A Vibrio vulnificus VvpM Induces IL-1β Production Coupled with Necrotic Macrophage Death via Distinct Spatial Targeting by ANXA2

Annexins – insights from knockout mice

(2016) Thomas Grewal et al.   BIOLOGICAL CHEMISTRY

VvpE mediates the intestinal colonization of Vibrio vulnificus by the disruption of tight junctions

(2016) Sei-Jung Lee et al.   INTERNATIONAL JOURNAL OF MEDICAL MICROBIOLOGY

Regulatory Characteristics ofVibrio vulnificus gbpAGene Encoding a Mucin-binding Protein Essential for Pathogenesis

(2016) Kyung Ku Jang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Annexin A2 Modulates ROS and Impacts Inflammatory Response via IL-17 Signaling in Polymicrobial Sepsis Mice

(2016) Sisi He et al.   PLoS Pathogens

Vibrio vulnificus VvhA induces autophagy-related cell death through the lipid raft-dependent c-Src/NOX signaling pathway

(2016) Eun Ju Song et al.   Scientific Reports

Vibrio vulnificusVvpE Stimulates IL-1β Production by the Hypomethylation of the IL-1β Promoter and NF-κB Activation via Lipid Raft–Dependent ANXA2 Recruitment and Reactive Oxygen Species Signaling in Intestinal Epithelial Cells

(2015) Sei-Jung Lee et al.   JOURNAL OF IMMUNOLOGY

VvpM Induces Human Cell Death via Multifarious Modes Including Necroptosis and Autophagy

(2015) Mi-Ae Lee et al.   JOURNAL OF MICROBIOLOGY AND BIOTECHNOLOGY

Inflammasomes: mechanism of action, role in disease and therapeutics

(2015) Haitao Guo et al.   NATURE MEDICINE

Mitophagy confers resistance to siderophore-mediated killing byPseudomonas aeruginosa

(2015) Natalia V. Kirienko et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Vibrio vulnificus VvpE inhibits mucin 2 expression by hypermethylation via lipid raft-mediated ROS signaling in intestinal epithelial cells

(2015) S-J Lee et al.   Cell Death & Disease

Vibrio vulnificus VvhA induces NF-κB-dependent mitochondrial cell death via lipid raft-mediated ROS production in intestinal epithelial cells

(2015) S-J Lee et al.   Cell Death & Disease

Erratum: Corrigendum: Annexin A2 promotes phagophore assembly by enhancing Atg16+ vesicle biogenesis and homotypic fusion

(2015) Kateryna Morozova et al.   Nature Communications

Site-specific processing of Ras and Rap1 Switch I by a MARTX toxin effector domain

(2015) Irena Antic et al.   Nature Communications

VvpM, an extracellular metalloprotease of Vibrio vulnificus, induces apoptotic death of human cells

(2014) Mi-Ae Lee et al.   JOURNAL OF MICROBIOLOGY

Melatonin enhances the human mesenchymal stem cells motility via melatonin receptor 2 coupling with Gαq in skin wound healing

(2014) Sei-Jung Lee et al.   JOURNAL OF PINEAL RESEARCH

Clostridium perfringens Phospholipase C Induced ROS Production and Cytotoxicity Require PKC, MEK1 and NFκB Activation

(2014) Laura Monturiol-Gross et al.   PLoS One

Delphinidin prevents hypoxia-induced mouse embryonic stem cell apoptosis through reduction of intracellular reactive oxygen species-mediated activation of JNK and NF-κB, and Akt inhibition

(2013) Bit Na Seo et al.   APOPTOSIS

Influence of bacteria on epigenetic gene control

(2013) Kyoko Takahashi   CELLULAR AND MOLECULAR LIFE SCIENCES

LuxR Homologue SmcR Is Essential for Vibrio vulnificus Pathogenesis and Biofilm Detachment, and Its Expression is Induced by Host Cells

(2013) Seung Min Kim et al.   INFECTION AND IMMUNITY

Annexin A2 Regulates A Disintegrin and Metalloproteinase 17–mediated Ectodomain Shedding of Pro–Tumor Necrosis Factor-α in Monocytes and Colon Epithelial Cells

(2013) Hironobu Tsukamoto et al.   INFLAMMATORY BOWEL DISEASES

Caspase-1: The inflammasome and beyond

(2013) Gabriel Sollberger et al.   Innate Immunity

Regulation of haemolysin (VvhA) production by ferric uptake regulator (Fur) inVibrio vulnificus: repression ofvvhAtranscription by Fur and proteolysis of VvhA by Fur-repressive exoproteases

