A genomic lifespan program that reorganises the young adult brain is targeted in schizophrenia

Hierarchical organization and genetically separable subfamilies of PSD95 postsynaptic supercomplexes

(2017) René A. W. Frank et al.   JOURNAL OF NEUROCHEMISTRY

The contribution of rare variants to risk of schizophrenia in individuals with and without intellectual disability

(2017) Tarjinder Singh et al.   NATURE GENETICS

NMDA receptors are selectively partitioned into complexes and supercomplexes during synapse maturation

(2016) René A. W. Frank et al.   Nature Communications

Identification of Vulnerable Cell Types in Major Brain Disorders Using Single Cell Transcriptomes and Expression Weighted Cell Type Enrichment

(2016) Nathan G. Skene et al.   Frontiers in Neuroscience

Contrasting genetic architectures of schizophrenia and other complex diseases using fast variance-components analysis

(2015) Po-Ru Loh et al.   NATURE GENETICS

Novel Findings from CNVs Implicate Inhibitory and Excitatory Signaling Complexes in Schizophrenia

(2015) Andrew J. Pocklington et al.   NEURON

Cell types in the mouse cortex and hippocampus revealed by single-cell RNA-seq

(2015) A. Zeisel et al.   SCIENCE

Characterizing synaptic protein development in human visual cortex enables alignment of synaptic age with rat visual cortex

(2015) Joshua G. A. Pinto et al.   Frontiers in Neural Circuits

MAGMA: Generalized Gene-Set Analysis of GWAS Data

(2015) Christiaan A. de Leeuw et al.   PLoS Computational Biology

Novel insights into the development and maintenance of the blood–brain barrier

(2014) Britta Engelhardt et al.   CELL AND TISSUE RESEARCH

De novo mutations in schizophrenia implicate synaptic networks

(2014) Menachem Fromer et al.   NATURE

A polygenic burden of rare disruptive mutations in schizophrenia

(2014) Shaun M. Purcell et al.   NATURE

Biological insights from 108 schizophrenia-associated genetic loci

(2014)   NATURE

Haploinsufficiency of Dmxl2, Encoding a Synaptic Protein, Causes Infertility Associated with a Loss of GnRH Neurons in Mouse

(2014) Brooke Tata et al.   PLOS BIOLOGY

Spatial and Temporal Mapping of De Novo Mutations in Schizophrenia to a Fetal Prefrontal Cortical Network

(2013) Suleyman Gulsuner et al.   CELL

Coexpression Networks Implicate Human Midfetal Deep Cortical Projection Neurons in the Pathogenesis of Autism

(2013) A. Jeremy Willsey et al.   CELL

Integrative Functional Genomic Analyses Implicate Specific Molecular Pathways and Circuits in Autism

(2013) Neelroop N. Parikshak et al.   CELL

Modeling Transformations of Neurodevelopmental Sequences across Mammalian Species

(2013) A. D. Workman et al.   JOURNAL OF NEUROSCIENCE

Altered gene expression in the dorsolateral prefrontal cortex of individuals with schizophrenia

(2013) A L Guillozet-Bongaarts et al.   MOLECULAR PSYCHIATRY

Reversal of Behavioral Deficits and Synaptic Dysfunction in Mice Overexpressing Neuregulin 1

(2013) Dong-Min Yin et al.   NEURON

Comparing development of synaptic proteins in rat visual, somatosensory, and frontal cortex

(2013) Joshua G. A. Pinto et al.   Frontiers in Neural Circuits

DNA methylation age of human tissues and cell types

(2013) Steve Horvath   GENOME BIOLOGY

The sva package for removing batch effects and other unwanted variation in high-throughput experiments

(2012) Jeffrey T. Leek et al.   BIOINFORMATICS

Convergent functional genomics of schizophrenia: from comprehensive understanding to genetic risk prediction

(2012) M Ayalew et al.   MOLECULAR PSYCHIATRY

De novo mutations revealed by whole-exome sequencing are strongly associated with autism

(2012) Stephan J. Sanders et al.   NATURE

De novo gene mutations highlight patterns of genetic and neural complexity in schizophrenia

(2012) Bin Xu et al.   NATURE GENETICS

Synaptic scaffold evolution generated components of vertebrate cognitive complexity

(2012) Jess Nithianantharajah et al.   NATURE NEUROSCIENCE

Psychiatric disorders in rapid-onset dystonia-parkinsonism

(2012) A. Brashear et al.   NEUROLOGY

De Novo Gene Disruptions in Children on the Autistic Spectrum

(2012) Ivan Iossifov et al.   NEURON

Microglia Sculpt Postnatal Neural Circuits in an Activity and Complement-Dependent Manner

(2012) Dorothy P. Schafer et al.   NEURON

Diagnostic Exome Sequencing in Persons with Severe Intellectual Disability

(2012) Joep de Ligt et al.   NEW ENGLAND JOURNAL OF MEDICINE

Comprehensive Research Synopsis and Systematic Meta-Analyses in Parkinson's Disease Genetics: The PDGene Database

(2012) Christina M. Lill et al.   PLoS Genetics

LIBSVM

(2012) Chih-Chung Chang et al.   ACM Transactions on Intelligent Systems and Technology

Schizophrenia-associated HapICE haplotype is associated with increased NRG1 type III expression and high nucleotide diversity

(2012) C S Weickert et al.   Translational Psychiatry

A novel role for PSD-95 in mediating ethanol intoxication, drinking and place preference

(2011) Marguerite C. Camp et al.   ADDICTION BIOLOGY

Keeping up with genetic discoveries in amyotrophic lateral sclerosis: The ALSoD and ALSGene databases

(2011) Christina M. Lill et al.   Amyotrophic Lateral Sclerosis

De novo CNV analysis implicates specific abnormalities of postsynaptic signalling complexes in the pathogenesis of schizophrenia

(2011) G Kirov et al.   MOLECULAR PSYCHIATRY

Spatio-temporal transcriptome of the human brain

(2011) Hyo Jung Kang et al.   NATURE

Temporal dynamics and genetic control of transcription in the human prefrontal cortex

(2011) Carlo Colantuoni et al.   NATURE

Increased exonic de novo mutation rate in individuals with schizophrenia

(2011) Simon L Girard et al.   NATURE GENETICS

Diffusion tensor imaging of white matter tract evolution over the lifespan

(2011) C. Lebel et al.   NEUROIMAGE

Early Recognition and Disease Prediction in the At-Risk Mental States for Psychosis Using Neurocognitive Pattern Classification

(2011) Nikolaos Koutsouleris et al.   SCHIZOPHRENIA BULLETIN

Epigenetic dysregulation of HTR2A in the brain of patients with schizophrenia and bipolar disorder

(2011) Hamid Mostafavi Abdolmaleky et al.   SCHIZOPHRENIA RESEARCH

Prenatal Infection and Schizophrenia: A Review of Epidemiologic and Translational Studies

(2010) Alan S. Brown et al.   AMERICAN JOURNAL OF PSYCHIATRY

The neuropsychiatric phenotype in Darier disease

(2010) K. Gordon-Smith et al.   BRITISH JOURNAL OF DERMATOLOGY

Mutation screening of spastin, atlastin, and REEP1 in hereditary spastic paraplegia

(2010) DS McCorquodale et al.   CLINICAL GENETICS

Characterization of the proteome, diseases and evolution of the human postsynaptic density

(2010) Àlex Bayés et al.   NATURE NEUROSCIENCE

The Mouse Blood-Brain Barrier Transcriptome: A New Resource for Understanding the Development and Function of Brain Endothelial Cells

(2010) Richard Daneman et al.   PLoS One

Heritability of age of onset of psychosis in schizophrenia

(2009) Elizabeth Hare et al.   AMERICAN JOURNAL OF MEDICAL GENETICS PART B-NEUROPSYCHIATRIC GENETICS

PSD-95 Is Essential for Hallucinogen and Atypical Antipsychotic Drug Actions at Serotonin Receptors

(2009) A. I. Abbas et al.   JOURNAL OF NEUROSCIENCE

A SNAP25 promoter variant is associated with early-onset bipolar disorder and a high expression level in brain

(2009) B Etain et al.   MOLECULAR PSYCHIATRY

Targeted tandem affinity purification of PSD-95 recovers core postsynaptic complexes and schizophrenia susceptibility proteins

(2009) Esperanza Fernández et al.   Molecular Systems Biology

A developmental study on the expression of PDGFαR immunoreactive cells in the brain of postnatal rats

(2009) Yangtao He et al.   NEUROSCIENCE RESEARCH

A re-annotation pipeline for Illumina BeadArrays: improving the interpretation of gene expression data

(2009) Nuno L. Barbosa-Morais et al.   NUCLEIC ACIDS RESEARCH

Transcriptional neoteny in the human brain

(2009) M. Somel et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The mammalian phenotype ontology: enabling robust annotation and comparative analysis

(2009) Cynthia L. Smith et al.   Wiley Interdisciplinary Reviews-Systems Biology and Medicine

lumi: a pipeline for processing Illumina microarray

(2008) P. Du et al.   BIOINFORMATICS

Evolutionary expansion and anatomical specialization of synapse proteome complexity

(2008) Richard D Emes et al.   NATURE NEUROSCIENCE