(Q)SARs to predict environmental toxicities: current status and future needs

In vitro testing of basal cytotoxicity: Establishment of an adverse outcome pathway from chemical insult to cell death

(2017) Mathieu Vinken et al.   TOXICOLOGY IN VITRO

Classification of baseline toxicants for QSAR predictions to replace fish acute toxicity studies

(2017) Monika Nendza et al.   Environmental Science-Processes & Impacts

In silico environmental chemical science: properties and processes from statistical and computational modelling

(2017) Paul G. Tratnyek et al.   Environmental Science-Processes & Impacts

History of EPI Suite™ and future perspectives on chemical property estimation in US Toxic Substances Control Act new chemical risk assessments

(2017) Marcella L. Card et al.   Environmental Science-Processes & Impacts

General baseline toxicity QSAR for nonpolar, polar and ionisable chemicals and their mixtures in the bioluminescence inhibition assay with Aliivibrio fischeri

(2017) Beate I. Escher et al.   Environmental Science-Processes & Impacts

ToxCast Chemical Landscape: Paving the Road to 21st Century Toxicology

(2016) Ann M. Richard et al.   CHEMICAL RESEARCH IN TOXICOLOGY

Development of a general baseline toxicity QSAR model for the fish embryo acute toxicity test

(2016) Nils Klüver et al.   CHEMOSPHERE

Adverse Outcome Pathway (AOP) Informed Modeling of Aquatic Toxicology: QSARs, Read-Across, and Interspecies Verification of Modes of Action

(2016) Claire M. Ellison et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

Response to Comment on “Application of the Activity Framework for Assessing Aquatic Ecotoxicology Data for Organic Chemicals”

(2016) Paul Thomas et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

Comment on “Application of the Activity Framework for Assessing Aquatic Ecotoxicology Data for Organic Chemicals”

(2016) Kai-Uwe Goss et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

Quantifying the benefits of using read-across and in silico techniques to fulfill hazard data requirements for chemical categories

(2016) Kathleen Stanton et al.   REGULATORY TOXICOLOGY AND PHARMACOLOGY

MOAtox: A comprehensive mode of action and acute aquatic toxicity database for predictive model development

(2015) M.G. Barron et al.   AQUATIC TOXICOLOGY

Investigation of the Verhaar scheme for predicting acute aquatic toxicity: Improving predictions obtained from Toxtree ver. 2.6

(2015) Claire M. Ellison et al.   CHEMOSPHERE

Systems Biology Approach Reveals a Calcium-Dependent Mechanism for Basal Toxicity in Daphnia magna

(2015) Philipp Antczak et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

Application of the Activity Framework for Assessing Aquatic Ecotoxicology Data for Organic Chemicals

(2015) Paul Thomas et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

It is time to develop ecological thresholds of toxicological concern to assist environmental hazard assessment

(2015) Scott E. Belanger et al.   ENVIRONMENTAL TOXICOLOGY AND CHEMISTRY

Ecotoxicological thresholds-practical application to an industrial inventory

(2015) Steve Gutsell et al.   ENVIRONMENTAL TOXICOLOGY AND CHEMISTRY

Data quality and relevance in ecotoxicity: The undocumented influences of model assumptions and modifying factors on aquatic toxicity dose metrics

(2015) L.S. McCarty   REGULATORY TOXICOLOGY AND PHARMACOLOGY

Adverse Outcome Pathways for Regulatory Applications: Examination of Four Case Studies With Different Degrees of Completeness and Scientific Confidence

(2015) Edward J. Perkins et al.   TOXICOLOGICAL SCIENCES

Genomic data integration for ecological and evolutionary traits in non-model organisms

(2014) Denis Tagu et al.   BMC GENOMICS

Principles of Sound Ecotoxicology

(2014) Catherine A. Harris et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

Applying Adverse Outcome Pathways (AOPs) to support Integrated Approaches to Testing and Assessment (IATA)

(2014) Knut Erik Tollefsen et al.   REGULATORY TOXICOLOGY AND PHARMACOLOGY

Development of a chronic fish toxicity model for predicting sub-lethal NOEC values for non-polar narcotics

(2014) T.J. Austin et al.   SAR AND QSAR IN ENVIRONMENTAL RESEARCH

Time-dependence in mixture toxicity prediction

(2014) Douglas A. Dawson et al.   TOXICOLOGY

Molecular target sequence similarity as a basis for species extrapolation to assess the ecological risk of chemicals with known modes of action

(2013) Carlie A. LaLone et al.   AQUATIC TOXICOLOGY

From data point timelines to a well curated data set, data mining of experimental data and chemical structure data from scientific articles, problems and possible solutions

(2013) Villu Ruusmann et al.   JOURNAL OF COMPUTER-AIDED MOLECULAR DESIGN

Read-Across Prediction of the Acute Toxicity of Organic Compounds toward the Water FleaDaphnia magna

(2013) Ralph Kühne et al.   Molecular Informatics

Metabolomics: A tool for early detection of toxicological effects and an opportunity for biology based grouping of chemicals—From QSAR to QBAR

(2012) B. van Ravenzwaay et al.   MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS

VirtualToxLab — A platform for estimating the toxic potential of drugs, chemicals and natural products

(2012) Angelo Vedani et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

A review of the electrophilic reaction chemistry involved in covalent protein binding relevant to toxicity

(2011) S. J. Enoch et al.   CRITICAL REVIEWS IN TOXICOLOGY

Some Good Reasons to Ban ECxand Related Concepts in Ecotoxicology

(2011) Tjalling Jager   ENVIRONMENTAL SCIENCE & TECHNOLOGY

Bad habits die hard: The NOEC's persistence reflects poorly on ecotoxicology

(2011) Tjalling Jager   ENVIRONMENTAL TOXICOLOGY AND CHEMISTRY

Adverse Outcome Pathways during Early Fish Development: A Conceptual Framework for Identification of Chemical Screening and Prioritization Strategies

(2011) David C. Volz et al.   TOXICOLOGICAL SCIENCES

Modelling acute oral mammalian toxicity. 1. Definition of a quantifiable baseline effect

(2011) Yana K. Koleva et al.   TOXICOLOGY IN VITRO

Adverse outcome pathways: A conceptual framework to support ecotoxicology research and risk assessment

(2010) Gerald T. Ankley et al.   ENVIRONMENTAL TOXICOLOGY AND CHEMISTRY

Classification of chemicals according to mechanism of aquatic toxicity: An evaluation of the implementation of the Verhaar scheme in Toxtree

(2008) S.J. Enoch et al.   CHEMOSPHERE

Definition of the structural domain of the baseline non-polar narcosis model forTetrahymena pyriformis†

(2008) C.M. Ellison et al.   SAR AND QSAR IN ENVIRONMENTAL RESEARCH