy in Diabetic Polyneuropathy

Mitochondrial DNA damage and vascular function in patients with diabetes mellitus and atherosclerotic cardiovascular disease

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Redox Homeostasis and Cellular Antioxidant Systems: Crucial Players in Cancer Growth and Therapy

(2016) Barbara Marengo et al.   Oxidative Medicine and Cellular Longevity

A combination dual-sized microparticle system modulates dendritic cells and prevents type 1 diabetes in prediabetic NOD mice

(2015) Jamal S. Lewis et al.   CLINICAL IMMUNOLOGY

Altered circulating mitochondrial DNA and increased inflammation in patients with diabetic retinopathy

(2015) Afshan N. Malik et al.   DIABETES RESEARCH AND CLINICAL PRACTICE

Mitochondria in the Regulation of Innate and Adaptive Immunity

(2015) Samuel E. Weinberg et al.   IMMUNITY

Flavonols in the Prevention of Diabetes-induced Vascular Dysfunction

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Antioxidant Strategies in the Management of Diabetic Neuropathy

(2015) Ayodeji Babatunde Oyenihi et al.   Biomed Research International

Mitochondrial Dynamics in Peripheral Neuropathies

(2014) Marija Sajic   ANTIOXIDANTS & REDOX SIGNALING

ER Stress in Diabetic Peripheral Neuropathy: A New Therapeutic Target

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The interplay between central metabolism and innate immune responses

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Peroxynitrite and protein nitration in the pathogenesis of diabetic peripheral neuropathy

(2014) Roman Stavniichuk et al.   DIABETES-METABOLISM RESEARCH AND REVIEWS

Diabetic Neuropathies: Diagnosis and Management

(2014) Gabriella Deli et al.   NEUROENDOCRINOLOGY

Painful diabetic neuropathy

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Balance between autophagic pathways preserves retinal homeostasis

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Kolaviron, a Garcinia biflavonoid complex ameliorates hyperglycemia-mediated hepatic injury in rats via suppression of inflammatory responses

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Neuroprotection by Resveratrol in Diabetic Neuropathy: Concepts & Mechanisms

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Oxidative Stress as an Underlying Contributor in the Development of Chronic Complications in Diabetes Mellitus

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ER Stress as a Trigger for  -Cell Dysfunction and Autoimmunity in Type 1 Diabetes

(2012) B. O'Sullivan-Murphy et al.   DIABETES

Signalling danger: endoplasmic reticulum stress and the unfolded protein response in pancreatic islet inflammation

(2012) D. L. Eizirik et al.   DIABETOLOGIA

Molecular Intricacies and the Role of ER Stress in Diabetes

(2012) Muthuswamy Balasubramanyam et al.   Experimental Diabetes Research

Apolipoprotein E knockout as the basis for mouse models of dyslipidemia-induced neuropathy

(2012) Lucy M. Hinder et al.   EXPERIMENTAL NEUROLOGY

Decreased glycolytic and tricarboxylic acid cycle intermediates coincide with peripheral nervous system oxidative stress in a murine model of type 2 diabetes

(2012) Lucy M Hinder et al.   JOURNAL OF ENDOCRINOLOGY

Evaluation of oxidative stress markers in pathogenesis of diabetic neuropathy

(2012) Jacek Kasznicki et al.   MOLECULAR BIOLOGY REPORTS

Mitochondrial DNA that escapes from autophagy causes inflammation and heart failure

(2012) Takafumi Oka et al.   NATURE

Ciliary neurotrophic factor activates NF-κB to enhance mitochondrial bioenergetics and prevent neuropathy in sensory neurons of streptozotocin-induced diabetic rodents

(2012) Ali Saleh et al.   NEUROPHARMACOLOGY

Role of phenolics as antioxidants, biomolecule protectors and as anti–diabetic factors – Evaluation on bark and empty pods of Acacia auriculiformis

(2012) Arumugam Sathya et al.   Asian Pacific Journal of Tropical Medicine

A Current Update on the Use of Alpha Lipoic Acid in the Management of Type 2 Diabetes Mellitus

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Efficacy and Safety of Antioxidant Treatment With  -Lipoic Acid Over 4 Years in Diabetic Polyneuropathy: The NATHAN 1 trial

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Integrating the mechanisms of apoptosis induced by endoplasmic reticulum stress

(2011) Ira Tabas et al.   NATURE CELL BIOLOGY

Diabetic neuropathy: cellular mechanisms as therapeutic targets

(2011) Andrea M. Vincent et al.   Nature Reviews Neurology

Road to Ruin: Targeting Proteins for Degradation in the Endoplasmic Reticulum

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Emerging role of innate immunity in organ transplantation Part II: potential of damage-associated molecular patterns to generate immunostimulatory dendritic cells

(2011) Walter G. Land   Transplantation Reviews

Endoplasmic Reticulum Stress and the Inflammatory Basis of Metabolic Disease

(2010) Gökhan S. Hotamisligil   CELL

Metformin, Independent of AMPK, Inhibits mTORC1 in a Rag GTPase-Dependent Manner

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The binary switch that controls the life and death decisions of ER stressed β cells

(2010) Christine M Oslowski et al.   CURRENT OPINION IN CELL BIOLOGY

Regulation of innate immunity by signaling pathways emerging from the endoplasmic reticulum

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Effect of Prior Intensive Insulin Treatment During the Diabetes Control and Complications Trial (DCCT) on Peripheral Neuropathy in Type 1 Diabetes During the Epidemiology of Diabetes Interventions and Complications (EDIC) Study

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The regulation of autophagy - unanswered questions

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Circulating mitochondrial DAMPs cause inflammatory responses to injury

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Oxidative stress and dysregulation of the taurine transporter in high-glucose-exposed human Schwann cells: implications for pathogenesis of diabetic neuropathy

(2009) Trevor Askwith et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Vitamin E (α-tocopherol) supplementation in diabetic rats: effects on the proximal colon

(2009) Luciana P Roldi et al.   BMC GASTROENTEROLOGY

A combined effect of dextromethorphan and melatonin on neuropathic pain behavior in rats

(2009) Shuxing Wang et al.   BRAIN RESEARCH

A Branched-Chain Amino Acid-Related Metabolic Signature that Differentiates Obese and Lean Humans and Contributes to Insulin Resistance

(2009) Christopher B. Newgard et al.   Cell Metabolism

Antioxidant Anti-Inflammatory Treatment in Type 2 Diabetes

(2009) A. Ceriello et al.   DIABETES CARE

Autophagy in human type 2 diabetes pancreatic beta cells

(2009) M. Masini et al.   DIABETOLOGIA

Calcium/calmodulin-dependent protein kinase II links ER stress with Fas and mitochondrial apoptosis pathways

(2009) Jenelle M. Timmins et al.   JOURNAL OF CLINICAL INVESTIGATION

Impaired Balance of Mitochondrial Fission and Fusion in Alzheimer's Disease

(2009) X. Wang et al.   JOURNAL OF NEUROSCIENCE

Glutaredoxin systems

(2008) Christopher Horst Lillig et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Diabetes and the peripheral nerve

(2008) Irina G. Obrosova   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Autophagy in the Pathogenesis of Disease

(2008) Beth Levine et al.   CELL

A novel function of poly(ADP-ribose) polymerase-1 in modulation of autophagy and necrosis under oxidative stress

(2008) Q Huang et al.   CELL DEATH AND DIFFERENTIATION

Aldose Reductase, Still a Compelling Target for Diabetic Neuropathy

(2008) Peter Oates   CURRENT DRUG TARGETS

γ-Tocopheryl quinone, notα-tocopheryl quinone, induces adaptive response through up-regulation of cellular glutathione and cysteine availability via activation of ATF4

(2008) Yoko Ogawa et al.   FREE RADICAL RESEARCH

Autophagy fights disease through cellular self-digestion

(2008) Noboru Mizushima et al.   NATURE

The nitrate–nitrite–nitric oxide pathway in physiology and therapeutics

(2008) Jon O. Lundberg et al.   NATURE REVIEWS DRUG DISCOVERY

Mitochondrial fragmentation in neurodegeneration

(2008) Andrew B. Knott et al.   NATURE REVIEWS NEUROSCIENCE

Preventing Mitochondrial Fission Impairs Mitochondrial Function and Leads to Loss of Mitochondrial DNA

(2008) Philippe A. Parone et al.   PLoS One

Advanced lipid peroxidation end products in oxidative damage to proteins. Potential role in diseases and therapeutic prospects for the inhibitors

(2007) A Negre-Salvayre et al.   BRITISH JOURNAL OF PHARMACOLOGY

NADPH oxidases in lung biology and pathology: Host defense enzymes, and more

(2007) Albert van der Vliet   FREE RADICAL BIOLOGY AND MEDICINE

A Golgi fragmentation pathway in neurodegeneration

(2007) Saya Nakagomi et al.   NEUROBIOLOGY OF DISEASE