A bacterial toxin-antitoxin module is the origin of inter-bacterial and inter-kingdom effectors of Bartonella

The BID Domain of Type IV Secretion Substrates Forms a Conserved Four-Helix Bundle Topped with a Hook

(2017) Frédéric V. Stanger et al.   STRUCTURE

The effector AvrRxo1 phosphorylates NAD in planta

(2017) Teja Shidore et al.   PLoS Pathogens

Gene Transfer Agent Promotes Evolvability within the Fittest Subpopulation of a Bacterial Pathogen

(2017) Maxime Québatte et al.   Cell Systems

Toxin-antitoxin systems in bacterial growth arrest and persistence

(2016) Rebecca Page et al.   Nature Chemical Biology

Genomic analysis of 38 Legionella species identifies large and diverse effector repertoires

(2016) David Burstein et al.   NATURE GENETICS

AvrRxo1 Is a Bifunctional Type III Secreted Effector and Toxin-Antitoxin System Component with Homologs in Diverse Environmental Contexts

(2016) Lindsay R. Triplett et al.   PLoS One

New insights into the role of Bartonella effector proteins in pathogenesis

(2015) Sabrina Siamer et al.   CURRENT OPINION IN MICROBIOLOGY

Contact-Dependent Growth Inhibition (CDI) and CdiB/CdiA Two-Partner Secretion Proteins

(2015) Julia L.E. Willett et al.   JOURNAL OF MOLECULAR BIOLOGY

The Phyre2 web portal for protein modeling, prediction and analysis

(2015) Lawrence A Kelley et al.   Nature Protocols

Secretion systems in Gram-negative bacteria: structural and mechanistic insights

(2015) Tiago R. D. Costa et al.   NATURE REVIEWS MICROBIOLOGY

Bacterial killing via a type IV secretion system

(2015) Diorge P. Souza et al.   Nature Communications

Adenylylation of Gyrase and Topo IV by FicT Toxins Disrupts Bacterial DNA Topology

(2015) Alexander Harms et al.   Cell Reports

A Plant Phosphoswitch Platform Repeatedly Targeted by Type III Effector Proteins Regulates the Output of Both Tiers of Plant Immune Receptors

(2014) Eui-Hwan Chung et al.   Cell Host & Microbe

An experimental strategy for the identification of AMPylation targets from complex protein samples

(2014) Kathrin Pieles et al.   PROTEOMICS

VgrG, Tae, Tle, and beyond: the versatile arsenal of Type VI secretion effectors

(2014) Eric Durand et al.   TRENDS IN MICROBIOLOGY

Social behavior and decision making in bacterial conjugation

(2014) Günther Koraimann et al.   Frontiers in Cellular and Infection Microbiology

The role of bacteriocins as selfish genetic elements

(2013) R. F. Inglis et al.   Biology Letters

Dual input control: activation of theBartonella henselae VirB/D4 type IV secretion system by the stringent sigma factor RpoH1 and the BatR/BatS two-component system

(2013) Maxime Québatte et al.   MOLECULAR MICROBIOLOGY

The Fic protein Doc uses an inverted substrate to phosphorylate and inactivate EF-Tu

(2013) Daniel Castro-Roa et al.   Nature Chemical Biology

A Gene Transfer Agent and a Dynamic Repertoire of Secretion Systems Hold the Keys to the Explosive Radiation of the Emerging Pathogen Bartonella

(2013) Lionel Guy et al.   PLoS Genetics

Agrobacterium infection and plant defense—transformation success hangs by a thread

(2013) Andrea Pitzschke   Frontiers in Plant Science

Adenylylation control by intra- or intermolecular active-site obstruction in Fic proteins

(2012) Philipp Engel et al.   NATURE

The Non-Flagellar Type III Secretion System Evolved from the Bacterial Flagellum and Diversified into Host-Cell Adapted Systems

(2012) Sophie S. Abby et al.   PLoS Genetics

ProtTest 3: fast selection of best-fit models of protein evolution

(2011) Diego Darriba et al.   BIOINFORMATICS

Transfer of R388 Derivatives by a Pathogenesis-Associated Type IV Secretion System into both Bacteria and Human Cells

(2011) Esther Fernández-González et al.   JOURNAL OF BACTERIOLOGY

The YopJ superfamily in plant-associated bacteria

(2011) JENNIFER D. LEWIS et al.   MOLECULAR PLANT PATHOLOGY

Diversity of bacterial type II toxin–antitoxin systems: a comprehensive search and functional analysis of novel families

(2011) Raphaël Leplae et al.   NUCLEIC ACIDS RESEARCH

Fic domain-catalyzed adenylylation: Insight provided by the structural analysis of the type IV secretion system effector BepA

(2011) Dinesh V. Palanivelu et al.   PROTEIN SCIENCE

A Novel Mechanism of Programmed Cell Death in Bacteria by Toxin–Antitoxin Systems Corrupts Peptidoglycan Synthesis

(2011) Hannes Mutschler et al.   PLOS BIOLOGY

Parallel Evolution of a Type IV Secretion System in Radiating Lineages of the Host-Restricted Bacterial Pathogen Bartonella

(2011) Philipp Engel et al.   PLoS Genetics

Toxin–antitoxin systems: why so many, what for?

(2010) Laurence Van Melderen   CURRENT OPINION IN MICROBIOLOGY

Interbacterial Macromolecular Transfer by the Campylobacter fetus subsp. venerealis Type IV Secretion System

(2010) S. Kienesberger et al.   JOURNAL OF BACTERIOLOGY

Silent Mischief: Bacteriophage Mu Insertions Contaminate Products of Escherichia coli Random Mutagenesis Performed Using Suicidal Transposon Delivery Plasmids Mobilized by Broad-Host-Range RP4 Conjugative Machinery

(2010) L. Ferrieres et al.   JOURNAL OF BACTERIOLOGY

Molecular recognition determinants for type IV secretion of diverse families of conjugative relaxases

(2010) Silvia Lang et al.   MOLECULAR MICROBIOLOGY

Within-host competition selects for plasmid-encoded toxin-antitoxin systems

(2010) T. F. Cooper et al.   PROCEEDINGS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

The Legionella Effector Protein DrrA AMPylates the Membrane Traffic Regulator Rab1b

(2010) M. P. Muller et al.   SCIENCE

The Trw Type IV Secretion System of Bartonella Mediates Host-Specific Adhesion to Erythrocytes

(2010) Muriel Vayssier-Taussat et al.   PLoS Pathogens

An efficient one-step site-directed deletion, insertion, single and multiple-site plasmid mutagenesis protocol

(2009) Huanting Liu et al.   BMC BIOTECHNOLOGY

Replication and conjugative mobilization of broad host-range IncQ plasmids

(2009) Richard Meyer   PLASMID

Fido, a Novel AMPylation Domain Common to Fic, Doc, and AvrB

(2009) Lisa N. Kinch et al.   PLoS One

Type VI secretion apparatus and phage tail-associated protein complexes share a common evolutionary origin

(2009) P. G. Leiman et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA