Blocking two-component signalling enhances Candida albicans virulence and reveals adaptive mechanisms that counteract sustained SAPK activation

Interactions of fungal pathogens with phagocytes

(2016) Lars P. Erwig et al.   NATURE REVIEWS MICROBIOLOGY

A Case for Two-Component Signaling Systems As Antifungal Drug Targets

(2015) Erika Shor et al.   PLoS Pathogens

Two-Component Histidine Phosphotransfer Protein Ypd1 Is Not Essential for Viability in Candida albicans

(2014) John Mavrianos et al.   EUKARYOTIC CELL

Distinct and Redundant Roles of Protein Tyrosine Phosphatases Ptp1 and Ptp2 in Governing the Differentiation and Pathogenicity of Cryptococcus neoformans

(2014) Kyung-Tae Lee et al.   EUKARYOTIC CELL

The HOG Pathway Is Critical for the Colonization of the Mouse Gastrointestinal Tract by Candida albicans

(2014) Daniel Prieto et al.   PLoS One

New Clox Systems for Rapid and Efficient Gene Disruption in Candida albicans

(2014) Shahida Shahana et al.   PLoS One

The Pathogen Candida albicans Hijacks Pyroptosis for Escape from Macrophages

(2014) N. Uwamahoro et al.   mBio

Histidine Phosphotransfer Proteins in Fungal Two-Component Signal Transduction Pathways

(2013) Jan S. Fassler et al.   EUKARYOTIC CELL

Stress adaptation in a pathogenic fungus

(2013) A. J. P. Brown et al.   JOURNAL OF EXPERIMENTAL BIOLOGY

Candida albicanspathogenicity mechanisms

(2013) François L. Mayer et al.   Virulence

Response to Hyperosmotic Stress

(2012) H. Saito et al.   GENETICS

Reduced TOR signaling sustains hyphal development in Candida albicans by lowering Hog1 basal activity

(2012) Chang Su et al.   MOLECULAR BIOLOGY OF THE CELL

Mammalian MAPK Signal Transduction Pathways Activated by Stress and Inflammation: A 10-Year Update

(2012) John M. Kyriakis et al.   PHYSIOLOGICAL REVIEWS

Response to Arsenate Treatment in Schizosaccharomyces pombe and the Role of Its Arsenate Reductase Activity

(2012) Alejandro Salgado et al.   PLoS One

Hidden Killers: Human Fungal Infections

(2012) G. D. Brown et al.   Science Translational Medicine

Mechanisms underlying the inhibitory effects of arsenic compounds on protein tyrosine phosphatase (PTP)

(2012) Kanwal Rehman et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Stage Specific Assessment of Candida albicans Phagocytosis by Macrophages Identifies Cell Wall Composition and Morphogenesis as Key Determinants

(2012) Leanne E. Lewis et al.   PLoS Pathogens

Oxidative stress-induced formation of a positive-feedback loop for the sustained activation of p38 MAPK leading to the loss of cell division in cardiomyocytes soon after birth

(2011) Daisuke Matsuyama et al.   BASIC RESEARCH IN CARDIOLOGY

Sir2 histone deacetylase prevents programmed cell death caused by sustained activation of the Hog1 stress-activated protein kinase

(2011) Alexandre Vendrell et al.   EMBO REPORTS

Multiple Roles of Ypd1 Phosphotransfer Protein in Viability, Stress Response, and Virulence Factor Regulation in Cryptococcus neoformans

(2011) Jang-Won Lee et al.   EUKARYOTIC CELL

Candida albicans SRR1 , a Putative Two-Component Response Regulator Gene, Is Required for Stress Adaptation, Morphogenesis, and Virulence

(2011) Chirayu Desai et al.   EUKARYOTIC CELL

MAPKKK-independent Regulation of the Hog1 Stress-activated Protein Kinase inCandida albicans

(2011) Jill Cheetham et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Identification of a Novel Response Regulator, Crr1, That Is Required for Hydrogen Peroxide Resistance in Candida albicans

(2011) Catherine R. Bruce et al.   PLoS One

Genetic Dissection of Azole Resistance Mechanisms in Candida albicans and Their Validation in a Mouse Model of Disseminated Infection

(2010) D. M. MacCallum et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Whole genome analysis of p38 SAPK-mediated gene expression upon stress

(2010) Isabel Ferreiro et al.   BMC GENOMICS

Histidine kinases keep fungi safe and vigorous

(2010) Dongmei Li et al.   CURRENT OPINION IN MICROBIOLOGY

Stress signalling to fungal stress-activated protein kinase pathways

(2010) Deborah A. Smith et al.   FEMS MICROBIOLOGY LETTERS

Contribution of Candida albicans Cell Wall Components to Recognition by and Escape from Murine Macrophages

(2010) C. G. J. McKenzie et al.   INFECTION AND IMMUNITY

Abrogation of NF-κB signaling in human neutrophils induces neutrophil survival through sustained p38-MAPK activation

(2010) Jeroen D. Langereis et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Phylogenetic diversity of stress signaling pathways in fungi

(2009) Elissavet Nikolaou et al.   BMC EVOLUTIONARY BIOLOGY

Candida albicansHyphal Formation and Virulence Assessed Using aCaenorhabditis elegansInfection Model

(2009) Read Pukkila-Worley et al.   EUKARYOTIC CELL

Property Differences among the Four MajorCandida albicansStrain Clades

(2009) Donna M. MacCallum et al.   EUKARYOTIC CELL

Phosphorylated Ssk1 Prevents Unphosphorylated Ssk1 from Activating the Ssk2 Mitogen-Activated Protein Kinase Kinase Kinase in the Yeast High-Osmolarity Glycerol Osmoregulatory Pathway

(2008) T. Horie et al.   MOLECULAR AND CELLULAR BIOLOGY

Expression levels of a filament-specific transcriptional regulator are sufficient to determine Candida albicans morphology and virulence

(2008) P. L. Carlisle et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA