Genome-wide association study of red blood cell traits in Hispanics/Latinos: The Hispanic Community Health Study/Study of Latinos

A powerful statistical framework for generalization testing in GWAS, with application to the HCHS/SOL

(2017) Tamar Sofer et al.   GENETIC EPIDEMIOLOGY

Model-free Estimation of Recent Genetic Relatedness

(2016) Matthew P. Conomos et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Exome Genotyping Identifies Pleiotropic Variants Associated with Red Blood Cell Traits

(2016) Nathalie Chami et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Genetic Diversity and Association Studies in US Hispanic/Latino Populations: Applications in the Hispanic Community Health Study/Study of Latinos

(2016) Matthew P. Conomos et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Genome-wide Association Study of Platelet Count Identifies Ancestry-Specific Loci in Hispanic/Latino Americans

(2016) Ursula M. Schick et al.   AMERICAN JOURNAL OF HUMAN GENETICS

The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease

(2016) William J. Astle et al.   CELL

Discovery and refinement of genetic loci associated with cardiometabolic risk using dense imputation maps

(2016) Valentina Iotchkova et al.   NATURE GENETICS

Local Ancestry Inference in a Large US-Based Hispanic/Latino Study: Hispanic Community Health Study/Study of Latinos (HCHS/SOL)

(2016) Sharon R. Browning et al.   G3-Genes Genomes Genetics

Loss of balancing selection in the βS globin locus

(2016) Niven A Salih et al.   BMC Medical Genetics

The impact of low-frequency and rare variants on lipid levels

(2015) Ida Surakka et al.   NATURE GENETICS

Genome-wide association analyses based on whole-genome sequencing in Sardinia provide insights into regulation of hemoglobin levels

(2015) Fabrice Danjou et al.   NATURE GENETICS

A method to predict the impact of regulatory variants from DNA sequence

(2015) Dongwon Lee et al.   NATURE GENETICS

The Genotype-Tissue Expression (GTEx) pilot analysis: Multitissue gene regulation in humans

(2015) et al.   SCIENCE

Global transcriptome analyses of human and murine terminal erythroid differentiation

(2014) X. An et al.   BLOOD

Malaria parasites and red cell variants

(2014) Steve M. Taylor et al.   CURRENT OPINION IN HEMATOLOGY

Characterization of Genomic Deletion Efficiency Mediated by Clustered Regularly Interspaced Palindromic Repeats (CRISPR)/Cas9 Nuclease System in Mammalian Cells

(2014) Matthew C. Canver et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A general framework for estimating the relative pathogenicity of human genetic variants

(2014) Martin Kircher et al.   NATURE GENETICS

Functional annotation of noncoding sequence variants

(2014) Graham R S Ritchie et al.   NATURE METHODS

CODEX: a next-generation sequencing experiment database for the haematopoietic and embryonic stem cell communities

(2014) Manuel Sánchez-Castillo et al.   NUCLEIC ACIDS RESEARCH

Track data hubs enable visualization of user-defined genome-wide annotations on the UCSC Genome Browser

(2013) B. J. Raney et al.   BIOINFORMATICS

Genome-wide association analysis of red blood cell traits in African Americans: the COGENT Network

(2013) Zhao Chen et al.   HUMAN MOLECULAR GENETICS

Systematic identification of trans eQTLs as putative drivers of known disease associations

(2013) Harm-Jan Westra et al.   NATURE GENETICS

Association of Cytokine and Toll-Like Receptor Gene Polymorphisms with Severe Malaria in Three Regions of Cameroon

(2013) Tobias O. Apinjoh et al.   PLoS One

Transcription factor PROX1: its role in development and cancer

(2012) Tamador Elsir et al.   CANCER AND METASTASIS REVIEWS

Combinatorial Assembly of Developmental Stage-Specific Enhancers Controls Gene Expression Programs during Human Erythropoiesis

(2012) Jian Xu et al.   DEVELOPMENTAL CELL

Genetic and Molecular Insights Into the Role of PROX1 in Glucose Metabolism

(2012) S. Lecompte et al.   DIABETES

Annotation of functional variation in personal genomes using RegulomeDB

(2012) A. P. Boyle et al.   GENOME RESEARCH

GWAS of blood cell traits identifies novel associated loci and epistatic interactions in Caucasian and African-American children

(2012) Jin Li et al.   HUMAN MOLECULAR GENETICS

Seventy-five genetic loci influencing the human red blood cell

(2012) Pim van der Harst et al.   NATURE

An integrated encyclopedia of DNA elements in the human genome

(2012)   NATURE

An integrated map of genetic variation from 1,092 human genomes

(2012)   NATURE

BLUEPRINT to decode the epigenetic signature written in blood

(2012) David Adams et al.   NATURE BIOTECHNOLOGY

Roles for MSI2 and PROX1 in hematopoietic stem cell activity

(2011) Kristin J Hope et al.   CURRENT OPINION IN HEMATOLOGY

HaploReg: a resource for exploring chromatin states, conservation, and regulatory motif alterations within sets of genetically linked variants

(2011) L. D. Ward et al.   NUCLEIC ACIDS RESEARCH

A User's Guide to the Encyclopedia of DNA Elements (ENCODE)

(2011)   PLOS BIOLOGY

Sample Design and Cohort Selection in the Hispanic Community Health Study/Study of Latinos

(2010) Lisa M. LaVange et al.   ANNALS OF EPIDEMIOLOGY

Design and Implementation of the Hispanic Community Health Study/Study of Latinos

(2010) Paul D. Sorlie et al.   ANNALS OF EPIDEMIOLOGY

Identification of a PRMT5-dependent repressor complex linked to silencing of human fetal globin gene expression

(2010) G. Rank et al.   BLOOD

NKCC1 and hypertension: a novel therapeutic target involved in the regulation of vascular tone and renal function

(2010) Sergei N Orlov et al.   CURRENT OPINION IN NEPHROLOGY AND HYPERTENSION

MaCH: using sequence and genotype data to estimate haplotypes and unobserved genotypes

(2010) Yun Li et al.   GENETIC EPIDEMIOLOGY

Protein Quality Control During Erythropoiesis and Hemoglobin Synthesis

(2010) Eugene Khandros et al.   HEMATOLOGY-ONCOLOGY CLINICS OF NORTH AMERICA

Genome-wide association study of hematological and biochemical traits in a Japanese population

(2010) Yoichiro Kamatani et al.   NATURE GENETICS

New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk

(2010) Josée Dupuis et al.   NATURE GENETICS

A Genome-Wide Association Study of Red Blood Cell Traits Using the Electronic Medical Record

(2010) Iftikhar J. Kullo et al.   PLoS One

Decreased NKCC1 Activity in Erythrocytes From African Americans With Hypertension and Dyslipidemia

(2009) S. N. Orlov et al.   AMERICAN JOURNAL OF HYPERTENSION

Genome-wide association study identifies variants in TMPRSS6 associated with hemoglobin levels

(2009) John C Chambers et al.   NATURE GENETICS

Multiple loci influence erythrocyte phenotypes in the CHARGE Consortium

(2009) Santhi K Ganesh et al.   NATURE GENETICS

A genome-wide meta-analysis identifies 22 loci associated with eight hematological parameters in the HaemGen consortium

(2009) Nicole Soranzo et al.   NATURE GENETICS

PRMT5-mediated methylation of histone H4R3 recruits DNMT3A, coupling histone and DNA methylation in gene silencing

(2009) Quan Zhao et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Correlates of Anemia in American Blacks and Whites: The REGARDS Renal Ancillary Study

(2008) N. A. Zakai et al.   AMERICAN JOURNAL OF EPIDEMIOLOGY

Variability and heritability of hemoglobin concentration: an opportunity to improve understanding of anemia in older adults

(2008) K. V. Patel   HAEMATOLOGICA