The Anti-helminthic Compound Mebendazole Has Multiple Antifungal Effects against Cryptococcus neoformans

The clinically approved antiviral drug sofosbuvir inhibits Zika virus replication

(2017) Carolina Q. Sacramento et al.   Scientific Reports

Antimicrobial Activities of 1-H-Benzimidazole-based Molecules

(2016) Zeynep Ates-Alagoz   CURRENT TOPICS IN MEDICINAL CHEMISTRY

Efficacy of adjunctive sertraline for the treatment of HIV-associated cryptococcal meningitis: an open-label dose-ranging study

(2016) Joshua Rhein et al.   LANCET INFECTIOUS DISEASES

Can you teach old drugs new tricks?

(2016) Nicola Nosengo   NATURE

Identification of small-molecule inhibitors of Zika virus infection and induced neural cell death via a drug repurposing screen

(2016) Miao Xu et al.   NATURE MEDICINE

Funding and Innovation in Diseases of Neglected Populations: The Paradox of Cryptococcal Meningitis

(2016) Marcio L. Rodrigues   PLoS Neglected Tropical Diseases

Virulence of Cryptococcus sp. Biofilms In Vitro and In Vivo using Galleria mellonella as an Alternative Model

(2016) Tatiane Benaducci et al.   Frontiers in Microbiology

Fungal colonization of the brain: anatomopathological aspects of neurological cryptococcosis

(2015) ANA CAROLINE COLOMBO et al.   ANAIS DA ACADEMIA BRASILEIRA DE CIENCIAS

Brain Penetration and Efficacy of Different Mebendazole Polymorphs in a Mouse Brain Tumor Model

(2015) R.-Y. Bai et al.   CLINICAL CANCER RESEARCH

Structure activity relationship (SAR) study of benzimidazole scaffold for different biological activities: A mini-review

(2015) Geeta Yadav et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Toward improved anti-cryptococcal drugs: Novel molecules and repurposed drugs

(2015) Damian J. Krysan   FUNGAL GENETICS AND BIOLOGY

Introduction of an antifungal stewardship programme targeting high-cost antifungals at a tertiary hospital in Cambridge, England

(2015) C. Micallef et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

The Pfam protein families database: towards a more sustainable future

(2015) Robert D. Finn et al.   NUCLEIC ACIDS RESEARCH

Identification of a New Class of Antifungals Targeting the Synthesis of Fungal Sphingolipids

(2015) Visesato Mor et al.   mBio

Pathogenic diversity amongst serotype C VGIII and VGIV Cryptococcus gattii isolates

(2015) Jéssica Rodrigues et al.   Scientific Reports

Role of Flippases, Scramblases and Transfer Proteins in Phosphatidylserine Subcellular Distribution

(2014) Hannah M. Hankins et al.   TRAFFIC

Cryptococcus neoformans and Cryptococcus gattii, the Etiologic Agents of Cryptococcosis

(2014) K. J. Kwon-Chung et al.   Cold Spring Harbor Perspectives in Medicine

Cost analysis of voriconazole versus liposomal amphotericin B for primary therapy of invasive aspergillosis among patients with haematological disorders in Germany and Spain

(2014) Helmut Ostermann et al.   BMC Pharmacology & Toxicology

Role of the Apt1 Protein in Polysaccharide Secretion by Cryptococcus neoformans

(2013) Juliana Rizzo et al.   EUKARYOTIC CELL

The Antidepressant Sertraline Provides a Promising Therapeutic Option for Neurotropic Cryptococcal Infections

(2012) Bing Zhai et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

The therapeutic journey of benzimidazoles: A review

(2012) Yogita Bansal et al.   BIOORGANIC & MEDICINAL CHEMISTRY

EUCAST technical note on the EUCAST definitive document EDef 7.2: method for the determination of broth dilution minimum inhibitory concentrations of antifungal agents for yeasts EDef 7.2 (EUCAST-AFST)*

(2012) Maiken C. Arendrup et al.   CLINICAL MICROBIOLOGY AND INFECTION

Trends in Antifungal Drug Susceptibility of Cryptococcus neoformans Isolates Obtained through Population-Based Surveillance in South Africa in 2002-2003 and 2007-2008

(2011) Nelesh P. Govender et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Deconstructing the Drug Development Process: The New Face of Innovation

(2010) K I Kaitin   CLINICAL PHARMACOLOGY & THERAPEUTICS

Pharmaceutical Innovation in the 21st Century: New Drug Approvals in the First Decade, 2000–2009

(2010) K I Kaitin et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

Cryptococcal Interactions with the Host Immune System

(2010) Kerstin Voelz et al.   EUKARYOTIC CELL

Estimation of the current global burden of cryptococcal meningitis among persons living with HIV/AIDS

(2009) Benjamin J Park et al.   AIDS

Treatment of cryptococcal meningitis in resource limited settings

(2009) Derek J Sloan et al.   CURRENT OPINION IN INFECTIOUS DISEASES

A Putative P-Type ATPase, Apt1, Is Involved in Stress Tolerance and Virulence inCryptococcus neoformans

(2009) Guanggan Hu et al.   EUKARYOTIC CELL

Estimation of the cost of large-scale school deworming programmes with benzimidazoles

(2009) A. Montresor et al.   TRANSACTIONS OF THE ROYAL SOCIETY OF TROPICAL MEDICINE AND HYGIENE

EUCAST Definitive Document EDef 7.1: method for the determination of broth dilution MICs of antifungal agents for fermentative yeasts

(2008) J.L. Rodriguez-Tudela et al.   CLINICAL MICROBIOLOGY AND INFECTION