Multi-functional mechanisms of immune evasion by the streptococcal complement inhibitor C5a peptidase

Development of a multicomponent vaccine for Streptococcus pyogenes based on the antigenic targets of IVIG

(2016) Mark Reglinski et al.   JOURNAL OF INFECTION

Identification of the Streptococcus pyogenes surface antigens recognised by pooled human immunoglobulin

(2015) Mark Reglinski et al.   Scientific Reports

Rapid Lymphatic Dissemination of Encapsulated Group A Streptococci via Lymphatic Vessel Endothelial Receptor-1 Interaction

(2015) Nicola N. Lynskey et al.   PLoS Pathogens

Immune Evasion of Enterococcus faecalis by an Extracellular Gelatinase That Cleaves C3 and iC3b

(2014) S. Y. Park et al.   JOURNAL OF IMMUNOLOGY

A Systematic and Functional Classification of Streptococcus pyogenes That Serves as a New Tool for Molecular Typing and Vaccine Development

(2014) Martina Sanderson-Smith et al.   JOURNAL OF INFECTIOUS DISEASES

Binding of Complement Inhibitor C4b-binding Protein to a Highly VirulentStreptococcus pyogenesM1 Strain Is Mediated by Protein H and Enhances Adhesion to and Invasion of Endothelial Cells

(2013) David Ermert et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Cysteine Proteinase fromStreptococcus pyogenesEnables Evasion of Innate Immunity via Degradation of Complement Factors

(2013) Mariko Honda-Ogawa et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Molecular Analysis of an Outbreak of Lethal Postpartum Sepsis Caused by Streptococcus pyogenes

(2013) C. E. Turner et al.   JOURNAL OF CLINICAL MICROBIOLOGY

Staphylococcal Proteases Aid in Evasion of the Human Complement System

(2013) Monika Jusko et al.   Journal of Innate Immunity

Neisseria meningitidis NalP cleaves human complement C3, facilitating degradation of C3b and survival in human serum

(2013) E. Del Tordello et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

RocA Truncation Underpins Hyper-Encapsulation, Carriage Longevity and Transmissibility of Serotype M18 Group A Streptococci

(2013) Nicola N. Lynskey et al.   PLoS Pathogens

Streptococcus pneumoniae Capsular Serotype Invasiveness Correlates with the Degree of Factor H Binding and Opsonization with C3b/iC3b

(2012) Catherine Hyams et al.   INFECTION AND IMMUNITY

Enolase of Streptococcus pneumoniae Binds Human Complement Inhibitor C4b-Binding Protein and Contributes to Complement Evasion

(2012) V. Agarwal et al.   JOURNAL OF IMMUNOLOGY

Human C3a and C3a desArg anaphylatoxins have conserved structures, in contrast to C5a and C5a desArg

(2012) Goran Bajic et al.   PROTEIN SCIENCE

Staphylococcus aureus Metalloprotease Aureolysin Cleaves Complement C3 To Mediate Immune Evasion

(2011) A. J. Laarman et al.   JOURNAL OF IMMUNOLOGY

Clumping Factor A Interaction with Complement Factor I Increases C3b Cleavage on the Bacterial Surface of Staphylococcus aureus and Decreases Complement-Mediated Phagocytosis

(2010) P. S. Hair et al.   INFECTION AND IMMUNITY

Chemokine-cleaving Streptococcus pyogenes protease SpyCEP is necessary and sufficient for bacterial dissemination within soft tissues and the respiratory tract

(2010) Prathiba Kurupati et al.   MOLECULAR MICROBIOLOGY

Emerging Role of the Interleukin‐8 Cleaving Enzyme SpyCEP in ClinicalStreptococcus pyogenesInfection

(2009) Claire E. Turner et al.   JOURNAL OF INFECTIOUS DISEASES

Model for Substrate Interactions in C5a Peptidase from Streptococcus pyogenes: A 1.9 Å Crystal Structure of the Active Form of ScpA

(2009) Todd F. Kagawa et al.   JOURNAL OF MOLECULAR BIOLOGY

Genomic Evidence for the Evolution of Streptococcus equi: Host Restriction, Increased Virulence, and Genetic Exchange with Human Pathogens

(2009) Matthew T. G. Holden et al.   PLoS Pathogens

Comprehensive analysis of antibody responses to streptococcal and tissue antigens in patients with acute rheumatic fever

(2008) T. B. Martins et al.   INTERNATIONAL IMMUNOLOGY