Addressing the ethical issues raised by synthetic human entities with embryo-like features

Assembly of embryonic and extraembryonic stem cells to mimic embryogenesis in vitro

(2017) Sarah Ellys Harrison et al.   SCIENCE

Midbrain-like Organoids from Human Pluripotent Stem Cells Contain Functional Dopaminergic and Neuromelanin-Producing Neurons

(2016) Junghyun Jo et al.   Cell Stem Cell

Policy: Global standards for stem-cell research

(2016) Jonathan Kimmelman et al.   NATURE

Embryology policy: Revisit the 14-day rule

(2016) Insoo Hyun et al.   NATURE

Self-organization of the in vitro attached human embryo

(2016) Alessia Deglincerti et al.   NATURE

Self-organization of the human embryo in the absence of maternal tissues

(2016) Marta N. Shahbazi et al.   NATURE CELL BIOLOGY

Building brains in a dish: Prospects for growing cerebral organoids from stem cells

(2016) John O. Mason et al.   NEUROSCIENCE

Can Artificial Intelligences Suffer from Mental Illness? A Philosophical Matter to Consider

(2016) Hutan Ashrafian   SCIENCE AND ENGINEERING ETHICS

Setting Global Standards for Stem Cell Research and Clinical Translation: The 2016 ISSCR Guidelines

(2016) George Q. Daley et al.   Stem Cell Reports

Bioprinting of 3D Convoluted Renal Proximal Tubules on Perfusable Chips

(2016) Kimberly A. Homan et al.   Scientific Reports

What if stem cells turn into embryos in a dish?

(2015) Martin F Pera et al.   NATURE METHODS

A prudent path forward for genomic engineering and germline gene modification

(2015) D. Baltimore et al.   SCIENCE

Stem Cell Terminology and ‘Synthetic' Embryos: A New Debate on Totipotency, Omnipotency, and Pluripotency and How It Relates to Recent Experimental Data

(2015) Hans-Werner Denker   CELLS TISSUES ORGANS

3D Bioprinting of Vascularized, Heterogeneous Cell-Laden Tissue Constructs

(2014) David B. Kolesky et al.   ADVANCED MATERIALS

Self-Organizing Properties of Mouse Pluripotent Cells Initiate Morphogenesis upon Implantation

(2014) Ivan Bedzhov et al.   CELL

Symmetry breaking, germ layer specification and axial organisation in aggregates of mouse embryonic stem cells

(2014) S. C. van den Brink et al.   DEVELOPMENT

Rapid neurogenesis through transcriptional activation in human stem cells

(2014) V. Busskamp et al.   Molecular Systems Biology

Modeling the mitochondrial cardiomyopathy of Barth syndrome with induced pluripotent stem cell and heart-on-chip technologies

(2014) Gang Wang et al.   NATURE MEDICINE

A method to recapitulate early embryonic spatial patterning in human embryonic stem cells

(2014) Aryeh Warmflash et al.   NATURE METHODS

Regulating gene drives

(2014) K. A. Oye et al.   SCIENCE

Organogenesis in a dish: Modeling development and disease using organoid technologies

(2014) M. A. Lancaster et al.   SCIENCE

Concerning RNA-guided gene drives for the alteration of wild populations

(2014) Kevin M Esvelt et al.   eLife

The Argument from Potentiality in the Embryo Protection Debate: Finally “Depotentialized”?

(2013) Marco Stier et al.   AMERICAN JOURNAL OF BIOETHICS

Cerebral organoids model human brain development and microcephaly

(2013) Madeline A. Lancaster et al.   NATURE

Barcoding cells using cell-surface programmable DNA-binding domains

(2013) Prashant Mali et al.   NATURE METHODS

In-vitro model systems for the study of human embryo–endometrium interactions

(2013) Charlotte H.E. Weimar et al.   REPRODUCTIVE BIOMEDICINE ONLINE

DNA-directed self-assembly of shape-controlled hydrogels

(2013) Hao Qi et al.   Nature Communications

Embryonic Heart Progenitors and Cardiogenesis

(2013) T. Brade et al.   Cold Spring Harbor Perspectives in Medicine

Microengineered physiological biomimicry: Organs-on-Chips

(2012) Dongeun Huh et al.   LAB ON A CHIP

Combined small-molecule inhibition accelerates developmental timing and converts human pluripotent stem cells into nociceptors

(2012) Stuart M Chambers et al.   NATURE BIOTECHNOLOGY

WHAT PUTS THE ‘YUCK’ IN THE YUCK FACTOR?

(2010) JUSSI NIEMELÄ   BIOETHICS

Developmental competence of immature and failed/abnormally fertilized human oocytes in nuclear transfer

(2010) Sohyun Lee McElroy et al.   REPRODUCTIVE BIOMEDICINE ONLINE

Developmental competence of parthenogenetic mouse and human embryos after chemical or electrical activation

(2010) Karen Versieren et al.   REPRODUCTIVE BIOMEDICINE ONLINE

When “personhood” begins in the embryo: Avoiding a Syllabus of Errors

(2008) Scott F. Gilbert   BIRTH DEFECTS RESEARCH PART C-EMBRYO TODAY-REVIEWS