Intermittent Ca2+ signals mediated by Orai1 regulate basal T cell motility

ORAI2 modulates store-operated calcium entry and T cell-mediated immunity

(2017) Martin Vaeth et al.   Nature Communications

T-cell calcium dynamics visualized in a ratiometric tdTomato-GCaMP6f transgenic reporter mouse

(2017) Tobias X Dong et al.   eLife

The role of the store-operated calcium entry channel Orai1 in cultured rat hippocampal synapse formation and plasticity

(2016) Eduard Korkotian et al.   JOURNAL OF PHYSIOLOGY-LONDON

Calcium influx through CRAC channels controls actin organization and dynamics at the immune synapse

(2016) Catherine A Hartzell et al.   eLife

Signal strength regulates antigen-mediated T-cell deceleration by distinct mechanisms to promote local exploration or arrest

(2015) Hélène D. Moreau et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Imaging regulatory T cell dynamics and CTLA4-mediated suppression of T cell priming

(2015) Melanie P. Matheu et al.   Nature Communications

Detection of Rare Antigen-Presenting Cells through T Cell-Intrinsic Meandering Motility, Mediated by Myo1g

(2014) Audrey Gérard et al.   CELL

Modes and mechanisms of T cell motility: roles for confinement and Myosin-IIA

(2014) Matthew F Krummel et al.   CURRENT OPINION IN CELL BIOLOGY

Coordinate control of cytoskeletal remodeling and calcium mobilization during T-cell activation

(2014) Alexander Babich et al.   IMMUNOLOGICAL REVIEWS

The actin-bundling protein L-plastin supports T-cell motility and activation

(2014) Sharon Celeste Morley   IMMUNOLOGICAL REVIEWS

Single-molecule analysis of diffusion and trapping of STIM1 and Orai1 at endoplasmic reticulum–plasma membrane junctions

(2014) Minnie M. Wu et al.   MOLECULAR BIOLOGY OF THE CELL

Quantitative and unbiased analysis of directional persistence in cell migration

(2014) Roman Gorelik et al.   Nature Protocols

Interference with Ca2+release activated Ca2+(CRAC) channel function delays T-cell arrest in vivo

(2013) Janelle C. Waite et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Orai1 Function Is Essential for T Cell Homing to Lymph Nodes

(2013) M. L. Greenberg et al.   JOURNAL OF IMMUNOLOGY

Dendritic Cells Regulate High-Speed Interstitial T Cell Migration in the Lymph Node via LFA-1/ICAM-1

(2013) T. Katakai et al.   JOURNAL OF IMMUNOLOGY

KCa3.1 and TRPM7 Channels at the Uropod Regulate Migration of Activated Human T Cells

(2012) Zerrin Kuras et al.   PLoS One

Crystal Structure of the Calcium Release-Activated Calcium Channel Orai

(2012) X. Hou et al.   SCIENCE

A Decade of Imaging Cellular Motility and Interaction Dynamics in the Immune System

(2012) R. N. Germain et al.   SCIENCE

Migrational Guidance of Neutrophils Is Mechanotransduced via High-Affinity LFA-1 and Calcium Flux

(2011) N. Dixit et al.   JOURNAL OF IMMUNOLOGY

Regulation of T Cell Priming by Lymphoid Stroma

(2011) Omar Khan et al.   PLoS One

Confinement-optimized three-dimensional T cell amoeboid motility is modulated via myosin IIA–regulated adhesions

(2010) Jordan Jacobelli et al.   NATURE IMMUNOLOGY

Calpain 2 Controls Turnover of LFA-1 Adhesions on Migrating T Lymphocytes

(2010) Lena Svensson et al.   PLoS One

Cell-autonomous and environmental contributions to the interstitial migration of T cells

(2010) Paulus Mrass et al.   Seminars in Immunopathology

Orai1 regulates intracellular calcium, arrest, and shape polarization during neutrophil recruitment in shear flow

(2009) U. Y. Schaff et al.   BLOOD

The functional network of ion channels in T lymphocytes

(2009) Michael D. Cahalan et al.   IMMUNOLOGICAL REVIEWS

Random versus directionally persistent cell migration

(2009) Ryan J. Petrie et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Dynamic Movement of the Calcium Sensor STIM1 and the Calcium Channel Orai1 in Activated T-Cells: Puncta and Distal Caps

(2008) Valarie A. Barr et al.   MOLECULAR BIOLOGY OF THE CELL

Molecular Clustering of STIM1 with Orai1/CRACM1 at the Plasma Membrane Depends Dynamically on Depletion of Ca2+ Stores and on Electrostatic Interactions

(2008) Nathaniel Calloway et al.   MOLECULAR BIOLOGY OF THE CELL

Interstitial leukocyte migration and immune function

(2008) Peter Friedl et al.   NATURE IMMUNOLOGY

Orai1 and STIM1 move to the immunological synapse and are up-regulated during T cell activation

(2008) M. I. Lioudyno et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA