Myopenia and precision (P4) medicine

The future of immune checkpoint cancer therapy after PD-1 and CTLA-4

(2017) Andrew W Hahn et al.   Immunotherapy

Dissociation of local and global skeletal muscle oxygen transport metrics in type 2 diabetes

(2017) P. Mason McClatchey et al.   JOURNAL OF DIABETES AND ITS COMPLICATIONS

Treatment of Sarcopenia with Bimagrumab: Results from a Phase II, Randomized, Controlled, Proof-of-Concept Study

(2017) Daniel Rooks et al.   JOURNAL OF THE AMERICAN GERIATRICS SOCIETY

Patient-Centered (P4) Medicine and the Older Person

(2017) John E. Morley et al.   Journal of the American Medical Directors Association

Utility of SARC-F for Assessing Physical Function in Elderly Patients With Cardiovascular Disease

(2017) Shinya Tanaka et al.   Journal of the American Medical Directors Association

Interventions for Treating Sarcopenia: A Systematic Review and Meta-Analysis of Randomized Controlled Studies

(2017) Yoshihiro Yoshimura et al.   Journal of the American Medical Directors Association

Protein Supplementation Augments Muscle Fiber Hypertrophy but Does Not Modulate Satellite Cell Content During Prolonged Resistance-Type Exercise Training in Frail Elderly

(2017) Marlou L. Dirks et al.   Journal of the American Medical Directors Association

Sarcopenia Screened by the SARC-F Questionnaire and Physical Performances of Elderly Women: A Cross-Sectional Study

(2017) Yves Rolland et al.   Journal of the American Medical Directors Association

Inflammation and sarcopenia: A systematic review and meta-analysis

(2017) Giulia Bano et al.   MATURITAS

Protein and exercise in the prevention of sarcopenia and aging

(2017) Manal A. Naseeb et al.   NUTRITION RESEARCH

Molecular mechanism of sarcopenia and cachexia: recent research advances

(2017) Kunihiro Sakuma et al.   PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY

New diagnostic index for sarcopenia in patients with cardiovascular diseases

(2017) Haruhito Harada et al.   PLoS One

FDA Approves Eteplirsen for Duchenne Muscular Dystrophy: The Next Chapter in the Eteplirsen Saga

(2017) Annemieke Aartsma-Rus et al.   Nucleic Acid Therapeutics

Beta-hydroxy-beta-methylbutyrate supplementation and skeletal muscle in healthy and muscle-wasting conditions

(2017) Milan Holeček   Journal of Cachexia Sarcopenia and Muscle

Cellular Reprogramming, Genome Editing, and Alternative CRISPR Cas9 Technologies for Precise Gene Therapy of Duchenne Muscular Dystrophy

(2017) Peter Gee et al.   Stem Cells International

Altered S-nitrosylation of p53 is responsible for impaired antioxidant response in skeletal muscle during aging

(2016) Sara Baldelli et al.   Aging-US

Mucocutaneous Telangiectasia as a Diagnostic Clue of Hereditary Hemorrhagic Telangiectasia: An Activin Receptor-Like Kinase-1 Mutation in a Korean Patient

(2016) Jimyung Seo et al.   Annals of Dermatology

A Single CRISPR-Cas9 Deletion Strategy that Targets the Majority of DMD Patients Restores Dystrophin Function in hiPSC-Derived Muscle Cells

(2016) Courtney S. Young et al.   Cell Stem Cell

The mTOR Conundrum: Essential for Muscle Function, but Dangerous for Survival

(2016) John E. Morley   Journal of the American Medical Directors Association

Impacts of High-Protein Oral Nutritional Supplements Among Malnourished Men and Women with Sarcopenia: A Multicenter, Randomized, Double-Blinded, Controlled Trial

(2016) Joel T. Cramer et al.   Journal of the American Medical Directors Association

Enhancing SARC-F: Improving Sarcopenia Screening in the Clinical Practice

(2016) Thiago Gonzalez Barbosa-Silva et al.   Journal of the American Medical Directors Association

Sarcopenia Screened With SARC-F Questionnaire Is Associated With Quality of Life and 4-Year Mortality

(2016) Tai-Yin Wu et al.   Journal of the American Medical Directors Association

Cross-Cultural Adaptation and Validation of the Spanish-Language Version of the SARC-F to Assess Sarcopenia in Mexican Community-Dwelling Older Adults

(2016) Lorena Parra-Rodríguez et al.   Journal of the American Medical Directors Association

Frailty and Sarcopenia as Predictors of Adverse Health Outcomes in Persons With Diabetes Mellitus

(2016) Anthony P. Liccini et al.   Journal of the American Medical Directors Association

Sarcopenia Is Recognized as an Independent Condition by an International Classification of Disease, Tenth Revision, Clinical Modification (ICD-10-CM) Code

(2016) Li Cao et al.   Journal of the American Medical Directors Association

CRISPR-mediated Genome Editing Restores Dystrophin Expression and Function in mdx Mice

(2016) Li Xu et al.   MOLECULAR THERAPY

The CRISPR Way to Think about Duchenne’s

(2016) Michele P. Calos   NEW ENGLAND JOURNAL OF MEDICINE

Effects of Testosterone Treatment in Older Men

(2016) Peter J. Snyder et al.   NEW ENGLAND JOURNAL OF MEDICINE

Welcome to the ICD-10 code for sarcopenia

(2016) Stefan D. Anker et al.   Journal of Cachexia Sarcopenia and Muscle

Effects of testosterone on lean mass gain in elderly men: systematic review with meta-analysis of controlled and randomized studies

(2015) Walter Krause Neto et al.   AGE

Regulation of skeletal muscle capillary growth in exercise and disease

(2015) Tara L. Haas et al.   Applied Physiology Nutrition and Metabolism

Pharmacologic Options for the Treatment of Sarcopenia

(2015) John E. Morley   CALCIFIED TISSUE INTERNATIONAL

C-Terminal Agrin Fragment (CAF) Reflects Renal Function in Patients Suffering from Severe Sepsis or Septic Shock

(2015) Michael Drey et al.   Clinical Laboratory

Heterogeneity of Muscle Blood Flow and Metabolism

(2015) Ilkka Heinonen et al.   EXERCISE AND SPORT SCIENCES REVIEWS

Prevalence of sarcopenia in acute hip fracture patients and its influence on short-term clinical outcome

(2015) Juan I González-Montalvo et al.   Geriatrics & Gerontology International

Instruments to Assess Sarcopenia and Physical Frailty in Older People Living in a Community (Care) Setting: Similarities and Discrepancies

(2015) Donja M. Mijnarends et al.   Journal of the American Medical Directors Association

Defining Sarcopenia in Terms of Incident Adverse Outcomes

(2015) Jean Woo et al.   Journal of the American Medical Directors Association

There Are No Nonresponders to Resistance-Type Exercise Training in Older Men and Women

(2015) Tyler A. Churchward-Venne et al.   Journal of the American Medical Directors Association

Effects of a Vitamin D and Leucine-Enriched Whey Protein Nutritional Supplement on Measures of Sarcopenia in Older Adults, the PROVIDE Study: A Randomized, Double-Blind, Placebo-Controlled Trial

(2015) Jürgen M. Bauer et al.   Journal of the American Medical Directors Association

Functional and splicing defect analysis of 23 ACVRL1 mutations in a cohort of patients affected by Hereditary Hemorrhagic Telangiectasia

(2015) Ferdos Alaa el Din et al.   PLoS One

The Look AHEAD Trial: Implications for Lifestyle Intervention in Type 2 Diabetes Mellitus

(2015) Gareth R. Dutton et al.   PROGRESS IN CARDIOVASCULAR DISEASES

Personalized Preventive Medicine: Genetics and the Response to Regular Exercise in Preventive Interventions

