Salmonella exploits the host endolysosomal tethering factor HOPS complex to promote its intravacuolar replication

The Rab7 effector PLEKHM1 binds Arl8b to promote cargo traffic to lysosomes

(2017) Rituraj Marwaha et al.   JOURNAL OF CELL BIOLOGY

Receptor-Mediated Sorting of Typhoid Toxin during Its Export from Salmonella Typhi-Infected Cells

(2016) Shu-Jung Chang et al.   Cell Host & Microbe

The position of lysosomes within the cell determines their luminal pH

(2016) Danielle E. Johnson et al.   JOURNAL OF CELL BIOLOGY

CATCHR, HOPS and CORVET tethering complexes share a similar architecture

(2016) Hui-Ting Chou et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Typhoid toxin provides a window into typhoid fever and the biology ofSalmonellaTyphi

(2016) Jorge E. Galán   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cholesterol and ORP1L-mediated ER contact sites control autophagosome transport and fusion with the endocytic pathway

(2016) Ruud H. Wijdeven et al.   Nature Communications

CATCHR, HOPS and CORVET tethering complexes share a similar architecture

(2016) Hui-Ting Chou et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

The endoplasmic reticulum, not the pH gradient, drives calcium refilling of lysosomes

(2016) Abigail G Garrity et al.   eLife

PLEKHM1 Regulates Salmonella-Containing Vacuole Biogenesis and Infection

(2015) David G. McEwan et al.   Cell Host & Microbe

The COPII complex and lysosomal VAMP7 determine intracellularSalmonellalocalization and growth

(2015) José Carlos Santos et al.   CELLULAR MICROBIOLOGY

Take the tube: remodelling of the endosomal system by intracellularSalmonella enterica

(2015) Viktoria Liss et al.   CELLULAR MICROBIOLOGY

Role of Host Cell-Derived Amino Acids in Nutrition of Intracellular Salmonella enterica

(2015) Jasmin Popp et al.   INFECTION AND IMMUNITY

The small GTPase Arl8b regulates assembly of the mammalian HOPS complex on lysosomes

(2015) D. Khatter et al.   JOURNAL OF CELL SCIENCE

PLEKHM1 Regulates Autophagosome-Lysosome Fusion through HOPS Complex and LC3/GABARAP Proteins

(2015) David G. McEwan et al.   MOLECULAR CELL

Salmonellae interactions with host processes

(2015) Doris L. LaRock et al.   NATURE REVIEWS MICROBIOLOGY

Autophagosome–lysosome fusion is independent of V-ATPase-mediated acidification

(2015) Caroline Mauvezin et al.   Nature Communications

The Salmonella effector protein SifA plays a dual role in virulence

(2015) Weidong Zhao et al.   Scientific Reports

Salmonella Disrupts Host Endocytic Trafficking by SopD2-Mediated Inhibition of Rab7

(2015) Vanessa M. D’Costa et al.   Cell Reports

TRAFD1 (FLN29) Interacts with Plekhm1 and Regulates Osteoclast Acidification and Resorption

(2015) Hanna Witwicka et al.   PLoS One

Proteomes of Host Cell Membranes Modified by Intracellular Activities ofSalmonella enterica

(2014) Stephanie Vorwerk et al.   MOLECULAR & CELLULAR PROTEOMICS

The HOPS complex mediates autophagosome–lysosome fusion through interaction with syntaxin 17

(2014) Peidu Jiang et al.   MOLECULAR BIOLOGY OF THE CELL

Quantitative Assessment of Cytosolic Salmonella in Epithelial Cells

(2014) Leigh A. Knodler et al.   PLoS One

Live Cell Imaging Reveals Novel Functions of Salmonella enterica SPI2-T3SS Effector Proteins in Remodeling of the Host Cell Endosomal System

(2014) Roopa Rajashekar et al.   PLoS One

Mammalian CORVET Is Required for Fusion and Conversion of Distinct Early Endosome Subpopulations

(2014) Enrico D. Perini et al.   TRAFFIC

Reorganization of the Endosomal System in Salmonella-Infected Cells: The Ultrastructure of Salmonella-Induced Tubular Compartments

(2014) Viktoria Krieger et al.   PLoS Pathogens

Tethering complexes in the endocytic pathway: CORVET and HOPS

(2013) Jachen A. Solinger et al.   FEBS Journal

Late endosomal transport and tethering are coupled processes controlled by RILP and the cholesterol sensor ORP1L

(2013) R. van der Kant et al.   JOURNAL OF CELL SCIENCE

CORVET and HOPS tethering complexes - coordinators of endosome and lysosome fusion

(2013) H. J. k. Balderhaar et al.   JOURNAL OF CELL SCIENCE

Arl8/ARL-8 functions in apoptotic cell removal by mediating phagolysosome formation in Caenorhabditis elegans

(2013) Ayaka Sasaki et al.   MOLECULAR BIOLOGY OF THE CELL

The CORVET complex promotes tethering and fusion of Rab5/Vps21-positive membranes

(2013) H. J. k. Balderhaar et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Impaired Stimulation of p38α-MAPK/Vps41-HOPS by LPS from Pathogenic Coxiella burnetii Prevents Trafficking to Microbicidal Phagolysosomes

(2012) Abdoulaye Oury Barry et al.   Cell Host & Microbe

Functions of the Salmonella pathogenicity island 2 (SPI-2) type III secretion system effectors

(2012) R. Figueira et al.   MICROBIOLOGY-SGM

The Bimodal Lifestyle of Intracellular Salmonella in Epithelial Cells: Replication in the Cytosol Obscures Defects in Vacuolar Replication

(2012) Preeti Malik-Kale et al.   PLoS One

Salmonella Inhibits Retrograde Trafficking of Mannose-6-Phosphate Receptors and Lysosome Function

(2012) K. McGourty et al.   SCIENCE

The HOPS Proteins hVps41 and hVps39 Are Required for Homotypic and Heterotypic Late Endosome Fusion

(2012) Maaike S. Pols et al.   TRAFFIC

Salmonella exploits Arl8B-directed kinesin activity to promote endosome tubulation and cell-to-cell transfer

(2011) Natalia A. Kaniuk et al.   CELLULAR MICROBIOLOGY

Arl8 and SKIP Act Together to Link Lysosomes to Kinesin-1

(2011) Cláudia Rosa-Ferreira et al.   DEVELOPMENTAL CELL

Lysosomal Trafficking, Antigen Presentation, and Microbial Killing Are Controlled by the Arf-like GTPase Arl8b

(2011) Salil Garg et al.   IMMUNITY

Ebola virus entry requires the cholesterol transporter Niemann–Pick C1

(2011) Jan E. Carette et al.   NATURE

Monitoring of Gene Expression in Bacteria during Infections Using an Adaptable Set of Bioluminescent, Fluorescent and Colorigenic Fusion Vectors

(2011) Frank Uliczka et al.   PLoS One

Proteolytic targeting of Rab29 by an effector protein distinguishes the intracellular compartments of human-adapted and broad-host Salmonella

(2011) S. Spano et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Kinesin regulation by Salmonella

(2011) Philippe Leone et al.   Virulence

Identification of the Switch in Early-to-Late Endosome Transition

(2010) Dmitry Poteryaev et al.   CELL

The Phosphoinositide Phosphatase SopB Manipulates Membrane Surface Charge and Trafficking of the Salmonella-Containing Vacuole

(2010) Malina A. Bakowski et al.   Cell Host & Microbe

Identification of two evolutionarily conserved genes regulating processing of engulfed apoptotic cells

(2010) Jason M. Kinchen et al.   NATURE

pH Sensing by Intracellular Salmonella Induces Effector Translocation

(2010) X. J. Yu et al.   SCIENCE

SKIP, the Host Target of the Salmonella Virulence Factor SifA, Promotes Kinesin-1-Dependent Vacuolar Membrane Exchanges

(2010) Audrey Dumont et al.   TRAFFIC

Vps41 Phosphorylation and the Rab Ypt7 Control the Targeting of the HOPS Complex to Endosome–Vacuole Fusion Sites

(2009) Margarita Cabrera et al.   MOLECULAR BIOLOGY OF THE CELL

Delivery of a Salmonella Typhi Exotoxin from a Host Intracellular Compartment

(2008) Stefania Spanò et al.   Cell Host & Microbe

Structure and Function of Salmonella SifA Indicate that Its Interactions with SKIP, SseJ, and RhoA Family GTPases Induce Endosomal Tubulation

(2008) Maikke B. Ohlson et al.   Cell Host & Microbe

SopB promotes phosphatidylinositol 3-phosphate formation onSalmonellavacuoles by recruiting Rab5 and Vps34

(2008) Gustavo V. Mallo et al.   JOURNAL OF CELL BIOLOGY

Sorting nexin-1 defines an early phase of Salmonella-containing vacuole-remodeling during Salmonella infection

(2008) M. V. Bujny et al.   JOURNAL OF CELL SCIENCE

The Salmonella virulence protein SifA is a G protein antagonist

(2008) L. K. Jackson et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Dynamic Behavior ofSalmonella-Induced Membrane Tubules in Epithelial Cells

(2008) Dan Drecktrah et al.   TRAFFIC

Dynamic Remodeling of the Endosomal System During Formation ofSalmonella-Induced Filaments by IntracellularSalmonella enterica

(2008) Roopa Rajashekar et al.   TRAFFIC