Overexpression of Chromosome 21 miRNAs May Affect Mitochondrial Function in the Hearts of Down Syndrome Fetuses

STarMirDB: A database of microRNA binding sites

(2016) William Rennie et al.   RNA Biology

Chromosome 21-derived hsa-miR-155-5p regulates mitochondrial biogenesis by targeting Mitochondrial Transcription Factor A (TFAM)

(2015) Adolfo Quiñones-Lombraña et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Genome-wide miR-155 and miR-802 target gene identification in the hippocampus of Ts65Dn Down syndrome mouse model by miRNA sponges

(2015) Xavier Bofill-De Ros et al.   BMC GENOMICS

miRTarBase 2016: updates to the experimentally validated miRNA-target interactions database

(2015) Chih-Hung Chou et al.   NUCLEIC ACIDS RESEARCH

Loss of MicroRNA-155 Protects the Heart From Pathological Cardiac Hypertrophy

(2014) Hee Young Seok et al.   CIRCULATION RESEARCH

NRIP1/RIP140 siRNA-mediated attenuation counteracts mitochondrial dysfunction in Down syndrome

(2014) Antonella Izzo et al.   HUMAN MOLECULAR GENETICS

Global Analyses of the Effect of Different Cellular Contexts on MicroRNA Targeting

(2014) Jin-Wu Nam et al.   MOLECULAR CELL

miRDB: an online resource for microRNA target prediction and functional annotations

(2014) Nathan Wong et al.   NUCLEIC ACIDS RESEARCH

Mapping the Human miRNA Interactome by CLASH Reveals Frequent Noncanonical Binding

(2013) Aleksandra Helwak et al.   CELL

Engineered chromosome-based genetic mapping establishes a 3.7 Mb critical genomic region for Down syndrome-associated heart defects in mice

(2013) Chunhong Liu et al.   HUMAN GENETICS

WEB-based GEne SeT AnaLysis Toolkit (WebGestalt): update 2013

(2013) Jing Wang et al.   NUCLEIC ACIDS RESEARCH

Cardiomyogenesis is controlled by the miR-99a/let-7c cluster and epigenetic modifications

(2013) Antonietta Coppola et al.   Stem Cell Research

Functional microRNA targets in protein coding sequences

(2012) Martin Reczko et al.   BIOINFORMATICS

Chronic pro-oxidative state and mitochondrial dysfunctions are more pronounced in fibroblasts from Down syndrome foeti with congenital heart defects

(2012) C. Piccoli et al.   HUMAN MOLECULAR GENETICS

Fiji: an open-source platform for biological-image analysis

(2012) Johannes Schindelin et al.   NATURE METHODS

Mouse Models for Down Syndrome-Associated Developmental Cognitive Disabilities

(2011) Chunhong Liu et al.   DEVELOPMENTAL NEUROSCIENCE

Trisomy-21 gene dosage over-expression of miRNAs results in the haploinsufficiency of specific target proteins

(2011) Terry S. Elton et al.   RNA Biology

Comprehensive modeling of microRNA targets predicts functional non-conserved and non-canonical sites

(2010) Doron Betel et al.   GENOME BIOLOGY

TargetMiner: microRNA target prediction with systematic identification of tissue-specific negative examples

(2009) Sanghamitra Bandyopadhyay et al.   BIOINFORMATICS

Insights into the manifestations, outcomes, and mechanisms of leukemogenesis in Down syndrome

(2009) S. Malinge et al.   BLOOD

MicroRNAs: Target Recognition and Regulatory Functions

(2009) David P. Bartel   CELL

Argonaute HITS-CLIP decodes microRNA–mRNA interaction maps

(2009) Sung Wook Chi et al.   NATURE

Mapping identifiers for the integration of genomic datasets with the R/Bioconductor package biomaRt

(2009) Steffen Durinck et al.   Nature Protocols

MITOCHIP assessment of differential gene expression in the skeletal muscle of Ant1 knockout mice: Coordinate regulation of OXPHOS, antioxidant, and apoptotic genes

(2008) Vaidya Subramaniam et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

let-7 regulates Dicer expression and constitutes a negative feedback loop

(2008) Shogo Tokumaru et al.   CARCINOGENESIS

Sustained expression of microRNA-155 in hematopoietic stem cells causes a myeloproliferative disorder

(2008) Ryan M. O'Connell et al.   JOURNAL OF EXPERIMENTAL MEDICINE