(2015) Claude Bouchard et al.   PROGRESS IN CARDIOVASCULAR DISEASES

In vivo gene editing in dystrophic mouse muscle and muscle stem cells

(2015) M. Tabebordbar et al.   SCIENCE

Detecting Skeletal Microvascular Flow Abnormalities in Diabetes

(2015) Thomas R. Porter   JACC-Cardiovascular Imaging

Ethical guidelines for publishing in the Journal of Cachexia, Sarcopenia and Muscle: update 2015

(2015) Stephan von Haehling et al.   Journal of Cachexia Sarcopenia and Muscle

Rapid screening for sarcopenia

(2015) John E. Morley et al.   Journal of Cachexia Sarcopenia and Muscle

SARC-F: a symptom score to predict persons with sarcopenia at risk for poor functional outcomes

(2015) Theodore K. Malmstrom et al.   Journal of Cachexia Sarcopenia and Muscle

Pathophysiology of anorexia in the cancer cachexia syndrome

(2015) Chukwuemeka Charles Ezeoke et al.   Journal of Cachexia Sarcopenia and Muscle

Myostatin antibody (LY2495655) in older weak fallers: a proof-of-concept, randomised, phase 2 trial

(2015) Clemens Becker et al.   Lancet Diabetes & Endocrinology

Precise Correction of the Dystrophin Gene in Duchenne Muscular Dystrophy Patient Induced Pluripotent Stem Cells by TALEN and CRISPR-Cas9

(2015) Hongmei Lisa Li et al.   Stem Cell Reports

Sarcopenia in Asia: Consensus Report of the Asian Working Group for Sarcopenia

(2014) Liang-Kung Chen et al.   Journal of the American Medical Directors Association

Motoneuron Loss Is Associated With Sarcopenia

(2014) Michael Drey et al.   Journal of the American Medical Directors Association

Sarcopenia: There Is a Need for Some Steps Forward

(2014) Jean-Pierre Michel   Journal of the American Medical Directors Association

Validating the SARC-F: A Suitable Community Screening Tool for Sarcopenia?

(2014) Jean Woo et al.   Journal of the American Medical Directors Association

ICU-Acquired Weakness and Recovery from Critical Illness

(2014) John P. Kress et al.   NEW ENGLAND JOURNAL OF MEDICINE

Beneficial Effects of Testosterone Therapy on Functional Capacity, Cardiovascular Parameters, and Quality of Life in Patients with Congestive Heart Failure

(2014) Ahmad Mirdamadi et al.   Biomed Research International

Muscle wasting disease: a proposal for a new disease classification

(2014) Stefan D. Anker et al.   Journal of Cachexia Sarcopenia and Muscle

Assessing skeletal muscle mass: historical overview and state of the art

(2014) Steven B. Heymsfield et al.   Journal of Cachexia Sarcopenia and Muscle

Myostatin/activin pathway antagonism: Molecular basis and therapeutic potential

(2013) H.Q. Han et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Mitochondrial dysfunction and sarcopenia of aging: From signaling pathways to clinical trials

(2013) Emanuele Marzetti et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

A pilot study of the SARC-F scale on screening sarcopenia and physical disability in the Chinese older people

(2013) L. Cao et al.   Journal of Nutrition Health & Aging

Evidence-Based Recommendations for Optimal Dietary Protein Intake in Older People: A Position Paper From the PROT-AGE Study Group

(2013) Jürgen Bauer et al.   Journal of the American Medical Directors Association

SARC-F: A Simple Questionnaire to Rapidly Diagnose Sarcopenia

(2013) Theodore K. Malmstrom et al.   Journal of the American Medical Directors Association

An ex vivo gene therapy approach to treat muscular dystrophy using inducible pluripotent stem cells

(2013) Antonio Filareto et al.   Nature Communications

Testosterone therapy during exercise rehabilitation in male patients with chronic heart failure who have low testosterone status: A double-blind randomized controlled feasibility study

(2012) Martin Stout et al.   AMERICAN HEART JOURNAL

Testosterone Supplementation in Heart Failure

(2012) Mustafa Toma et al.   Circulation-Heart Failure

Sarcopenia in the elderly

(2012) J. E. Morley   FAMILY PRACTICE

Myostatin is associated with age-related human muscle stem cell dysfunction

(2012) Bryon R. McKay et al.   FASEB JOURNAL

Muscle atrophy is not always sarcopenia

(2012) Russell T. Hepple   JOURNAL OF APPLIED PHYSIOLOGY

A single ascending-dose study of muscle regulator ace-031 in healthy volunteers

(2012) Kenneth M. Attie et al.   MUSCLE & NERVE

Sarcopenia Predicts Early Dose-Limiting Toxicities and Pharmacokinetics of Sorafenib in Patients with Hepatocellular Carcinoma

(2012) Olivier Mir et al.   PLoS One

Implementing Early Mobilization Interventions in Mechanically Ventilated Patients in the ICU

(2011) William D. Schweickert et al.   CHEST

Sarcopenia With Limited Mobility: An International Consensus

(2011) John E. Morley et al.   Journal of the American Medical Directors Association

Current Status of Pharmaceutical and Genetic Therapeutic Approaches to Treat DMD

(2011) Christophe Pichavant et al.   MOLECULAR THERAPY

Serum myostatin levels and skeletal muscle wasting in chronic obstructive pulmonary disease

(2011) Chun-Rong Ju et al.   RESPIRATORY MEDICINE

Testosterone and heart failure

(2011) Chris J Malkin et al.   Current Opinion in Endocrinology Diabetes and Obesity

Myopenia-a new universal term for muscle wasting

(2011) Kenneth Fearon et al.   Journal of Cachexia Sarcopenia and Muscle

Late-Life Onset Hypogonadism: A Review

(2010) Nazem Bassil et al.   CLINICS IN GERIATRIC MEDICINE

Splice Modification to Restore Functional Dystrophin Synthesis in Duchenne Muscular Dystrophy

(2010) Steve. Wilton et al.   CURRENT PHARMACEUTICAL DESIGN

Testosterone modulates gene expression pathways regulating nutrient accumulation, glucose metabolism and protein turnover in mouse skeletal muscle

(2010) M. T. Haren et al.   INTERNATIONAL JOURNAL OF ANDROLOGY

Association of Skeletal Muscle Wasting With Treatment With Sorafenib in Patients With Advanced Renal Cell Carcinoma: Results From a Placebo-Controlled Study

(2010) Sami Antoun et al.   JOURNAL OF CLINICAL ONCOLOGY

Testosterone Therapy in Women With Chronic Heart Failure

(2010) Ferdinando Iellamo et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Consensus on Cachexia Definitions

(2010) Josep M. Argilés et al.   Journal of the American Medical Directors Association

Difficulties with physical function associated with obesity, sarcopenia, and sarcopenic-obesity in community-dwelling elderly women: the EPIDOS (EPIDemiologie de l’OSteoporose) Study

(2009) Yves Rolland et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

Theoretic applicability of antisense-mediated exon skipping for Duchenne muscular dystrophy mutations

(2009) Annemieke Aartsma-Rus et al.   HUMAN MUTATION

Effect of Long-Acting Testosterone Treatment on Functional Exercise Capacity, Skeletal Muscle Performance, Insulin Resistance, and Baroreflex Sensitivity in Elderly Patients With Chronic Heart Failure

(2009) Giuseppe Caminiti et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Vitamin D Redux

(2009) John E. Morley   Journal of the American Medical Directors Association

Cachexia: A new definition

(2008) William J. Evans et al.   CLINICAL NUTRITION

Sarcopenia: Its assessment, etiology, pathogenesis, consequences and future perspectives

(2008) Y. Rolland et al.   Journal of Nutrition Health & Aging