The Promise of Systems Biology Approaches for Revealing Host Pathogen Interactions in Malaria
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Title
The Promise of Systems Biology Approaches for Revealing Host Pathogen Interactions in Malaria
Authors
Keywords
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Journal
Frontiers in Microbiology
Volume 8, Issue -, Pages -
Publisher
Frontiers Media SA
Online
2017-11-16
DOI
10.3389/fmicb.2017.02183
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Note: Only part of the references are listed.- Single-cell RNA sequencing reveals a signature of sexual commitment in malaria parasites
- (2017) Asaf Poran et al. NATURE
- Antimalarial drug resistance: linking Plasmodium falciparum parasite biology to the clinic
- (2017) Benjamin Blasco et al. NATURE MEDICINE
- Plasmodium bergheiEXP-1 interacts with host Apolipoprotein H duringPlasmodiumliver-stage development
- (2017) Cláudia Sá e Cunha et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Manipulation of the Host Cell Membrane during Plasmodium Liver Stage Egress
- (2017) Paul-Christian Burda et al. mBio
- Identifying host regulators and inhibitors of liver stage malaria infection using kinase activity profiles
- (2017) Nadia Arang et al. Nature Communications
- Cell Traversal Activity Is Important for Plasmodium falciparum Liver Infection in Humanized Mice
- (2017) Annie S.P. Yang et al. Cell Reports
- Malaria Parasite Liver Infection and Exoerythrocytic Biology
- (2017) Ashley M. Vaughan et al. Cold Spring Harbor Perspectives in Medicine
- Plasmodium P36 determines host cell receptor usage during sporozoite invasion
- (2017) Giulia Manzoni et al. eLife
- Identification of GAPDH on the surface of Plasmodium sporozoites as a new candidate for targeting malaria liver invasion
- (2016) Sung-Jae Cha et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Progress in imaging methods: insights gained into Plasmodium biology
- (2016) Mariana De Niz et al. NATURE REVIEWS MICROBIOLOGY
- Integrated transcriptomic and proteomic analyses ofP. falciparumgametocytes: molecular insight into sex-specific processes and translational repression
- (2016) Edwin Lasonder et al. NUCLEIC ACIDS RESEARCH
- A redesigned CRISPR/Cas9 system for marker-free genome editing in Plasmodium falciparum
- (2016) Junnan Lu et al. Parasites & Vectors
- Host AMPK Is a Modulator of Plasmodium Liver Infection
- (2016) Margarida T. Grilo Ruivo et al. Cell Reports
- Translational Control of UIS4 Protein of the Host-Parasite Interface Is Mediated by the RNA Binding Protein Puf2 in Plasmodium berghei Sporozoites
- (2016) Patrícia A. G. C. Silva et al. PLoS One
- A Human Interactome in Three Quantitative Dimensions Organized by Stoichiometries and Abundances
- (2015) Marco Y. Hein et al. CELL
- The BioPlex Network: A Systematic Exploration of the Human Interactome
- (2015) Edward L. Huttlin et al. CELL
- Selection and refinement: the malaria parasite's infection and exploitation of host hepatocytes
- (2015) Alexis Kaushansky et al. CURRENT OPINION IN MICROBIOLOGY
- Parasite-induced ER stress response in hepatocytes facilitates Plasmodium liver stage infection
- (2015) P. Inacio et al. EMBO REPORTS
- Host ER stress during malaria parasite infection
- (2015) A. Kaushansky et al. EMBO REPORTS
- Host-based Prophylaxis Successfully Targets Liver Stage Malaria Parasites
- (2015) Alyse N Douglass et al. MOLECULAR THERAPY
- Genetic Diversity and Protective Efficacy of the RTS,S/AS01 Malaria Vaccine
- (2015) Daniel E. Neafsey et al. NEW ENGLAND JOURNAL OF MEDICINE
- Heterologous Protection against Malaria after Immunization with Plasmodium falciparum Sporozoites
- (2015) Remko Schats et al. PLoS One
- Malaria parasites target the hepatocyte receptor EphA2 for successful host infection
- (2015) A. Kaushansky et al. SCIENCE
- Host Cell Phosphatidylcholine Is a Key Mediator of Malaria Parasite Survival during Liver Stage Infection
- (2014) Maurice A. Itoe et al. Cell Host & Microbe
- A Plasmodium falciparum Histone Deacetylase Regulates Antigenic Variation and Gametocyte Conversion
- (2014) Bradley I. Coleman et al. Cell Host & Microbe
- Two Plasmodium 6-Cys family-related proteins have distinct and critical roles in liver-stage development
- (2014) Takeshi Annoura et al. FASEB JOURNAL
- Post-transcriptional silencing ofUIS4inPlasmodium bergheisporozoites is important for host switch
- (2014) Olivier Silvie et al. MOLECULAR MICROBIOLOGY
- A cascade of DNA-binding proteins for sexual commitment and development in Plasmodium
- (2014) Abhinav Sinha et al. NATURE
- A transcriptional switch underlies commitment to sexual development in malaria parasites
- (2014) Björn F. C. Kafsack et al. NATURE
- Genome editing in the human malaria parasite Plasmodium falciparum using the CRISPR-Cas9 system
- (2014) Mehdi Ghorbal et al. NATURE BIOTECHNOLOGY
- A multiscale statistical mechanical framework integrates biophysical and genomic data to assemble cancer networks
- (2014) Mohammed AlQuraishi et al. NATURE GENETICS
- Efficient CRISPR-Cas9–mediated genome editing in Plasmodium falciparum
- (2014) Jeffrey C Wagner et al. NATURE METHODS
- Exploiting polypharmacology for drug target deconvolution
- (2014) Taranjit Singh Gujral et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Plasmodium falciparum transmission stages accumulate in the human bone marrow
- (2014) R. Joice et al. Science Translational Medicine
- The Spatiotemporal Dynamics and Membranous Features of thePlasmodiumLiver Stage Tubovesicular Network
- (2014) Josephine Grützke et al. TRAFFIC
- Interferon-Mediated Innate Immune Responses against Malaria Parasite Liver Stages
- (2014) Jessica L. Miller et al. Cell Reports
- Perturbations ofPlasmodium Puf2 expression and RNA-seq of Puf2-deficient sporozoites reveal a critical role in maintaining RNA homeostasis and parasite transmissibility
- (2013) Scott E. Lindner et al. CELLULAR MICROBIOLOGY
- A Key Role forPlasmodiumSubtilisin-like SUB1 Protease in Egress of Malaria Parasites from Host Hepatocytes
- (2013) Lina Tawk et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Role of host cell traversal by the malaria sporozoite during liver infection
- (2013) Joana Tavares et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Host-cell sensors for Plasmodium activate innate immunity against liver-stage infection
- (2013) Peter Liehl et al. NATURE MEDICINE
- The CRAPome: a contaminant repository for affinity purification–mass spectrometry data
- (2013) Dattatreya Mellacheruvu et al. NATURE METHODS
- Molecular mechanisms of system responses to novel stimuli are predictable from public data
- (2013) Samuel A. Danziger et al. NUCLEIC ACIDS RESEARCH
- Protection against malaria after immunization by chloroquine prophylaxis and sporozoites is mediated by preerythrocytic immunity
- (2013) E. M. Bijker et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- RNA-Guided Human Genome Engineering via Cas9
- (2013) P. Mali et al. SCIENCE
- Multiplex Genome Engineering Using CRISPR/Cas Systems
- (2013) L. Cong et al. SCIENCE
- Malaria parasite liver stages render host hepatocytes susceptible to mitochondria-initiated apoptosis
- (2013) A Kaushansky et al. Cell Death & Disease
- Suppression of Host p53 Is Critical for Plasmodium Liver-Stage Infection
- (2013) Alexis Kaushansky et al. Cell Reports
- Complete Plasmodium falciparum liver-stage development in liver-chimeric mice
- (2012) Ashley M. Vaughan et al. JOURNAL OF CLINICAL INVESTIGATION
- Liver-specific protein 2: a Plasmodium protein exported to the hepatocyte cytoplasm and required for merozoite formation
- (2012) Yuki Orito et al. MOLECULAR MICROBIOLOGY
- Plasmodium berghei Δp52&p36 Parasites Develop Independent of a Parasitophorous Vacuole Membrane in Huh-7 Liver Cells
- (2012) Ivo H. J. Ploemen et al. PLoS One
- Evidence from NMR interaction studies challenges the hypothesis of direct lipid transfer from L-FABP to malaria sporozoite protein UIS3
- (2012) Filippo Favretto et al. PROTEIN SCIENCE
- Resolving protein interactions and complexes by affinity purification followed by label-based quantitative mass spectrometry
- (2012) Laura Trinkle-Mulcahy PROTEOMICS
- The Host Endocytic Pathway is Essential for Plasmodium berghei Late Liver Stage Development
- (2012) Mafalda Lopes da Silva et al. TRAFFIC
- Scavenger receptor class B type I: a multifunctional receptor
- (2011) Giuseppe Valacchi et al. Annals of the New York Academy of Sciences
- Use of a Selective Inhibitor To Define the Chemotherapeutic Potential of the Plasmodial Hexose Transporter in Different Stages of the Parasite's Life Cycle
- (2011) Ksenija Slavic et al. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
- Intravital Imaging
- (2011) Mikael J. Pittet et al. CELL
- The malaria circumsporozoite protein has two functional domains, each with distinct roles as sporozoites journey from mosquito to mammalian host
- (2011) Alida Coppi et al. JOURNAL OF EXPERIMENTAL MEDICINE
- The Puf-Family RNA-Binding Protein Puf2 Controls Sporozoite Conversion to Liver Stages in the Malaria Parasite
- (2011) Katja Müller et al. PLoS One
- Transition of Plasmodium Sporozoites into Liver Stage-Like Forms Is Regulated by the RNA Binding Protein Pumilio
- (2011) Carina S. S. Gomes-Santos et al. PLoS Pathogens
- Hostile Takeover by Plasmodium: Reorganization of Parasite and Host Cell Membranes during Liver Stage Egress
- (2011) Stefanie Graewe et al. PLoS Pathogens
- A constitutive pan-hexose permease for the Plasmodium life cycle and transgenic models for screening of antimalarial sugar analogs
- (2010) Martin Blume et al. FASEB JOURNAL
- ThePlasmodiumeukaryotic initiation factor-2α kinase IK2 controls the latency of sporozoites in the mosquito salivary glands
- (2010) Min Zhang et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Visualization of omics data for systems biology
- (2010) Nils Gehlenborg et al. NATURE METHODS
- Host cell transcriptional profiling during malaria liver stage infection reveals a coordinated and sequential set of biological events
- (2009) Sónia S Albuquerque et al. BMC GENOMICS
- Clonal Conditional Mutagenesis in Malaria Parasites
- (2009) Audrey Combe et al. Cell Host & Microbe
- LISP1 is important for the egress ofPlasmodium bergheiparasites from liver cells
- (2009) Tomoko Ishino et al. CELLULAR MICROBIOLOGY
- Highly efficient subcloning of rodent malaria parasites by injection of single merosomes or detached cells
- (2009) Rebecca R Stanway et al. Nature Protocols
- Host Scavenger Receptor SR-BI Plays a Dual Role in the Establishment of Malaria Parasite Liver Infection
- (2008) Cristina D. Rodrigues et al. Cell Host & Microbe
- Scavenger Receptor BI Boosts Hepatocyte Permissiveness to Plasmodium Infection
- (2008) Samir Yalaoui et al. Cell Host & Microbe
- The Plasmodium TRAP/MIC2 family member, TRAP-Like Protein (TLP), is involved in tissue traversal by sporozoites
- (2008) Cristina K. Moreira et al. CELLULAR MICROBIOLOGY
- Type II fatty acid synthesis is essential only for malaria parasite late liver stage development
- (2008) Ashley M. Vaughan et al. CELLULAR MICROBIOLOGY
- Identifying specific protein interaction partners using quantitative mass spectrometry and bead proteomes
- (2008) Laura Trinkle-Mulcahy et al. JOURNAL OF CELL BIOLOGY
- Distinct Malaria Parasite Sporozoites Reveal Transcriptional Changes That Cause Differential Tissue Infection Competence in the Mosquito Vector and Mammalian Host
- (2008) S. A. Mikolajczak et al. MOLECULAR AND CELLULAR BIOLOGY
- Correlative light-electron microscopy (CLEM) combining live-cell imaging and immunolabeling of ultrathin cryosections
- (2008) Carolien van Rijnsoever et al. NATURE METHODS
- A combined transcriptome and proteome survey of malaria parasite liver stages
- (2008) A. S. Tarun et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- No TRAP, no invasion
- (2008) Belinda J. Morahan et al. TRENDS IN PARASITOLOGY
- Hepatocyte Permissiveness to Plasmodium Infection Is Conveyed by a Short and Structurally Conserved Region of the CD81 Large Extracellular Domain
- (2008) Samir Yalaoui et al. PLoS Pathogens
- Kinome-Wide RNAi Screen Implicates at Least 5 Host Hepatocyte Kinases in Plasmodium Sporozoite Infection
- (2008) Miguel Prudêncio et al. PLoS Pathogens
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