The glycocalyx promotes cooperative binding and clustering of adhesion receptors

Binding kinetics of membrane-anchored receptors and ligands: Molecular dynamics simulations and theory

(2015) Jinglei Hu et al.   JOURNAL OF CHEMICAL PHYSICS

Binding constants of membrane-anchored receptors and ligands: A general theory corroborated by Monte Carlo simulations

(2015) Guang-Kui Xu et al.   JOURNAL OF CHEMICAL PHYSICS

Integrin activation and internalization mediated by extracellular matrix elasticity: A biomechanical model

(2014) Guang-Kui Xu et al.   JOURNAL OF BIOMECHANICS

Superselective Targeting Using Multivalent Polymers

(2014) Galina V. Dubacheva et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

The cancer glycocalyx mechanically primes integrin-mediated growth and survival

(2014) Matthew J. Paszek et al.   NATURE

Sugar-coated cell signalling

(2014) Andrew J. Ewald et al.   NATURE

Predicted Rupture Force of a Single Molecular Bond Becomes Rate Independent at Ultralow Loading Rates

(2014) Dechang Li et al.   PHYSICAL REVIEW LETTERS

Physics of cell adhesion: some lessons from cell-mimetic systems

(2014) Erich Sackmann et al.   Soft Matter

Theory and Simulations of Adhesion Receptor Dimerization on Membrane Surfaces

(2013) Yinghao Wu et al.   BIOPHYSICAL JOURNAL

Muscle as a Metamaterial Operating Near a Critical Point

(2013) M. Caruel et al.   PHYSICAL REVIEW LETTERS

Binding constants of membrane-anchored receptors and ligands depend strongly on the nanoscale roughness of membranes

(2013) J. Hu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Tyrosine Replacement of PSGL-1 Reduces Association Kinetics with P- and L-Selectin on the Cell Membrane

(2012) Botao Xiao et al.   BIOPHYSICAL JOURNAL

Kinetics and Mechanics of Two-Dimensional Interactions between T Cell Receptors and Different Activating Ligands

(2012) Philippe Robert et al.   BIOPHYSICAL JOURNAL

Insights fromin situanalysis of TCR-pMHC recognition: response of an interaction network

(2012) Cheng Zhu et al.   IMMUNOLOGICAL REVIEWS

T Cell Receptor Signaling Is Limited by Docking Geometry to Peptide-Major Histocompatibility Complex

(2011) Jarrett J. Adams et al.   IMMUNITY

Probing mechanical principles of focal contacts in cell-matrix adhesion with a coupled stochastic-elastic modelling framework

(2011) H. Gao et al.   Journal of the Royal Society Interface

Transforming binding affinities from three dimensions to two with application to cadherin clustering

(2011) Yinghao Wu et al.   NATURE

Designing super selectivity in multivalent nano-particle binding

(2011) F. J. Martinez-Veracoechea et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The kinetics of two-dimensional TCR and pMHC interactions determine T-cell responsiveness

(2010) Jun Huang et al.   NATURE

TCR–peptide–MHC interactions in situ show accelerated kinetics and increased affinity

(2010) Johannes B. Huppa et al.   NATURE

Segregation of receptor–ligand complexes in cell adhesion zones: phase diagrams and the role of thermal membrane roughness

(2010) B Różycki et al.   NEW JOURNAL OF PHYSICS

Soft Matrices Suppress Cooperative Behaviors among Receptor-Ligand Bonds in Cell Adhesion

(2010) Jin Qian et al.   PLoS One

Lifetime and Strength of Periodic Bond Clusters between Elastic Media under Inclined Loading

(2009) Jin Qian et al.   BIOPHYSICAL JOURNAL

Progress in Mimetic Studies of Cell Adhesion and the Mechanosensing

(2009) Ana-Sunčana Smith et al.   CHEMPHYSCHEM

Theoretical study of the competition between cell-cell and cell-matrix adhesions

(2009) Guang-Kui Xu et al.   PHYSICAL REVIEW E

Binding cooperativity of membrane adhesion receptors

(2009) Heinrich Krobath et al.   Soft Matter

Integrin Clustering Is Driven by Mechanical Resistance from the Glycocalyx and the Substrate

(2009) Matthew J. Paszek et al.   PLoS Computational Biology

Nanoscale Increases in CD2-CD48-mediated Intermembrane Spacing Decrease Adhesion and Reorganize the Immunological Synapse

(2008) Oren Milstein et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Dynamics of Specific Vesicle-Substrate Adhesion: From Local Events to Global Dynamics

(2008) Ellen Reister-Gottfried et al.   PHYSICAL REVIEW LETTERS