A novel genetic technique in Plasmodium berghei allows liver stage analysis of genes required for mosquito stage development and demonstrates that de novo heme synthesis is essential for liver stage development in the malaria parasite

Distinct Prominent Roles for Enzymes of Plasmodium berghei Heme Biosynthesis in Sporozoite and Liver Stage Maturation

(2016) Zaira Rizopoulos et al.   INFECTION AND IMMUNITY

Apicomplexan Energy Metabolism: Carbon Source Promiscuity and the Quiescence Hyperbole

(2016) Damien Jacot et al.   TRENDS IN PARASITOLOGY

ThePlasmodiumtranslocon of exported proteins component EXP2 is critical for establishing a patent malaria infection in mice

(2015) Ming Kalanon et al.   CELLULAR MICROBIOLOGY

Advances in molecular genetic systems in malaria

(2015) Tania F. de Koning-Ward et al.   NATURE REVIEWS MICROBIOLOGY

Mitochondrial ATP synthase is dispensable in blood-stagePlasmodium bergheirodent malaria but essential in the mosquito phase

(2015) Angelika Sturm et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Deconvoluting heme biosynthesis to target blood-stage malaria parasites

(2015) Paul A Sigala et al.   eLife

The Peculiarities and Paradoxes of Plasmodium Heme Metabolism

(2014) Paul A. Sigala et al.   Annual Review of Microbiology

Red cells from ferrochelatase-deficient erythropoietic protoporphyria patients are resistant to growth of malarial parasites

(2014) C. M. Smith et al.   BLOOD

The Heme Biosynthesis Pathway Is Essential forPlasmodium falciparumDevelopment in Mosquito Stage but Not in Blood Stages

(2014) Hangjun Ke et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A key role for lipoic acid synthesis duringPlasmodiumliver stage development

(2013) Brie Falkard et al.   CELLULAR MICROBIOLOGY

The Malarial Serine Protease SUB1 Plays an Essential Role in Parasite Liver Stage Development

(2013) Catherine Suarez et al.   PLoS Pathogens

Malaria Parasite-Synthesized Heme Is Essential in the Mosquito and Liver Stages and Complements Host Heme in the Blood Stages of Infection

(2013) Viswanathan Arun Nagaraj et al.   PLoS Pathogens

Expansion of experimental genetics approaches for Plasmodium berghei with versatile transfection vectors

(2012) Taco W.A. Kooij et al.   MOLECULAR AND BIOCHEMICAL PARASITOLOGY

Site-specific genome editing in Plasmodium falciparum using engineered zinc-finger nucleases

(2012) Judith Straimer et al.   NATURE METHODS

Assessing the adequacy of attenuation of genetically modified malaria parasite vaccine candidates

(2012) Takeshi Annoura et al.   VACCINE

Superior Antimalarial Immunity after Vaccination with Late Liver Stage-Arresting Genetically Attenuated Parasites

(2011) Noah S. Butler et al.   Cell Host & Microbe

In vitro culture of Plasmodium berghei-ANKA maintains infectivity of mouse erythrocytes inducing cerebral malaria

(2011) Ronan Jambou et al.   MALARIA JOURNAL

FLP/FRT-mediated conditional mutagenesis in pre-erythrocytic stages of Plasmodium berghei

(2011) Céline Lacroix et al.   Nature Protocols

A toolbox to study liver stage malaria

(2011) Miguel Prudêncio et al.   TRENDS IN PARASITOLOGY

Clonal Conditional Mutagenesis in Malaria Parasites

(2009) Audrey Combe et al.   Cell Host & Microbe

The Fatty Acid Biosynthesis Enzyme FabI Plays a Key Role in the Development of Liver-Stage Malarial Parasites

(2008) Min Yu et al.   Cell Host & Microbe

TREP, a novel protein necessary for gliding motility of the malaria sporozoite

(2008) Audrey Combe et al.   INTERNATIONAL JOURNAL FOR PARASITOLOGY

Alteration of the Parasite Plasma Membrane and the Parasitophorous Vacuole Membrane during Exo-Erythrocytic Development of Malaria Parasites

(2008) Angelika Sturm et al.   PROTIST