Enterovirus 71 protease 2Apro and 3Cpro differentially inhibit the cellular endoplasmic reticulum-associated degradation (ERAD) pathway via distinct mechanisms, and enterovirus 71 hijacks ERAD component p97 to promote its replication

Posttranscriptional Regulation of Glycoprotein Quality Control in the Endoplasmic Reticulum Is Controlled by the E2 Ub-Conjugating Enzyme UBC6e

(2016) Masatoshi Hagiwara et al.   MOLECULAR CELL

Fat(al) attraction: Picornaviruses Usurp Lipid Transfer at Membrane Contact Sites to Create Replication Organelles

(2016) Hilde M. van der Schaar et al.   TRENDS IN MICROBIOLOGY

Innate Immunity Evasion by Enteroviruses: Insights into Virus-Host Interaction

(2016) Xiaobo Lei et al.   Viruses-Basel

The Autophagic Machinery in Enterovirus Infection

(2016) Jeffrey Lai et al.   Viruses-Basel

Roles of the Picornaviral 3C Proteinase in the Viral Life Cycle and Host Cells

(2016) Di Sun et al.   Viruses-Basel

Endoplasmic Reticulum: The Favorite Intracellular Niche for Viral Replication and Assembly

(2016) Inés Romero-Brey et al.   Viruses-Basel

Human genome-wide RNAi screen reveals host factors required for enterovirus 71 replication

(2016) Kan Xing Wu et al.   Nature Communications

Dynamic lipid landscape of picornavirus replication organelles

(2016) George A Belov   Current Opinion in Virology

Meta- and Orthogonal Integration of Influenza “OMICs” Data Defines a Role for UBR4 in Virus Budding

(2015) Shashank Tripathi et al.   Cell Host & Microbe

Pathogenic Hijacking of ER-Associated Degradation: Is ERAD Flexible?

(2015) Daisuke Morito et al.   MOLECULAR CELL

Enterovirus replication: go with the (counter)flow

(2015) Jules Nchoutmboube et al.   TRENDS IN MICROBIOLOGY

Reciprocal Regulation between Enterovirus 71 and the NLRP3 Inflammasome

(2015) Hongbin Wang et al.   Cell Reports

Japanese encephalitis virus replication is negatively regulated by autophagy and occurs on LC3-I- and EDEM1-containing membranes

(2014) Manish Sharma et al.   Autophagy

Recent technical developments in the study of ER-associated degradation

(2014) Kunio Nakatsukasa et al.   CURRENT OPINION IN CELL BIOLOGY

Valosin-containing Protein-interacting Membrane Protein (VIMP) Links the Endoplasmic Reticulum with Microtubules in Concert with Cytoskeleton-linking Membrane Protein (CLIMP)-63

(2014) Chikano Noda et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Ube2g2-gp78-mediated HERP polyubiquitylation is involved in ER stress recovery

(2014) L. Yan et al.   JOURNAL OF CELL SCIENCE

Enterovirus 71 3C Inhibits Cytokine Expression through Cleavage of the TAK1/TAB1/TAB2/TAB3 Complex

(2014) X. Lei et al.   JOURNAL OF VIROLOGY

How Viruses Hijack the ERAD Tuning Machinery

(2014) J. Noack et al.   JOURNAL OF VIROLOGY

ERQC Autophagy: Yet Another Way to Die

(2014) Alexander Buchberger   MOLECULAR CELL

ERAD and how viruses exploit it

(2014) Hyewon Byun et al.   Frontiers in Microbiology

The ER quality control and ER associated degradation machineries are vital for viral pathogenesis

(2014) Jeanmarie Verchot   Frontiers in Plant Science

Derlin2 Protein Facilitates HRD1-mediated Retro-translocation of Sonic Hedgehog at the Endoplasmic Reticulum

(2013) Chih-Hsiang Huang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Role of HERP and a HERP-related Protein in HRD1-dependent Protein Degradation at the Endoplasmic Reticulum

(2013) Chih-Hsiang Huang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Interplays between Autophagy and Apoptosis Induced by Enterovirus 71

(2013) Xueyan Xi et al.   PLoS One

MHC class I molecules are preferentially ubiquitinated on endoplasmic reticulum luminal residues during HRD1 ubiquitin E3 ligase-mediated dislocation

(2013) M. L. Burr et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Specificity and Regulation of the Endoplasmic Reticulum-Associated Degradation Machinery

(2013) Jessica Merulla et al.   TRAFFIC

How Viruses Use the Endoplasmic Reticulum for Entry, Replication, and Assembly

(2013) T. Inoue et al.   Cold Spring Harbor Perspectives in Biology

Genome-wide RNAi Screen Identifies SEC61A and VCP as Conserved Regulators of Sindbis Virus Entry

(2013) Debasis Panda et al.   Cell Reports

Enterovirus 71 Protease 2Apro Targets MAVS to Inhibit Anti-Viral Type I Interferon Responses

(2013) Bei Wang et al.   PLoS Pathogens

An autophagy-independent role for LC3 in equine arteritis virus replication

(2012) Iryna Monastyrska et al.   Autophagy

Role of host reticulon proteins in rearranging membranes for positive-strand RNA virus replication

(2012) Arturo Diaz et al.   CURRENT OPINION IN MICROBIOLOGY

Viral and host factors that contribute to pathogenicity of enterovirus 71

(2012) Hsing-I Huang et al.   Future Microbiology

Live Cell Imaging of Protein Dislocation from the Endoplasmic Reticulum

(2012) Yongwang Zhong et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Cleavage of Interferon Regulatory Factor 7 by Enterovirus 71 3C Suppresses Cellular Responses

(2012) Xiaobo Lei et al.   JOURNAL OF VIROLOGY

Enterovirus 71 Disrupts Interferon Signaling by Reducing the Level of Interferon Receptor 1

(2012) J. Lu et al.   JOURNAL OF VIROLOGY

Valosin-Containing Protein (VCP/p97) Is Required for Poliovirus Replication and Is Involved in Cellular Protein Secretion Pathway in Poliovirus Infection

(2012) M. Arita et al.   JOURNAL OF VIROLOGY

Unassembled CD147 is an endogenous endoplasmic reticulum–associated degradation substrate

(2012) Ryan E. Tyler et al.   MOLECULAR BIOLOGY OF THE CELL

Triggering Fbw7-Mediated Proteasomal Degradation of c-Myc by Oridonin Induces Cell Growth Inhibition and Apoptosis

(2012) H.-L. Huang et al.   MOLECULAR CANCER THERAPEUTICS

STT3B-Dependent Posttranslational N-Glycosylation as a Surveillance System for Secretory Protein

(2012) Takashi Sato et al.   MOLECULAR CELL

The Delicate Balance Between Secreted Protein Folding and Endoplasmic Reticulum-Associated Degradation in Human Physiology

(2012) Christopher J. Guerriero et al.   PHYSIOLOGICAL REVIEWS

Activation of ERAD Pathway by Human Hepatitis B Virus Modulates Viral and Subviral Particle Production

(2012) Catalin Lazar et al.   PLoS One

Phosphatidylinositol 4-kinases: hostages harnessed to build panviral replication platforms

(2012) Nihal Altan-Bonnet et al.   TRENDS IN BIOCHEMICAL SCIENCES

Protein Folding and Quality Control in the ER

(2012) K. Araki et al.   Cold Spring Harbor Perspectives in Biology

The Mammalian Endoplasmic Reticulum-Associated Degradation System

(2012) J. A. Olzmann et al.   Cold Spring Harbor Perspectives in Biology

(+)RNA viruses rewire cellular pathways to build replication organelles

(2012) George A Belov et al.   Current Opinion in Virology

SEL1L Protein Critically Determines the Stability of the HRD1-SEL1L Endoplasmic Reticulum-associated Degradation (ERAD) Complex to Optimize the Degradation Kinetics of ERAD Substrates

(2011) Yasutaka Iida et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Role of the Endoplasmic Reticulum-associated Degradation (ERAD) Pathway in Degradation of Hepatitis C Virus Envelope Proteins and Production of Virus Particles

(2011) Mohsan Saeed et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Multifaceted Poliovirus 2A Protease: Regulation of Gene Expression by Picornavirus Proteases

(2011) Alfredo Castelló et al.   JOURNAL OF BIOMEDICINE AND BIOTECHNOLOGY

Processing and turnover of the Hedgehog protein in the endoplasmic reticulum

(2011) Xin Chen et al.   JOURNAL OF CELL BIOLOGY

Crystal Structure of Human Enterovirus 71 3C Protease

(2011) Sheng Cui et al.   JOURNAL OF MOLECULAR BIOLOGY

Cleavage of the Adaptor Protein TRIF by Enterovirus 71 3C Inhibits Antiviral Responses Mediated by Toll-Like Receptor 3

(2011) X. Lei et al.   JOURNAL OF VIROLOGY

Ultrastructural Characterization of Arterivirus Replication Structures: Reshaping the Endoplasmic Reticulum To Accommodate Viral RNA Synthesis

(2011) K. Knoops et al.   JOURNAL OF VIROLOGY

Crystal Structures of Enterovirus 71 3C Protease Complexed with Rupintrivir Reveal the Roles of Catalytically Important Residues

(2011) J. Wang et al.   JOURNAL OF VIROLOGY

Reversible inhibitor of p97, DBeQ, impairs both ubiquitin-dependent and autophagic protein clearance pathways

(2011) T.-F. Chou et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

HRD1 and UBE2J1 target misfolded MHC class I heavy chains for endoplasmic reticulum-associated degradation

(2011) Marian L. Burr et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Road to Ruin: Targeting Proteins for Degradation in the Endoplasmic Reticulum

(2011) M. H. Smith et al.   SCIENCE

Protein quality control in the ER: balancing the ubiquitin checkbook

(2011) Jasper H.L. Claessen et al.   TRENDS IN CELL BIOLOGY

The Transformation of Enterovirus Replication Structures: a Three-Dimensional Study of Single- and Double-Membrane Compartments

(2011) R. W. A. L. Limpens et al.   mBio

Autophagosome Formation and Molecular Mechanism of Autophagy

(2010) Isei Tanida   ANTIOXIDANTS & REDOX SIGNALING

Autophagy-independent LC3 function in vesicular traffic

(2010) Cornelis A.M. de Haan et al.   Autophagy

Viral Reorganization of the Secretory Pathway Generates Distinct Organelles for RNA Replication

(2010) Nai-Yun Hsu et al.   CELL

Viruses and the autophagy machinery

(2010) Marlène Dreux et al.   CELL CYCLE

Coronaviruses Hijack the LC3-I-Positive EDEMosomes, ER-Derived Vesicles Exporting Short-Lived ERAD Regulators, for Replication

(2010) Fulvio Reggiori et al.   Cell Host & Microbe

ERAD and ERAD tuning: disposal of cargo and of ERAD regulators from the mammalian ER

(2010) Riccardo Bernasconi et al.   CURRENT OPINION IN CELL BIOLOGY

Herp Regulates Hrd1-mediated Ubiquitylation in a Ubiquitin-like Domain-dependent Manner

(2010) Melanie Kny et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The 3C Protein of Enterovirus 71 Inhibits Retinoid Acid-Inducible Gene I-Mediated Interferon Regulatory Factor 3 Activation and Type I Interferon Responses

(2010) X. Lei et al.   JOURNAL OF VIROLOGY

Virology, epidemiology, pathogenesis, and control of enterovirus 71

(2010) Tom Solomon et al.   LANCET INFECTIOUS DISEASES

Autophagy in viral replication and pathogenesis

(2010) Donna Sir et al.   MOLECULES AND CELLS

An emerging recombinant human enterovirus 71 responsible for the 2008 outbreak of Hand Foot and Mouth Disease in Fuyang city of China

(2010) Yan Zhang et al.   Virology Journal

Making of Viral Replication Organelles by Remodeling Interior Membranes

(2010) Zsuzsanna Sasvari et al.   Viruses-Basel

Autophagy, antiviral immunity, and viral countermeasures

(2009) Sanae Shoji-Kawata et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

The Endoplasmic Reticulum-associated Degradation of Transthyretin Variants Is Negatively Regulated by BiP in Mammalian Cells

(2009) Seiko Susuki et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Enterovirus 71-induced autophagy detected in vitro and in vivo promotes viral replication

(2009) Shu-Chen Huang et al.   JOURNAL OF MEDICAL VIROLOGY

Life and death of a BiP substrate

(2009) Joel H. Otero et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Enterovirus 71 3C Protease Cleaves a Novel Target CstF-64 and Inhibits Cellular Polyadenylation

(2009) Kuo-Feng Weng et al.   PLoS Pathogens

One step at a time: endoplasmic reticulum-associated degradation

(2008) Shruthi S. Vembar et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

SEL1L nucleates a protein complex required for dislocation of misfolded glycoproteins

(2008) B. Mueller et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA