Suppression of Hepatic Epithelial-to-Mesenchymal Transition by Melittin via Blocking of TGFβ/Smad and MAPK-JNK Signaling Pathways

Enhancement of hepatocyte differentiation from human embryonic stem cells by Chinese medicine Fuzhenghuayu

(2016) Jiamei Chen et al.   Scientific Reports

Xanthii fructus extract inhibits TNF-α/IFN-γ-induced Th2-chemokines production via blockade of NF-κB, STAT1 and p38-MAPK activation in human epidermal keratinocytes

(2015) Ji-Hyun Park et al.   JOURNAL OF ETHNOPHARMACOLOGY

Effects of Melittin Treatment in Cholangitis and Biliary Fibrosis in a Model of Xenobiotic-Induced Cholestasis in Mice

(2015) Kyung-Hyun Kim et al.   Toxins

Gamma-linolenic acid inhibits hepatic PAI-1 expression by inhibiting p38 MAPK-dependent activator protein and mitochondria-mediated apoptosis pathway

(2014) Ji-Hyun Park et al.   APOPTOSIS

Apamin inhibits hepatic fibrosis through suppression of transforming growth factor β1-induced hepatocyte epithelial–mesenchymal transition

(2014) Woo-Ram Lee et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

The Protective Effects of Melittin on Propionibacterium acnes –Induced Inflammatory Responses In Vitro and In Vivo

(2014) Woo-Ram Lee et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Molecular mechanisms of epithelial–mesenchymal transition

(2014) Samy Lamouille et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

What's new in liver fibrosis? The origin of myofibroblasts in liver fibrosis

(2012) Keiko Iwaisako et al.   JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY

Hepatic stellate cell progenitor cells

(2012) Kinji Asahina   JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY

Protective effect of melittin on inflammation and apoptosis in acute liver failure

(2011) Ji-Hyun Park et al.   APOPTOSIS

miR-30 inhibits TGF-β1-induced epithelial-to-mesenchymal transition in hepatocyte by targeting Snail1

(2011) Jingcheng Zhang et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Melittin attenuates liver injury in thioacetamide-treated mice through modulating inflammation and fibrogenesis

(2011) Ji-Hyun Park et al.   EXPERIMENTAL BIOLOGY AND MEDICINE

Sorafenib inhibits transforming growth factor β1-Mediated Epithelial-Mesenchymal Transition and apoptosis in mouse hepatocytes

(2011) Yue-Lei Chen et al.   HEPATOLOGY

Melittin Inhibits Atherosclerosis in LPS/High-Fat Treated Mice Through Atheroprotective Actions

(2011) Soo-Jung Kim et al.   Journal of Atherosclerosis and Thrombosis

Protective effects of melittin on transforming growth factor-β1 injury to hepatocytes via anti-apoptotic mechanism

(2011) Woo-Ram Lee et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Histone deacetylase inhibition suppresses the transforming growth factor β1-induced epithelial-to-mesenchymal transition in hepatocytes

(2010) Aki Kaimori et al.   HEPATOLOGY

Hedgehog pathway activation and epithelial-to-mesenchymal transitions during myofibroblastic transformation of rat hepatic cells in culture and cirrhosis

(2009) Steve S. Choi et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

TGF-β-induced epithelial to mesenchymal transition

(2009) Jian Xu et al.   CELL RESEARCH

Hepatocyte nuclear factor 4  attenuates hepatic fibrosis in rats

(2009) H.-Y. Yue et al.   GUT

Nitric oxide suppresses transforming growth factor-β1-induced epithelial-to-mesenchymal transition and apoptosis in mouse hepatocytes

(2009) Xinchao Pan et al.   HEPATOLOGY

Bee venom suppresses LPS-mediated NO/iNOS induction through inhibition of PKC-α expression

(2009) Kwang-Gill Lee et al.   JOURNAL OF ETHNOPHARMACOLOGY

Antifibrotic effect through the regulation of transcription factor using ring type-Sp1 decoy oligodeoxynucleotide in carbon tetrachloride-induced liver fibrosis

(2009) Ji-Hyun Park et al.   JOURNAL OF GENE MEDICINE

Murine cirrhosis induces hepatocyte epithelial mesenchymal transition and alterations in survival signaling pathways

(2008) Takashi Nitta et al.   HEPATOLOGY

Alpha-lipoic acid decreases hepatic lipogenesis through adenosine monophosphate-activated protein kinase (AMPK)-dependent and AMPK-independent pathways

(2008) Keun-Gyu Park et al.   HEPATOLOGY

Jun N-terminal kinase 1 regulates epithelial-to-mesenchymal transition induced by TGF- 1

(2008) J. F. Alcorn et al.   JOURNAL OF CELL SCIENCE

Transforming growth factor-β and hepatocyte transdifferentiation in liver fibrogenesis

(2008) Nadja M Meindl-Beinker et al.   JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY

Liver cirrhosis

(2008) Detlef Schuppan et al.   LANCET

Defining therapeutic targets for liver fibrosis: Exploiting the biology of inflammation and repair

(2008) J IREDALE   PHARMACOLOGICAL RESEARCH