Using Genetic Variation to Explore the Causal Effect of Maternal Pregnancy Adiposity on Future Offspring Adiposity: A Mendelian Randomisation Study
Published 2017 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Using Genetic Variation to Explore the Causal Effect of Maternal Pregnancy Adiposity on Future Offspring Adiposity: A Mendelian Randomisation Study
Authors
Keywords
Pregnancy, Alleles, Genome-wide association studies, Body mass index, Fats, Obesity, Meta-analysis, Human genetics
Journal
PLOS MEDICINE
Volume 14, Issue 1, Pages e1002221
Publisher
Public Library of Science (PLoS)
Online
2017-01-25
DOI
10.1371/journal.pmed.1002221
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Challenges in conducting genome-wide association studies in highly admixed multi-ethnic populations: the Generation R Study
- (2015) Carolina Medina-Gomez et al. EUROPEAN JOURNAL OF EPIDEMIOLOGY
- A genome-wide association study of body mass index across early life and childhood
- (2015) N. M. Warrington et al. INTERNATIONAL JOURNAL OF EPIDEMIOLOGY
- Mendelian randomization with invalid instruments: effect estimation and bias detection through Egger regression
- (2015) J. Bowden et al. INTERNATIONAL JOURNAL OF EPIDEMIOLOGY
- Genetic studies of body mass index yield new insights for obesity biology
- (2015) Adam E. Locke et al. NATURE
- Detecting pleiotropy in Mendelian randomisation studies with summary data and a continuous outcome
- (2015) Fabiola Del Greco M et al. STATISTICS IN MEDICINE
- Assessing the Causal Relationship of Maternal Height on Birth Size and Gestational Age at Birth: A Mendelian Randomization Analysis
- (2015) Ge Zhang et al. PLOS MEDICINE
- Childhood consequences of maternal obesity and excessive weight gain during pregnancy
- (2014) Romy Gaillard et al. ACTA OBSTETRICIA ET GYNECOLOGICA SCANDINAVICA
- The Generation R Study: Biobank update 2015
- (2014) Claudia J. Kruithof et al. EUROPEAN JOURNAL OF EPIDEMIOLOGY
- Mendelian randomization: genetic anchors for causal inference in epidemiological studies
- (2014) G. Davey Smith et al. HUMAN MOLECULAR GENETICS
- Testing for non-linear causal effects using a binary genotype in a Mendelian randomization study: application to alcohol and cardiovascular traits
- (2014) Richard J Silverwood et al. INTERNATIONAL JOURNAL OF EPIDEMIOLOGY
- Society: Don't blame the mothers
- (2014) Sarah S. Richardson et al. NATURE
- Phenotypic Dissection of Bone Mineral Density Reveals Skeletal Site Specificity and Facilitates the Identification of Novel Loci in the Genetic Regulation of Bone Mass Attainment
- (2014) John P. Kemp et al. PLoS Genetics
- Metabolic Signatures of Adiposity in Young Adults: Mendelian Randomization Analysis and Effects of Weight Change
- (2014) Peter Würtz et al. PLOS MEDICINE
- Maternal and Paternal Body Mass Index and Offspring Obesity: A Systematic Review
- (2013) Bernadeta Patro et al. ANNALS OF NUTRITION AND METABOLISM
- Genome-wide association study identifies loci affecting blood copper, selenium and zinc
- (2013) David M. Evans et al. HUMAN MOLECULAR GENETICS
- Childhood Cardiometabolic Outcomes of Maternal Obesity During Pregnancy
- (2013) Romy Gaillard et al. HYPERTENSION
- Comparison of father-offspring and mother-offspring associations of cardiovascular risk factors: family linkage within the population-based HUNT Study, Norway
- (2013) Kirsti L Vik et al. INTERNATIONAL JOURNAL OF EPIDEMIOLOGY
- The Society for Social Medicine John Pemberton Lecture 2011. Developmental overnutrition—an old hypothesis with new importance?*
- (2013) Debbie A Lawlor INTERNATIONAL JOURNAL OF EPIDEMIOLOGY
- Use of allele scores as instrumental variables for Mendelian randomization
- (2013) Stephen Burgess et al. INTERNATIONAL JOURNAL OF EPIDEMIOLOGY
- Risk factors and outcomes of maternal obesity and excessive weight gain during pregnancy
- (2013) Romy Gaillard et al. Obesity
- Pre-Pregnancy Body Mass Index in Relation to Infant Birth Weight and Offspring Overweight/Obesity: A Systematic Review and Meta-Analysis
- (2013) Zhangbin Yu et al. PLoS One
- Mining the Human Phenome Using Allelic Scores That Index Biological Intermediates
- (2013) David M. Evans et al. PLoS Genetics
- Parent-Offspring Body Mass Index Associations in the Norwegian Mother and Child Cohort Study: A Family-based Approach to Studying the Role of the Intrauterine Environment in Childhood Adiposity
- (2012) C. Fleten et al. AMERICAN JOURNAL OF EPIDEMIOLOGY
- Genome-wide Association Study of Three-Dimensional Facial Morphology Identifies a Variant in PAX3 Associated with Nasion Position
- (2012) Lavinia Paternoster et al. AMERICAN JOURNAL OF HUMAN GENETICS
- The Generation R Study: design and cohort update 2012
- (2012) Vincent W. V. Jaddoe et al. EUROPEAN JOURNAL OF EPIDEMIOLOGY
- Cohort Profile: The Avon Longitudinal Study of Parents and Children: ALSPAC mothers cohort
- (2012) A. Fraser et al. INTERNATIONAL JOURNAL OF EPIDEMIOLOGY
- Cohort Profile: The ‘Children of the 90s’—the index offspring of the Avon Longitudinal Study of Parents and Children
- (2012) Andy Boyd et al. INTERNATIONAL JOURNAL OF EPIDEMIOLOGY
- Maternal adiposity—a determinant of perinatal and offspring outcomes?
- (2012) Debbie A. Lawlor et al. Nature Reviews Endocrinology
- Association of Maternal Diabetes Mellitus in Pregnancy With Offspring Adiposity Into Early Adulthood
- (2011) Debbie A. Lawlor et al. CIRCULATION
- Continuous Glucose Profiles in Obese and Normal-Weight Pregnant Women on a Controlled Diet: Metabolic determinants of fetal growth
- (2011) K. A. Harmon et al. DIABETES CARE
- Developmental Programming of Energy Balance and Its Hypothalamic Regulation
- (2011) Floor Remmers et al. ENDOCRINE REVIEWS
- Familial Associations of Adiposity: Findings from a Cross-Sectional Study of 12,181 Parental-Offspring Trios from Belarus
- (2011) Rita Patel et al. PLoS One
- Assessing Intrauterine Influences on Offspring Health Outcomes: Can Epidemiological Studies Yield Robust Findings?
- (2010) George Davey Smith BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY
- The Generation R Study: design and cohort update 2010
- (2010) Vincent W. V. Jaddoe et al. EUROPEAN JOURNAL OF EPIDEMIOLOGY
- MaCH: using sequence and genotype data to estimate haplotypes and unobserved genotypes
- (2010) Yun Li et al. GENETIC EPIDEMIOLOGY
- Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index
- (2010) Elizabeth K Speliotes et al. NATURE GENETICS
- Obesity in Pregnancy: Implications for the Mother and Lifelong Health of the Child. A Consensus Statement
- (2010) Lucilla Poston et al. PEDIATRIC RESEARCH
- Parental BMI and Childhood Undernutrition in India: An Assessment of Intrauterine Influence
- (2010) S. V. Subramanian et al. PEDIATRICS
- Intrauterine Effects of Maternal Prepregnancy Overweight on Child Cognition and Behavior in 2 Cohorts
- (2010) M.-J. Brion et al. PEDIATRICS
- Impact of maternal obesity on offspring obesity and cardiometabolic disease risk
- (2010) Amanda J Drake et al. REPRODUCTION
- Assumptions of IV Methods for Observational Epidemiology
- (2010) Vanessa Didelez et al. STATISTICAL SCIENCE
- Perinatal risk factors for childhood obesity and metabolic dysregulation
- (2009) Patrick M Catalano et al. AMERICAN JOURNAL OF CLINICAL NUTRITION
- Genotype Imputation
- (2009) Yun Li et al. Annual Review of Genomics and Human Genetics
- Risk prediction of prevalent diabetes in a Swiss population using a weighted genetic score—the CoLaus Study
- (2009) X. Lin et al. DIABETOLOGIA
- Maternal metabolism and obesity: modifiable determinants of pregnancy outcome
- (2009) S. M. Nelson et al. HUMAN REPRODUCTION UPDATE
- Effects of Maternal Surgical Weight Loss in Mothers on Intergenerational Transmission of Obesity
- (2009) J. Smith et al. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
- Severe Obesity in Young Women and Reproductive Health: The Danish National Birth Cohort
- (2009) Ellen A. Nohr et al. PLoS One
- Common Variation in the FTO Gene Alters Diabetes-Related Metabolic Traits to the Extent Expected Given Its Effect on BMI
- (2008) R. M. Freathy et al. DIABETES
- Determining Origins and Causes of Childhood Obesity via Mendelian Randomization Analysis
- (2008) Eric L Ding et al. PLOS MEDICINE
- Exploring the Developmental Overnutrition Hypothesis Using Parental–Offspring Associations and FTO as an Instrumental Variable
- (2008) Debbie A Lawlor et al. PLOS MEDICINE
- Mendelian randomization: Using genes as instruments for making causal inferences in epidemiology
- (2007) Debbie A. Lawlor et al. STATISTICS IN MEDICINE
Discover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversationCreate your own webinar
Interested in hosting your own webinar? Check the schedule and propose your idea to the Peeref Content Team.
Create Now