Kinesin motility driven by subdomain dynamics

Crystal structure of Zen4 in the apo state reveals a missing conformation of kinesin

(2017) Ruifang Guan et al.   Nature Communications

The Kinesin-1 Chemomechanical Cycle: Stepping Toward a Consensus

(2016) William O. Hancock   BIOPHYSICAL JOURNAL

Review: Mechanochemistry of the kinesin-1 ATPase

(2016) R. A. Cross   BIOPOLYMERS

Structural Basis of Backwards Motion in Kinesin-1-Kinesin-14 Chimera: Implication for Kinesin-14 Motility

(2016) Masahiko Yamagishi et al.   STRUCTURE

Decrypting the Structural, Dynamic, and Energetic Basis of a Monomeric Kinesin Interacting with a Tubulin Dimer in Three ATPase States by All-Atom Molecular Dynamics Simulation

(2015) Srirupa Chakraborty et al.   BIOCHEMISTRY

Mechanistic Origin of Microtubule Dynamic Instability and Its Modulation by EB Proteins

(2015) Rui Zhang et al.   CELL

X-ray and Cryo-EM structures reveal mutual conformational changes of Kinesin and GTP-state microtubules upon binding

(2015) M. Morikawa et al.   EMBO JOURNAL

The structural kinetics of switch-1 and the neck linker explain the functions of kinesin-1 and Eg5

(2015) Joseph M. Muretta et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Kinetics of nucleotide-dependent structural transitions in the kinesin-1 hydrolysis cycle

(2015) Keith J. Mickolajczyk et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Kinesin Kip2 enhances microtubule growth in vitro through length-dependent feedback on polymerization and catastrophe

(2015) Anneke Hibbel et al.   eLife

Examining kinesin processivity within a general gating framework

(2015) Johan OL Andreasson et al.   eLife

CHARMM Force-Fields with Modified Polyphosphate Parameters Allow Stable Simulation of the ATP-Bound Structure of Ca2+-ATPase

(2014) Yasuaki Komuro et al.   Journal of Chemical Theory and Computation

KIF14 Binds Tightly to Microtubules and Adopts a Rigor-Like Conformation

(2014) Kritica Arora et al.   JOURNAL OF MOLECULAR BIOLOGY

Regulation of microtubule motors by tubulin isotypes and post-translational modifications

(2014) Minhajuddin Sirajuddin et al.   NATURE CELL BIOLOGY

Comprehensive structural model of the mechanochemical cycle of a mitotic motor highlights molecular adaptations in the kinesin family

(2014) Adeline Goulet et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Kinesin processivity is gated by phosphate release

(2014) Bojan Milic et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The structure of apo-kinesin bound to tubulin links the nucleotide cycle to movement

(2014) Luyan Cao et al.   Nature Communications

High-resolution structures of kinesin on microtubules provide a basis for nucleotide-gated force-generation

(2014) Zhiguo Shang et al.   eLife

Conserved mechanisms of microtubule-stimulated ADP release, ATP binding, and force generation in transport kinesins

(2014) Joseph Atherton et al.   eLife

Structural Basis for the ATP-Induced Isomerization of Kinesin

(2013) Qing Chang et al.   JOURNAL OF MOLECULAR BIOLOGY

Adenosine Triphosphate Hydrolysis Mechanism in Kinesin Studied by Combined Quantum-Mechanical/Molecular-Mechanical Metadynamics Simulations

(2013) Matthew J. McGrath et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Structure of a kinesin–tubulin complex and implications for kinesin motility

(2013) Benoît Gigant et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

All-Atom Structural Investigation of Kinesin–Microtubule Complex Constrained by High-Quality Cryo-Electron-Microscopy Maps

(2012) Minghui Li et al.   BIOCHEMISTRY

The Structural Basis of Force Generation by the Mitotic Motor Kinesin-5

(2012) Adeline Goulet et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Ras and GTPase-activating protein (GAP) drive GTP into a precatalytic state as revealed by combining FTIR and biomolecular simulations

(2012) T. Rudack et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Molecular crowding creates traffic jams of kinesin motors on microtubules

(2012) C. Leduc et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Role of Hydration Force in the Self-Assembly of Collagens and Amyloid Steric Zipper Filaments

(2011) Krishnakumar M. Ravikumar et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

A universal pathway for kinesin stepping

(2011) Bason E Clancy et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

The Structure of the Kinesin-1 Motor-Tail Complex Reveals the Mechanism of Autoinhibition

(2011) H. Y. K. Kaan et al.   SCIENCE

Structural and Functional Insights into the Myosin Motor Mechanism

(2010) H. Lee Sweeney et al.   Annual Review of Biophysics

Loop L5 Acts as a Conformational Latch in the Mitotic Kinesin Eg5

(2010) William M. Behnke-Parks et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

An atomic-level mechanism for activation of the kinesin molecular motors

(2010) C. V. Sindelar et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mechanical Design of Translocating Motor Proteins

(2009) Wonmuk Hwang et al.   CELL BIOCHEMISTRY AND BIOPHYSICS

ATP Hydrolysis in Eg5 Kinesin Involves a Catalytic Two-water Mechanism

(2009) Courtney L. Parke et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

CHARMM: The biomolecular simulation program

(2009) B. R. Brooks et al.   JOURNAL OF COMPUTATIONAL CHEMISTRY

The Hydrolysis Activity of Adenosine Triphosphate in Myosin: A Theoretical Analysis of Anomeric Effects and the Nature of the Transition State†

(2009) Yang Yang et al.   JOURNAL OF PHYSICAL CHEMISTRY A

Traffic control: regulation of kinesin motors

(2009) Kristen J. Verhey et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Intracellular Transport and Kinesin Superfamily Proteins, KIFs: Structure, Function, and Dynamics

(2008) Nobutaka Hirokawa et al.   PHYSIOLOGICAL REVIEWS

Kinesin's cover-neck bundle folds forward to generate force

(2008) A. S. Khalil et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Force Generation in Kinesin Hinges on Cover-Neck Bundle Formation

(2008) Wonmuk Hwang et al.   STRUCTURE

Allosteric Communication in Myosin V: From Small Conformational Changes to Large Directed Movements

(2008) M. Cecchini et al.   PLoS Computational Biology