NRIP1/RIP140 siRNA-mediated attenuation counteracts mitochondrial dysfunction in Down syndrome

The Therapeutic Potential of Nuclear Receptor Modulators for Treatment of Metabolic Disorders: PPARγ, RORs, and Rev-erbs

(2014) David P. Marciano et al.   Cell Metabolism

Adaptive Downregulation of Mitochondrial Function in Down Syndrome

(2013) Pablo Helguera et al.   Cell Metabolism

Prospects for Improving Brain Function in Individuals with Down Syndrome

(2013) Alberto C. S. Costa et al.   CNS DRUGS

Subcellular calcium measurements in mammalian cells using jellyfish photoprotein aequorin-based probes

(2013) Massimo Bonora et al.   Nature Protocols

WEB-based GEne SeT AnaLysis Toolkit (WebGestalt): update 2013

(2013) Jing Wang et al.   NUCLEIC ACIDS RESEARCH

Distinct functions for RIP140 in development, inflammation, and metabolism

(2013) Jaya Nautiyal et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Chronic pro-oxidative state and mitochondrial dysfunctions are more pronounced in fibroblasts from Down syndrome foeti with congenital heart defects

(2012) C. Piccoli et al.   HUMAN MOLECULAR GENETICS

Roles of transcriptional corepressor RIP140 and coactivator PGC-1α in energy state of chronically infarcted rat hearts and mitochondrial function of cardiomyocytes

(2012) Yanfang Chen et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Bezafibrate can be a new treatment option for mitochondrial fatty acid oxidation disorders: Evaluation by in vitro probe acylcarnitine assay

(2012) Seiji Yamaguchi et al.   MOLECULAR GENETICS AND METABOLISM

Absence of RIP140 Reveals a Pathway Regulating glut4-Dependent Glucose Uptake in Oxidative Skeletal Muscle through UCP1-Mediated Activation of AMPK

(2012) Asmaà Fritah et al.   PLoS One

ATP synthesis and storage

(2012) Massimo Bonora et al.   Purinergic Signalling

Transcriptional integration of mitochondrial biogenesis

(2012) Richard C. Scarpulla et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Deficit of complex I activity in human skin fibroblasts with chromosome 21 trisomy and overproduction of reactive oxygen species by mitochondria: involvement of the cAMP/PKA signalling pathway

(2011) Daniela Valenti et al.   BIOCHEMICAL JOURNAL

Meta-analysis of heterogeneous Down Syndrome data reveals consistent genome-wide dosage effects related to neurological processes

(2011) Mireia Vilardell et al.   BMC GENOMICS

Calcium signaling around Mitochondria Associated Membranes (MAMs)

(2011) Simone Patergnani et al.   Cell Communication and Signaling

CDH16/Ksp-Cadherin Is Expressed in the Developing Thyroid Gland and Is Strongly Down-Regulated in Thyroid Carcinomas

(2011) Gaetano Calì et al.   ENDOCRINOLOGY

Pharmacologic activation of mitochondrial biogenesis exerts widespread beneficial effects in a transgenic mouse model of Huntington's disease

(2011) Ashu Johri et al.   HUMAN MOLECULAR GENETICS

The transcriptional coactivators, PGC-1α and β, cooperate to maintain cardiac mitochondrial function during the early stages of insulin resistance

(2011) Riddhi Mitra et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

The metabolic coregulator RIP140: an update

(2010) Asmaà Fritah et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Impairment of F1F0-ATPase, adenine nucleotide translocator and adenylate kinase causes mitochondrial energy deficit in human skin fibroblasts with chromosome 21 trisomy

(2010) Daniela Valenti et al.   BIOCHEMICAL JOURNAL

Metabolic control of mitochondrial biogenesis through the PGC-1 family regulatory network

(2010) Richard C. Scarpulla   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Elevated expression of the metabolic regulator receptor-interacting protein 140 results in cardiac hypertrophy and impaired cardiac function

(2010) Asmaà Fritah et al.   CARDIOVASCULAR RESEARCH

Pioglitazone attenuates mitochondrial dysfunction, cognitive impairment, cortical tissue loss, and inflammation following traumatic brain injury

(2010) Andrew Sauerbeck et al.   EXPERIMENTAL NEUROLOGY

A mouse embryonic stem cell bank for inducible overexpression of human chromosome 21 genes

(2010) Rossella De Cegli et al.   GENOME BIOLOGY

SUMOylation Attenuates the Function of PGC-1α

(2009) Miia M. Rytinki et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Efficacy of PPAR-γ agonist pioglitazone in mild Alzheimer disease

(2009) Tomohiko Sato et al.   NEUROBIOLOGY OF AGING

Rosiglitazone reverses memory decline and hippocampal glucocorticoid receptor down-regulation in an Alzheimer’s disease mouse model

(2008) Luis Escribano et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

SUMOylation Modulates the Transcription Repressor Function of RIP140

(2008) Miia M. Rytinki et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Activation of Peroxisome Proliferator-Activated Receptor Pathway Stimulates the Mitochondrial Respiratory Chain and Can Correct Deficiencies in Patients’ Cells Lacking Its Components

(2008) Jean Bastin et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Complete Rescue of Cerebrovascular Function in Aged Alzheimer's Disease Transgenic Mice by Antioxidants and Pioglitazone, a Peroxisome Proliferator-Activated Receptor   Agonist

(2008) N. Nicolakakis et al.   JOURNAL OF NEUROSCIENCE

A Functional Interaction between RIP140 and PGC-1  Regulates the Expression of the Lipid Droplet Protein CIDEA

(2008) M. Hallberg et al.   MOLECULAR AND CELLULAR BIOLOGY