Discovery by organism based high-throughput screening of new multi-stage compounds affecting Schistosoma mansoni viability, egg formation and production

Arylmethylamino steroids as antiparasitic agents

(2017) Reimar Krieg et al.   Nature Communications

Derivatives of biarylalkyl carboxylic acid induce pleiotropic phenotypes in adult Schistosoma mansoni in vitro

(2016) Ariane S. Blohm et al.   PARASITOLOGY RESEARCH

Discovery and Characterization of Novel Anti-schistosomal Properties of the Anti-anginal Drug, Perhexiline and Its Impact on Schistosoma mansoni Male and Female Reproductive Systems

(2016) Alessandra Guidi et al.   PLoS Neglected Tropical Diseases

Development and Validation of a Luminescence-based, Medium-Throughput Assay for Drug Screening in Schistosoma mansoni

(2015) Cristiana Lalli et al.   PLoS Neglected Tropical Diseases

Schistosoma mansoni: a method for inducing resistance to praziquantel using infected Biomphalaria glabrata snails

(2014) Flávia FB Couto et al.   MEMORIAS DO INSTITUTO OSWALDO CRUZ

Schistosomiasis control: praziquantel forever?

(2014) Donato Cioli et al.   MOLECULAR AND BIOCHEMICAL PARASITOLOGY

Epigenetic Changes Modulate Schistosome Egg Formation and Are a Novel Target for Reducing Transmission of Schistosomiasis

(2014) Vitor Coutinho Carneiro et al.   PLoS Pathogens

Praziquantel sensitivity of Kenyan Schistosoma mansoni isolates and the generation of a laboratory strain with reduced susceptibility to the drug

(2014) Ibrahim N. Mwangi et al.   International Journal for Parasitology-Drugs and Drug Resistance

Mefloquine, a new type of compound against schistosomes and other helminthes in experimental studies

(2013) Shu-hua Xiao   PARASITOLOGY RESEARCH

Comparative Study of Transcriptome Profiles of Mechanical- and Skin-Transformed Schistosoma mansoni Schistosomula

(2013) Anna V. Protasio et al.   PLoS Neglected Tropical Diseases

Characterization of the cGMP-dependent protein kinase SmcGK1 of Schistosoma mansoni

(2011) Silke Leutner et al.   ANAIS DA ACADEMIA BRASILEIRA DE CIENCIAS

Pharmacophore Modelling: A Forty Year Old Approach and its Modern Synergies

(2011) F. Caporuscio et al.   CURRENT MEDICINAL CHEMISTRY

Schistosoma mansoni: The egg, biosynthesis of the shell and interaction with the host

(2011) Saskia deWalick et al.   EXPERIMENTAL PARASITOLOGY

Imatinib has a fatal impact on morphology, pairing stability and survival of adult Schistosoma mansoni in vitro

(2010) S. Beckmann et al.   INTERNATIONAL JOURNAL FOR PARASITOLOGY

The Syk Kinase SmTK4 of Schistosoma mansoni Is Involved in the Regulation of Spermatogenesis and Oogenesis

(2010) Svenja Beckmann et al.   PLoS Pathogens

Morphological effects and tegumental alterations induced by mefloquine on schistosomula and adult flukes of Schistosoma mansoni

(2009) T. MANNECK et al.   PARASITOLOGY

Reduced Susceptibility to Praziquantel among Naturally Occurring Kenyan Isolates of Schistosoma mansoni

(2009) Sandra D. Melman et al.   PLoS Neglected Tropical Diseases

Praziquantel: mechanisms of action, resistance and new derivatives for schistosomiasis

(2008) Michael J Doenhoff et al.   CURRENT OPINION IN INFECTIOUS DISEASES

Pharao: Pharmacophore alignment and optimization

(2008) Jonatan Taminau et al.   JOURNAL OF MOLECULAR GRAPHICS & MODELLING

Response of Schistosoma mansoni Isolates Having Different Drug Sensitivity to Praziquantel Over Several Life Cycle Passages with and Without Therapeutic Pressure

(2008) Abdel Nasser A. Sabra et al.   JOURNAL OF PARASITOLOGY

Towards an understanding of the mechanism of action of praziquantel

(2008) Anthony D. Aragon et al.   MOLECULAR AND BIOCHEMICAL PARASITOLOGY