(2013) Hyun-Jung Lee et al.   MOLECULAR MICROBIOLOGY

Crosstalk between Autophagy and Inflammasomes

(2013) Jae-Min Yuk et al.   MOLECULES AND CELLS

Interactions of Pathogenic Bacteria with Autophagy Systems

(2012) Marija Cemma et al.   CURRENT BIOLOGY

Cell Signaling through Protein Kinase C Oxidation and Activation

(2012) Daniela Cosentino-Gomes et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Autophagy plays an essential role in the clearance of Pseudomonas aeruginosa by alveolar macrophages

(2012) K. Yuan et al.   JOURNAL OF CELL SCIENCE

A Bacterial RTX Toxin Causes Programmed Necrotic Cell Death Through Calcium-Mediated Mitochondrial Dysfunction

(2012) Young Ran Kim et al.   JOURNAL OF INFECTIOUS DISEASES

NLRP3 inflammasome induces chemotactic immune cell migration to the CNS in experimental autoimmune encephalomyelitis

(2012) M. Inoue et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Additive Function of Vibrio vulnificus MARTXVv and VvhA Cytolysins Promotes Rapid Growth and Epithelial Tissue Necrosis During Intestinal Infection

(2012) Hee-Gon Jeong et al.   PLoS Pathogens

Autophagy-based unconventional secretory pathway for extracellular delivery of IL-1β

(2011) Nicolas Dupont et al.   EMBO JOURNAL

Deregulated inflammasome signaling in disease

(2011) Mohamed Lamkanfi et al.   IMMUNOLOGICAL REVIEWS

RTX Toxin Enhances the Survival of Vibrio vulnificus During Infection by Protecting the Organism From Phagocytosis

(2011) Horng-Ren Lo et al.   JOURNAL OF INFECTIOUS DISEASES

Pathogenic Vibrio Activate NLRP3 Inflammasome via Cytotoxins and TLR/Nucleotide-Binding Oligomerization Domain-Mediated NF- B Signaling

(2010) C. Toma et al.   JOURNAL OF IMMUNOLOGY

IL-1β Processing in Host Defense: Beyond the Inflammasomes

(2010) Mihai G. Netea et al.   PLoS Pathogens

DNA demethylation at specific CpG sites in theIL1Bpromoter in response to inflammatory cytokines in human articular chondrocytes

(2009) Ko Hashimoto et al.   ARTHRITIS AND RHEUMATISM

Redox signaling via lipid raft clustering in homocysteine-induced injury of podocytes

(2009) Chun Zhang et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Lipid Rafts and Caveolin-1 Coordinate Interleukin-1β (IL-1β)-dependent Activation of NFκB by Controlling Endocytosis of Nox2 and IL-1β Receptor 1 from the Plasma Membrane

(2009) Fredrick D. Oakley et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Arachidonic acid release by H2O2mediated proliferation of mouse embryonic stem cells: Involvement of Ca2+/PKC and MAPKs-induced EGFR transactivation

(2009) Sang Hun Lee et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Effect of arachidonic acid on hypoxia-induced IL-6 production in mouse ES cells: Involvement of MAPKs, NF-κB, and HIF-1α

(2009) Sang Hun Lee et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Insights into the Bacterial Transferrin Receptor: The Structure of Transferrin-Binding Protein B from Actinobacillus pleuropneumoniae

(2009) Trevor F. Moraes et al.   MOLECULAR CELL

Annexin A2 at the interface between F-actin and membranes enriched in phosphatidylinositol 4,5,-bisphosphate

(2008) Matthew J. Hayes et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

ATP-induced autophagy is associated with rapid killing of intracellular mycobacteria within human monocytes/macrophages

(2008) Debasis Biswas et al.   BMC IMMUNOLOGY

Signal cross talks for sustained MAPK activation and cell migration: the potential role of reactive oxygen species

(2008) Wen-Sheng Wu et al.   CANCER AND METASTASIS REVIEWS

Cell death in the host response to infection

(2008) K Labbé et al.   CELL DEATH AND DIFFERENTIATION

Salmonella AvrA Coordinates Suppression of Host Immune and Apoptotic Defenses via JNK Pathway Blockade

(2008) Rheinallt M. Jones et al.   Cell Host & Microbe

The Atg8 and Atg12 ubiquitin-like conjugation systems in macroautophagy. ‘Protein Modifications: Beyond the Usual Suspects’ Review Series

(2008) Jiefei Geng et al.   EMBO REPORTS

Differential regulation of ERK1/2 and p38 MAP kinases in VacA-induced apoptosis of gastric epithelial cells

(2007) Mi-Ran Ki et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY