Role of Arf GTPases in fungal morphogenesis and virulence

The Golgi apparatus: insights from filamentous fungi

(2016) Areti Pantazopoulou   MYCOLOGIA

Unfolded protein response regulates yeast small GTPase Arl1p activation at late Golgi via phosphorylation of Arf GEF Syt1p

(2016) Jia-Wei Hsu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Structural Insights into Arl1-Mediated Targeting of the Arf-GEF BIG1 to the trans-Golgi

(2016) Antonio Galindo et al.   Cell Reports

Polarized Exocytosis Induces Compensatory Endocytosis by Sec4p-Regulated Cortical Actin Polymerization

(2016) Jesper Johansen et al.   PLOS BIOLOGY

A quantitative imaging-based screen reveals the exocyst as a network hub connecting endocytosis and exocytosis

(2015) Mini Jose et al.   MOLECULAR BIOLOGY OF THE CELL

Phosphatidylinositol-4-phosphate-dependent membrane traffic is critical for fungal filamentous growth

(2015) Vikram Ghugtyal et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Endocytosis and exocytosis in hyphal growth

(2015) Zachary S. Schultzhaus et al.   Fungal Biology Reviews

Four GTPases Differentially Regulate the Sec7 Arf-GEF to Direct Traffic at the trans-Golgi Network

(2014) Caitlin M. McDonold et al.   DEVELOPMENTAL CELL

Novel Mechanism Coupling Cyclic AMP-Protein Kinase A Signaling and Golgi Trafficking via Gyp1 Phosphorylation in Polarized Growth

(2014) Zhen-Xing Huang et al.   EUKARYOTIC CELL

GBF/Gea mutant with a single substitution sustains fungal growth in the absence of BIG/Sec7

(2014) Herbert N. Arst et al.   FEBS LETTERS

Arfs at a Glance

(2014) C. L. Jackson et al.   JOURNAL OF CELL SCIENCE

Secretory Vesicles Deliver Cdc42p to Sites of Polarized Growth in S. cerevisiae

(2014) Shubha A. Dighe et al.   PLoS One

Quantitative Analysis of Membrane Trafficking in Regulation of Cdc42 Polarity

(2014) Leah J. Watson et al.   TRAFFIC

The Spatial Distribution of the Exocyst and Actin Cortical Patches Is Sufficient To Organize Hyphal Tip Growth

(2013) David Caballero-Lima et al.   EUKARYOTIC CELL

Role of Retrograde Trafficking in Stress Response, Host Cell Interactions, and Virulence of Candida albicans

(2013) Yaoping Liu et al.   EUKARYOTIC CELL

The Sec7 Guanine Nucleotide Exchange Factor GBF1 Regulates Membrane Recruitment of BIG1 and BIG2 Guanine Nucleotide Exchange Factors to theTrans-Golgi Network (TGN)

(2013) Jason Lowery et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Golgi enlargement in Arf-depleted yeast cells is due to altered dynamics of cisternal maturation

(2013) M. Bhave et al.   JOURNAL OF CELL SCIENCE

Arf3p GTPase is a key regulator of Bud2p activation for invasive growth in Saccharomyces cerevisiae

(2013) Jia-Wei Hsu et al.   MOLECULAR BIOLOGY OF THE CELL

Spatiotemporal regulation of Rho1 and Cdc42 activity duringCandida albicansfilamentous growth

(2013) Vincent Corvest et al.   MOLECULAR MICROBIOLOGY

Arl1p regulates spatial membrane organization at the trans-Golgi network through interaction with Arf-GEF Gea2p and flippase Drs2p

(2013) P.-C. Tsai et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

GTPase Networks in Membrane Traffic

(2012) Emi Mizuno-Yamasaki et al.   Annual Review of Biochemistry

The Sec7 Arf-GEF Is Recruited to the trans-Golgi Network by Positive Feedback

(2012) Brian C. Richardson et al.   DEVELOPMENTAL CELL

The small G protein Arl1 directs the trans-Golgi–specific targeting of the Arf1 exchange factors BIG1 and BIG2

(2012) Chantal Christis et al.   JOURNAL OF CELL BIOLOGY

A steep phosphoinositide bis-phosphate gradient forms during fungal filamentous growth

(2012) Aurélia Vernay et al.   JOURNAL OF CELL BIOLOGY

Competition between the golgin Imh1p and the GAP Gcs1p stabilizes activated Arl1p at the late-Golgi

(2012) K.-Y. Chen et al.   JOURNAL OF CELL SCIENCE

Cdc28–Cln3 phosphorylation of Sla1 regulates actin patch dynamics in different modes of fungal growth

(2012) Guisheng Zeng et al.   MOLECULAR BIOLOGY OF THE CELL

Mouse model of oropharyngeal candidiasis

(2012) Norma V Solis et al.   Nature Protocols

Candida albicansdimorphism as a therapeutic target

(2011) Ilse D Jacobsen et al.   Expert Review of Anti-Infective Therapy

Comparison of the influence of small GTPases Arl1 and Ypt6 on yeast cells’ tolerance to various stress factors

(2011) Lydie Marešová et al.   FEMS YEAST RESEARCH

Regulatory Circuitry Governing Fungal Development, Drug Resistance, and Disease

(2011) R. S. Shapiro et al.   MICROBIOLOGY AND MOLECULAR BIOLOGY REVIEWS

Dysregulated Arl1, a regulator of post-Golgi vesicle tethering, can inhibit endosomal transport and cell proliferation in yeast

(2011) Jeremy J. R. Benjamin et al.   MOLECULAR BIOLOGY OF THE CELL

Exo-endocytic trafficking and the septin-based diffusion barrier are required for the maintenance of Cdc42p polarization during budding yeast asymmetric growth

(2011) Kelly Orlando et al.   MOLECULAR BIOLOGY OF THE CELL

Phosphatidylserine is polarized and required for proper Cdc42 localization and for development of cell polarity

(2011) Gregory D. Fairn et al.   NATURE CELL BIOLOGY

Growth of Candida albicans hyphae

(2011) Peter E. Sudbery   NATURE REVIEWS MICROBIOLOGY

ARF family G proteins and their regulators: roles in membrane transport, development and disease

(2011) Julie G. Donaldson et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Quantitative Proteomics of Yeast Post-Golgi Vesicles Reveals a Discriminating Role for Sro7p in Protein Secretion

(2011) Annabelle Forsmark et al.   TRAFFIC

Rab GEFs and GAPs

(2010) Francis Barr et al.   CURRENT OPINION IN CELL BIOLOGY

Spitzenkörper, Exocyst, and Polarisome Components in Candida albicans Hyphae Show Different Patterns of Localization and Have Distinct Dynamic Properties

(2010) Laura A. Jones et al.   EUKARYOTIC CELL

Arf GAPs: Gatekeepers of vesicle generation

(2010) Anne Spang et al.   FEBS LETTERS

Syt1p promotes activation of Arl1p at the late Golgi to recruit Imh1p

(2010) K.-Y. Chen et al.   JOURNAL OF CELL SCIENCE

The Candida albicans ELMO homologue functions together with Rac1 and Dck1, upstream of the MAP Kinase Cek1, in invasive filamentous growth

(2010) Hannah Hope et al.   MOLECULAR MICROBIOLOGY

Candida albicans AGE3, the Ortholog of the S. cerevisiae ARF-GAP-Encoding Gene GCS1, Is Required for Hyphal Growth and Drug Resistance

(2010) Thomas Lettner et al.   PLoS One

Coordination of intracellular transport steps by GTPases

(2010) Nava Segev   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Reverse Genetics in Candida albicans Predicts ARF Cycling Is Essential for Drug Resistance and Virulence

(2010) Elias Epp et al.   PLoS Pathogens

Immobilization of the Glycosylphosphatidylinositol-anchored Gas1 Protein into the Chitin Ring and Septum Is Required for Proper Morphogenesis in Yeast

(2009) Eleonora Rolli et al.   MOLECULAR BIOLOGY OF THE CELL

Aspergillus nidulansArfB Plays a Role in Endocytosis and Polarized Growth

(2008) Soo Chan Lee et al.   EUKARYOTIC CELL

Secreted proteins of Candida albicans

(2008) Olga Hruskova-Heidingsfeldova   Frontiers in Bioscience-Landmark

Afi1p Functions as an Arf3p Polarization-specific Docking Factor for Development of Polarity

(2008) Pei-Chin Tsai et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Activation of Rac1 by the Guanine Nucleotide Exchange Factor Dck1 Is Required for Invasive Filamentous Growth in the Pathogen Candida albicans

(2008) Hannah Hope et al.   MOLECULAR BIOLOGY OF THE CELL

Yeast Arf3p Modulates Plasma Membrane PtdIns(4,5)P2 Levels to Facilitate Endocytosis

(2008) Iwona I. Smaczynska-de Rooij et al.   TRAFFIC

Aspergillus nidulans hypB encodes a Sec7-domain protein important for hyphal morphogenesis

(2007) Yi Yang et al.   FUNGAL GENETICS AND BIOLOGY