Atomistic fingerprint of hyaluronan–CD44 binding

Binding of Hyaluronan to the Native Lymphatic Vessel Endothelial Receptor LYVE-1 Is Critically Dependent on Receptor Clustering and Hyaluronan Organization

(2016) William Lawrance et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The glycocalyx promotes cooperative binding and clustering of adhesion receptors

(2016) Guang-Kui Xu et al.   Soft Matter

Design and syntheses of hyaluronan oligosaccharide conjugates as inhibitors of CD44-Hyaluronan binding

(2015) Xiaowei Lu et al.   GLYCOCONJUGATE JOURNAL

Molecular mechanism for the action of the anti-CD44 monoclonal antibody MEM-85

(2015) Jana Škerlová et al.   JOURNAL OF STRUCTURAL BIOLOGY

Revealing the Mechanisms of Protein Disorder and N-Glycosylation in CD44-Hyaluronan Binding Using Molecular Simulation

(2015) Olgun Guvench   Frontiers in Immunology

Tunable CD44-Specific Cellular Retargeting with Hyaluronic Acid Nanoshells

(2014) Morten F Ebbesen et al.   PHARMACEUTICAL RESEARCH

Terminal sialic acids on CD44 N-glycans can block hyaluronan binding by forming competing intramolecular contacts with arginine sidechains

(2014) Christina E. Faller et al.   PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS

GROMACS 4.5: a high-throughput and highly parallel open source molecular simulation toolkit

(2013) Sander Pronk et al.   BIOINFORMATICS

CD44 Receptor Unfolding Enhances Binding by Freeing Basic Amino Acids to Contact Carbohydrate Ligand

(2013) Amanda J. Favreau et al.   BIOPHYSICAL JOURNAL

The ‘order-to-disorder’ conformational transition in CD44 protein: An umbrella sampling analysis

(2013) Wojciech Plazinski et al.   JOURNAL OF MOLECULAR GRAPHICS & MODELLING

Comprehensive characterization of the N-glycosylation status of CD44s by use of multiple mass spectrometry-based techniques

(2012) Huanhuan Han et al.   ANALYTICAL AND BIOANALYTICAL CHEMISTRY

The High and Low Molecular Weight Forms of Hyaluronan Have Distinct Effects on CD44 Clustering

(2012) Cuixia Yang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Restricted dynamics of water around a protein–carbohydrate complex: Computer simulation studies

(2012) Madhurima Jana et al.   JOURNAL OF CHEMICAL PHYSICS

Conformational flexibility of a protein–carbohydrate complex and the structure and ordering of surrounding water

(2012) Madhurima Jana et al.   PHYSICAL CHEMISTRY CHEMICAL PHYSICS

Mechanism of Binding Site Conformational Switching in the CD44–Hyaluronan Protein–Carbohydrate Binding Interaction

(2011) Francis W. Jamison et al.   JOURNAL OF MOLECULAR BIOLOGY

Interactions between CD44 protein and hyaluronan: insights from the computational study

(2011) Wojciech Plazinski et al.   Molecular BioSystems

Complete reconstruction of an enzyme-inhibitor binding process by molecular dynamics simulations

(2011) I. Buch et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Analysis of CD44-Hyaluronan Interactions in an Artificial Membrane System

(2010) Patricia M. Wolny et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Two-State Conformations in the Hyaluronan-Binding Domain Regulate CD44 Adhesiveness under Flow Condition

(2010) Shinji Ogino et al.   STRUCTURE

Differential Activation of ERK and Rac Mediates the Proliferative and Anti-proliferative Effects of Hyaluronan and CD44

(2008) Devashish Kothapalli et al.   JOURNAL OF BIOLOGICAL CHEMISTRY