Multiple Protein Kinases via Activation of Transcription Factors NF-κB, AP-1 and C/EBP-δ Regulate the IL-6/IL-8 Production by HIV-1 Vpr in Astrocytes

Inhibition of SAPK/JNK leads to enhanced IL-1-induced IL-6 synthesis in osteoblasts

(2013) Akira Kondo et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

Monocyte/macrophages and their role in HIV neuropathogenesis

(2013) Tricia H. Burdo et al.   IMMUNOLOGICAL REVIEWS

Human immunodeficiency virus type 1 viral protein R (Vpr) induces CCL5 expression in astrocytes via PI3K and MAPK signaling pathways

(2013) Mohitkumar R Gangwani et al.   Journal of Neuroinflammation

Extracellular HIV-1 viral protein R affects astrocytic glyceraldehyde 3-phosphate dehydrogenase activity and neuronal survival

(2013) Adriano Ferrucci et al.   JOURNAL OF NEUROVIROLOGY

CCAAT/enhancer binding protein δ regulates glial proinflammatory gene expression

(2013) Tony Valente et al.   NEUROBIOLOGY OF AGING

HIV-1 Vpr activates both canonical and noncanonical NF-κB pathway by enhancing the phosphorylation of IKKα/β

(2013) Ruikang Liu et al.   VIROLOGY

CCAAT/Enhancer-Binding Protein δ Is a Critical Mediator of Lipopolysaccharide-Induced Acute Lung Injury

(2012) Chunguang Yan et al.   AMERICAN JOURNAL OF PATHOLOGY

Neuronal apoptosis by HIV-1 Vpr: contribution of proinflammatory molecular networks from infected target cells

(2012) Debjani Guha et al.   Journal of Neuroinflammation

An AP-1 Binding Site in the Enhancer/Core Element of the HIV-1 Promoter Controls the Ability of HIV-1 To Establish Latent Infection

(2012) A. Duverger et al.   JOURNAL OF VIROLOGY

Synergistic Cooperation between Methamphetamine and HIV-1 gsp120 through the P13K/Akt Pathway Induces IL-6 but not IL-8 Expression in Astrocytes

(2012) Ankit Shah et al.   PLoS One

Excess Soluble CD40L Contributes to Blood Brain Barrier Permeability In Vivo: Implications for HIV-Associated Neurocognitive Disorders

(2012) Donna C. Davidson et al.   PLoS One

Breaking down the barrier: The effects of HIV-1 on the blood–brain barrier

(2011) Marianne Strazza et al.   BRAIN RESEARCH

The role of JNK in the development of hepatocellular carcinoma

(2011) Madhumita Das et al.   GENES & DEVELOPMENT

Deregulation of microRNAs by HIV-1 Vpr Protein Leads to the Development of Neurocognitive Disorders

(2011) Ruma Mukerjee et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

HIV-1 gp120-mediated increases in IL-8 production in astrocytes are mediated through the NF-κB pathway and can be silenced by gp120-specific siRNA

(2011) Ankit Shah et al.   Journal of Neuroinflammation

Human Immunodeficiency Virus Infection of Human Astrocytes Disrupts Blood-Brain Barrier Integrity by a Gap Junction-Dependent Mechanism

(2011) E. A. Eugenin et al.   JOURNAL OF NEUROSCIENCE

HIV-1 gp120 Induces Expression of IL-6 through a Nuclear Factor-Kappa B-Dependent Mechanism: Suppression by gp120 Specific Small Interfering RNA

(2011) Ankit Shah et al.   PLoS One

HIV-1 Vpr induces TLR4/MyD88-mediated IL-6 production and reactivates viral production from latency

(2010) Shigeki Hoshino et al.   JOURNAL OF LEUKOCYTE BIOLOGY

HIV-associated neurocognitive disorders persist in the era of potent antiretroviral therapy: CHARTER Study

(2010) R. K. Heaton et al.   NEUROLOGY

Acid β-Glucosidase 1 Counteracts p38δ-dependent Induction of Interleukin-6

(2009) Kazuyuki Kitatani et al.   JOURNAL OF BIOLOGICAL CHEMISTRY