Machine learning to design integral membrane channelrhodopsins for efficient eukaryotic expression and plasma membrane localization

A generic selection system for improved expression and thermostability of G protein-coupled receptors by directed evolution

(2016) Christoph Klenk et al.   Scientific Reports

Periscope: quantitative prediction of soluble protein expression in the periplasm of Escherichia coli

(2016) Catherine Ching Han Chang et al.   Scientific Reports

Crysalis: an integrated server for computational analysis and design of protein crystallization

(2016) Huilin Wang et al.   Scientific Reports

Biophysics of Channelrhodopsin

(2015) Franziska Schneider et al.   Annual Review of Biophysics

Genetically Encoded Spy Peptide Fusion System to Detect Plasma Membrane-Localized Proteins In Vivo

(2015) Claire N. Bedbrook et al.   CHEMISTRY & BIOLOGY

Mechanisms of Integral Membrane Protein Insertion and Folding

(2015) Florian Cymer et al.   JOURNAL OF MOLECULAR BIOLOGY

Energetics of Membrane Protein Folding

(2014) Karen G. Fleming   Annual Review of Biophysics

A review of machine learning methods to predict the solubility of overexpressed recombinant proteins in Escherichia coli

(2014) Narjeskhatoon Habibi et al.   BMC BIOINFORMATICS

Independent optical excitation of distinct neural populations

(2014) Nathan C Klapoetke et al.   NATURE METHODS

All-optical electrophysiology in mammalian neurons using engineered microbial rhodopsins

(2014) Daniel R Hochbaum et al.   NATURE METHODS

A large-scale evaluation of computational protein function prediction

(2013) Predrag Radivojac et al.   NATURE METHODS

Navigating the protein fitness landscape with Gaussian processes

(2013) P. A. Romero et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Overexpression of membrane proteins in mammalian cells for structural studies

(2012) Juni Andréll et al.   MOLECULAR MEMBRANE BIOLOGY

Crystal structure of the channelrhodopsin light-gated cation channel

(2012) Hideaki E. Kato et al.   NATURE

Chimeragenesis of distantly-related proteins by noncontiguous recombination

(2012) Matthew A. Smith et al.   PROTEIN SCIENCE

SCHEMA-Designed Variants of Human Arginase I and II Reveal Sequence Elements Important to Stability and Catalysis

(2012) Philip A. Romero et al.   ACS Synthetic Biology

The NumPy Array: A Structure for Efficient Numerical Computation

(2011) Stéfan van der Walt et al.   COMPUTING IN SCIENCE & ENGINEERING

Optogenetics in Neural Systems

(2011) Ofer Yizhar et al.   NEURON

Exploring protein fitness landscapes by directed evolution

(2009) Philip A. Romero et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY