Structure and topology around the cleavage site regulate post-translational cleavage of the HIV-1 gp160 signal peptide

Crystal structure of a substrate-engaged SecY protein-translocation channel

(2016) Long Li et al.   NATURE

Affinity Maturation of a Potent Family of HIV Antibodies Is Primarily Focused on Accommodating or Avoiding Glycans

(2015) Fernando Garces et al.   IMMUNITY

Ubiquitous Autofragmentation of Fluorescent Proteins Creates Abundant Defective Ribosomal Products (DRiPs) for Immunosurveillance

(2015) Jiajie Wei et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Engineering and exploitation of a fluorescent HIV-1 gp120 for live cell CD4 binding assays

(2015) Lindsey M. Costantini et al.   VIROLOGY

Structure of the Mammalian Ribosome-Sec61 Complex to 3.4 Å Resolution

(2014) Rebecca M. Voorhees et al.   CELL

Inefficient SRP Interaction with a Nascent Chain Triggers a mRNA Quality Control Pathway

(2014) Andrey L. Karamyshev et al.   CELL

Structures of the Sec61 complex engaged in nascent peptide translocation or membrane insertion

(2014) Marko Gogala et al.   NATURE

Less is more: improving proteostasis by translation slow down

(2013) Michael Y. Sherman et al.   TRENDS IN BIOCHEMICAL SCIENCES

HIV-1 Diversity in the Envelope Glycoproteins: Implications for Viral Entry Inhibition

(2013) Leonardo Araújo et al.   Viruses-Basel

HIV-1 Assembly, Budding, and Maturation

(2013) W. I. Sundquist et al.   Cold Spring Harbor Perspectives in Medicine

HIV Entry and Envelope Glycoprotein-mediated Fusion

(2012) Robert Blumenthal et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Membrane Protein TM Segments Are Retained at the Translocon during Integration until the Nascent Chain Cues FRET-Detected Release into Bulk Lipid

(2012) Bo Hou et al.   MOLECULAR CELL

How Difficult Is It to Fold a Knotted Protein? In Silico Insights from Surface-Tethered Folding Experiments

(2012) Miguel A. Soler et al.   PLoS One

Transient interactions of a slow-folding protein with the Hsp70 chaperone machinery

(2012) Ashok Sekhar et al.   PROTEIN SCIENCE

The α-Helical Content of the Transmembrane Domain of the British Dementia Protein-2 (Bri2) Determines Its Processing by Signal Peptide Peptidase-like 2b (SPPL2b)

(2011) Regina Fluhrer et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Structural Determinants of Limited Proteolysis

(2011) Marat D. Kazanov et al.   JOURNAL OF PROTEOME RESEARCH

Sequence variations of Env signal peptide alleles in different clinical stages of HIV infection

(2011) Joaquim Xavier da Silva et al.   PEPTIDES

A Signature in HIV-1 Envelope Leader Peptide Associated with Transition from Acute to Chronic Infection Impacts Envelope Processing and Infectivity

(2011) Mohammed Asmal et al.   PLoS One

Structural studies of a signal peptide in complex with signal peptidase I cytoplasmic domain: The stabilizing effect of membrane-mimetics on the acquired fold

(2011) Paolo De Bona et al.   PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS

The Ribosome Modulates Nascent Protein Folding

(2011) C. M. Kaiser et al.   SCIENCE

Superfolder GFP Is Fluorescent in Oxidizing Environments When Targeted via the Sec Translocon

(2011) Deborah E. Aronson et al.   TRAFFIC

Recurrent Signature Patterns in HIV-1 B Clade Envelope Glycoproteins Associated with either Early or Chronic Infections

(2011) S. Gnanakaran et al.   PLoS Pathogens

Stabilized HIV-1 Envelope Glycoprotein Trimers Lacking the V1V2 Domain, Obtained by Virus Evolution

(2010) Ilja Bontjer et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Primary Folding Defect and Rescue of ΔF508 CFTR Emerge during Translation of the Mutant Domain

(2010) Hanneke Hoelen et al.   PLoS One

N-glycosylation efficiency is determined by the distance to the C-terminus and the amino acid preceding an Asn-Ser-Thr sequon

(2010) Manuel Bañó-Polo et al.   PROTEIN SCIENCE

Enzymatic assembly of DNA molecules up to several hundred kilobases

(2009) Daniel G Gibson et al.   NATURE METHODS

Structural and kinetic determinants of protease substrates

(2009) John C Timmer et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

A generic method for assignment of reliability scores applied to solvent accessibility predictions

(2009) Bent Petersen et al.   BMC STRUCTURAL BIOLOGY

Flanking signal and mature peptide residues influence signal peptide cleavage

(2008) Khar Choo et al.   BMC BIOINFORMATICS

Optimization of Human Immunodeficiency Virus Type 1 Envelope Glycoproteins with V1/V2 Deleted, Using Virus Evolution

(2008) I. Bontjer et al.   JOURNAL OF VIROLOGY

Selection of T1249-Resistant Human Immunodeficiency Virus Type 1 Variants

(2008) D. Eggink et al.   JOURNAL OF VIROLOGY

Only Five of 10 Strictly Conserved Disulfide Bonds Are Essential for Folding and Eight for Function of the HIV-1 Envelope Glycoprotein

(2008) Eelco van Anken et al.   MOLECULAR BIOLOGY OF THE CELL